Extracranial vertebral artery dissecting aneurysm presenting as vertebrobasilar stroke in a young adult: Case report of flow-diverter stenting
| datacite.rights | http://purl.org/coar/access_right/c_abf2 | |
| dc.contributor.author | Coronel, Maria Angelica | |
| dc.contributor.author | Luque-Llano, Melissa | |
| dc.contributor.author | Núñez-Bravo, Narledis | |
| dc.contributor.author | Rebolledo, Carlos | |
| dc.contributor.author | Barceló-Martínez, Ernesto | |
| dc.date.accessioned | 2025-12-04T21:41:30Z | |
| dc.date.available | 2025-12-04T21:41:30Z | |
| dc.date.issued | 2025 | |
| dc.description.abstract | Background: Extracranial vertebral artery aneurysms (EVAAs) are exceptionally rare vascular lesions and an uncommon cause of posterior circulation stroke. Their diagnosis is often delayed due to nonspecific symptoms, yet prompt recognition is essential to guide management. Objective: This study aimed to report a rare case of an extracranial vertebral artery dissecting aneurysm presenting as a posterior circulation stroke in a young adult, successfully managed with flow-diverter stenting. Clinical Case: A 33-year-old woman presented with sudden-onset dysarthria, vertigo, nausea, and vomiting. Brain magnetic resonance imaging revealed infarcts in the left occipital lobe, cerebellar peduncle, and both cerebellar hemispheres. Computed tomography angiography (CTA) demonstrated a fusiform aneurysm in the V2 segment of the left vertebral artery, and digital subtraction angiography (DSA) confirmed a dissecting aneurysm. The patient was successfully treated with a flow-diverting stent and remained stable at 6 months’ follow-up with mRS 1. Results: EVAA are uncommon but can manifest as posterior circulation ischemic events in young patients. Endovascular treatment with flow-diverting stents has been reported as a feasible option in selected cases, although evidence remains limited to case reports and small series. Conclusions: This case underscores the importance of considering rare yet potentially treatable etiologies of vertebrobasilar stroke in young patients and highlights the value of a multidisciplinary approach to management. | eng |
| dc.format.mimetype | ||
| dc.identifier.citation | Angelica-Coronel, M.; Luque-Llano, M.; Nuñez-Bravo, N.; Rebolledo, C.; Barceló-Martínez, E. Extracranial Vertebral Artery Dissecting Aneurysm Presenting as Vertebrobasilar Stroke in a Young Adult: Case Report of Flow-Diverter Stenting. Neurol. Int. 2025, 17, 187. https://doi.org/10.3390/neurolint17110187 | eng |
| dc.identifier.doi | https://www.mdpi.com/2035-8377/17/11/187# | |
| dc.identifier.issn | 20358377 (Electrónico) | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12442/17168 | |
| dc.identifier.url | https://www.mdpi.com/2035-8377/17/11/187 | |
| dc.language.iso | eng | |
| dc.publisher | MDPI | eng |
| dc.publisher | Ediciones Universidad Simón Bolívar | spa |
| dc.publisher | Facultad de Ciencias de la Salud | spa |
| dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | eng |
| dc.rights.accessrights | info:eu-repo/semantics/openAccess | |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.source | Neurology International | eng |
| dc.source | Neurol. Int. | eng |
| dc.source | Vol. 17 No. 11 Año 2025 | spa |
| dc.subject.keywords | Vertebral artery | eng |
| dc.subject.keywords | Aneurysm | eng |
| dc.subject.keywords | Stroke | eng |
| dc.subject.keywords | Young adult | eng |
| dc.subject.keywords | Stents | eng |
| dc.subject.keywords | Dissection | eng |
| dc.subject.keywords | Vertigo | eng |
| dc.subject.keywords | Endovascular procedures | eng |
| dc.subject.keywords | Case report | eng |
| dc.title | Extracranial vertebral artery dissecting aneurysm presenting as vertebrobasilar stroke in a young adult: Case report of flow-diverter stenting | eng |
| dc.type.driver | info:eu-repo/semantics/other | |
| dc.type.spa | Otros | |
| dcterms.references | Morasch, M.D.; Phade, S.V.; Naughton, P.; Garcia-Toca, M.; Escobar, G.; Berguer, R. Primary Extracranial Vertebral Artery Aneurysms. Ann. Vasc. Surg. 2013, 27, 418–423. | eng |
| dcterms.references | Strambo, D.; Peruzzotti-Jametti, L.; Semerano, A.; Fanelli, G.; Simionato, F.; Chiesa, R.; Rinaldi, E.; Martinelli, V.; Comi, G.; Bacigaluppi, M.; et al. Treatment Challenges of a Primary Vertebral Artery Aneurysm Causing Recurrent Ischemic Strokes. Case Rep. Neurol. Med. 2017, 2017, 2571630. | eng |
| dcterms.references | Rai, P.; Bhattacharya, K.; Rastogi, S.; Joshi, P.; Rabade, K.; Shetty, N.; Kulkarni, S. Beyond the Throat: Imaging of Parapharyngeal Space Lesions. Clin. Radiol. 2024, 79, 912–920. | eng |
| dcterms.references | Evans, K.; Lindert, R.-B.; Dyde, R.; Tse, G.H. Chronic Fusiform Extracranial Vertebral Artery Aneurysm with Recurrent Posterior Circulation Emboli: Case Report and Review of the Literature. Interv. Neuroradiol. 2022, 28, 9–15. | eng |
| dcterms.references | Stavrinou, L.C.; Stranjalis, G.; Stavrinou, P.C.; Bontozoglou, N.; Sakas, D.E. Extracranial Vertebral Artery Aneurysm Presenting as a Chronic Cervical Mass Lesion. Case Rep. Med. 2010, 2010, 938219. | eng |
| dcterms.references | Yang, L.; Ran, H. Extracranial Vertebral Artery Dissection: Findings and Advantages of Ultrasonography. Medicine 2018, 97, e0067. | eng |
| dcterms.references | Provenzale, J.M.; Sarikaya, B. Comparison of Test Performance Characteristics ofMRI,MR Angiography, and CT Angiography in the Diagnosis of Carotid and Vertebral Artery Dissection: A Review of theMedical Literature. Am. J. Roentgenol. 2009, 193, 1167–1174. | eng |
| dcterms.references | Teasdale, G.; Maas, A.; Lecky, F.; Manley, G.; Stocchetti, N.; Murray, G. The Glasgow Coma Scale at 40 Years: Standing the Test of Time. Lancet Neurol. 2014, 13, 844–854. | eng |
| dcterms.references | Alemseged, F.; Rocco, A.; Arba, F.; Schwabova, J.P.; Wu, T.; Cavicchia, L.; Ng, F.; Ng, J.L.; Zhao, H.; Williams, C.; et al. Posterior National Institutes of Health Stroke Scale Improves Prognostic Accuracy in Posterior Circulation Stroke. Stroke 2022, 53, 1247–1255. | eng |
| dcterms.references | Banks, J.L.; Marotta, C.A. Outcomes Validity and Reliability of the Modified Rankin Scale: Implications for Stroke Clinical Trials: A Literature Review and Synthesis. Stroke 2007, 38, 1091–1096. | eng |
| dcterms.references | Kulubya, E.S.; Yu, N.; Castillo, J.A.; Duong, H. External Carotid Artery-Radial Artery-Vertebral Artery Bypass for Surgical Treatment of Radiculopathy Caused by an Extracranial Vertebral Artery Aneurysm: A Case Report and Review of the Literature. Surg. Neurol. Int. 2023, 14, 29. | eng |
| dcterms.references | Pataki, Á.; Nguyen, D.T.; Nagy, Z.; Nardai, S.; Nemes, B. Stent-Graft Treatment of a Giant Asymptomatic Extracranial Vertebral Artery Aneurysm: Case Report and Literature Review. Ann. Vasc. Surg. 2022, 79, 442.e1–442.e6. | eng |
| dcterms.references | Wang, Y.; Jiao, L. Endovascular Treatment of a Primary Extracranial Vertebral Artery Aneurysm Causing Ischemic Stroke. Neurol. India 2021, 69, 184–186. | eng |
| dcterms.references | Schievink, W.I. Spontaneous Dissection of the Carotid and Vertebral Arteries. N. Engl. J. Med. 2001, 344, 898–906. | eng |
| dcterms.references | Nenadic, D.; Balevic, M.; Milojevic, M.; Tanskovic, S. Extracranial Vertebral Artery Aneurysm Rupture Complicated by Extrapleural Haematoma. EJVES Short Rep. 2018, 38, 12–14. | eng |
| dcterms.references | Rifkinson-Mann, S.; Laub, J.; Haimov, M. Atraumatic Extracranial Vertebral Artery Aneurysm: Case Report and Review of the Literature. J. Vasc. Surg. 1986, 4, 288–293. | eng |
| dcterms.references | Kim, H.S.; Choi, C.H.; Lee, T.H.; Kim, S.P. Fusiform Aneurysm Presenting with Cervical Radiculopathy in Ehlers-Danlos Syndrome. J. Korean Neurosurg. Soc. 2010, 48, 528. | eng |
| dcterms.references | Takahashi, S.; Katayama, K.; Tatsugawa, T.; Sueda, T. A Successful Hybrid Repair for Vertebral Arteriovenous Fistula with Extracranial Vertebral Artery Aneurysm. Ann. Vasc. Surg. 2015, 29, 126.e5–126.e8. | eng |
| dcterms.references | Cohen, J.E.; Gomori, J.M.; Rajz, G.; Rosenthal, G.; El Hassan, H.A.;Moscovici, S.; Itshayek, E. Vertebral Artery Pseudoaneurysms Secondary to Blunt Trauma: Endovascular Management by Means of Neurostents and Flow Diverters. J. Clin. Neurosci. 2016, 32, 77–82. | eng |
| dcterms.references | Plou, P.; Landriel, F.; Beltrame, S.; Hem, S.; Peralta, O.; García-Mónaco, R.; Yampolsky, C. Flow Diverter for the Treatment of Pseudoaneurysms of the Extracraneal Vertebral Artery: Report of Two Cases and Review of the Literature.World Neurosurg. 2019, 127, 72–78. | eng |
| dcterms.references | Qi, P.; Tong, X.; Liang, X.; Xue, X.;Wu, Z.; Feng, X.; Zhang, M.; Jiang, Z.;Wang, D.; Liu, A. Flow Diversion for Posterior Circulation Aneurysms: A Multicenter Retrospective Study. Ther. Adv. Neurol. Disord. 2023, 16, 17562864231176187 | eng |
| dcterms.references | Li, S.; Zeng, C.; Tao, W.; Huang, Z.; Yan, L.; Tian, X.; Chen, F. The Safety and Efficacy of Flow Diversion versus Conventional Endovascular Treatment for Intracranial Aneurysms: A Meta-Analysis of Real-World Cohort Studies from the Past 10 Years. Am. J. Neuroradiol. 2022, 43, 1004–1011. | eng |
| oaire.version | info:eu-repo/semantics/publishedVersion | |
| sb.programa | Especialización en Neurología | spa |
| sb.sede | Sede Barranquilla | spa |

