Relación de niveles de NS-1 con infección primaria/secundaria del virus del dengue en la costa colombiana.
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2022
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Ediciones Universidad Simón Bolívar
Facultad de Ciencias de la Salud
Facultad de Ciencias de la Salud
Resumen
Introducción: La infección por dengue es una enfermedad transmitida por la picadura del mosquito hembra Aedes, principalmente de la especie Aedes aegypti, cuyos síntomas inician de 4 a 7 días posterior a la picadura del mosquito caracterizados por fiebre , dolor de cabeza y erupción cutánea, asociada además a complicaciones graves como hemorragias y shock las cuales son desencadenadas por compromiso en la permeabilidad vascular y mecanismos que reducen volumen plaquetario , considerada una de las principales causas de morbilidad y mortalidad a nivel mundial.
Objetivo: Relacionar los niveles de NS-1 con infección primaria/secundaria del virus del dengue en el atlántico colombiano.
Metodología: se realizó un estudio analítico, longitudinal, retrospectivo de carácter cuantitativo, con la participación de 36 pacientes incluyendo hombres, mujeres y niños con sintomatología y diagnostico serológico confirmado por laboratorio para el virus del dengue, ubicados en el departamento del atlántico y magdalena entre el año 2018- 2020. Todos los datos de los pacientes se almacenaban en la base de datos REDCap de la Universidad George Washington.
Introduction: Dengue infection is a disease transmitted by the bite of the female Aedes mosquito, mainly of the Aedes aegypti species, whose symptoms begin 4 to 7 days after the mosquito bite, characterized by fever, headache and skin rash, also associated with to serious complications such as hemorrhage and shock which are triggered by compromised vascular permeability and mechanisms that reduce platelet volume, considered one of the main causes of morbidity and mortality worldwide. Objective: To relate the levels of NS-1 with primary/secondary dengue virus infection in the Colombian Atlantic. Methodology: An analytical, longitudinal, retrospective quantitative study was carried out, with the participation of 36 patients including men, women and children over 8 with symptoms and laboratory-confirmed serological diagnosis for dengue virus located in the department of the Atlantic and the cupcake between the years 2018-2020. All patient data was stored in the George Washington University REDCap database.
Introduction: Dengue infection is a disease transmitted by the bite of the female Aedes mosquito, mainly of the Aedes aegypti species, whose symptoms begin 4 to 7 days after the mosquito bite, characterized by fever, headache and skin rash, also associated with to serious complications such as hemorrhage and shock which are triggered by compromised vascular permeability and mechanisms that reduce platelet volume, considered one of the main causes of morbidity and mortality worldwide. Objective: To relate the levels of NS-1 with primary/secondary dengue virus infection in the Colombian Atlantic. Methodology: An analytical, longitudinal, retrospective quantitative study was carried out, with the participation of 36 patients including men, women and children over 8 with symptoms and laboratory-confirmed serological diagnosis for dengue virus located in the department of the Atlantic and the cupcake between the years 2018-2020. All patient data was stored in the George Washington University REDCap database.
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Palabras clave
Dengue, NS-1, Trombocitopenia, Fuga plasmática, Shock, Serotipos, Infección primaria, Infección secundaria, Thrombocytopenia, Plasma leak, Shock, Serotypes, Primary infection, Secondary infection
