Correlación de niveles de ácido úrico y complicaciones en preeclámpticas, Institución Prestadora de Salud, Barranquilla Julio - Noviembre 2025
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Fecha
2025
Autores
Rivera Obando, Leidy
Caicedo Portillo, Maira Ximena
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Ediciones Universidad Simón Bolívar
Facultad de Ciencias de la Salud
Facultad de Ciencias de la Salud
Resumen
Introducción: En mujeres con preeclampsia, los niveles séricos de ácido úrico suelen aumentar debido a una combinación de disminución de la filtración glomerular, aumento del catabolismo de purinas y estrés oxidativo endotelial, diversos estudios han encontrado que niveles elevados de ácido úrico se correlacionan con la severidad de la preeclampsia y con un mayor riesgo de complicaciones maternas, como eclampsia, síndrome HELLP, insuficiencia renal aguda y alteraciones hepáticas, encefalopatía posterior reversible y microangiopatía trombótica, así como complicaciones en el producto como mayor riesgo de ingreso a UCIN, bajo peso al nacer, distrés respiratorio, entre otras.
Introduction: In women with preeclampsia, serum uric acid levels often increase due to a combination of decreased glomerular filtration, increased purine catabolism, and endothelial oxidative stress. Several studies have found that elevated uric acid levels correlate with the severity of preeclampsia and with a higher risk of maternal complications, such as eclampsia, HELLP syndrome, acute renal failure and liver disorders, posterior reversible encephalopathy syndrome, and thrombotic microangiopathy, as well as complications in the infant, such as a higher risk of NICU admission, low birth weight, and respiratory distress, among others.
Introduction: In women with preeclampsia, serum uric acid levels often increase due to a combination of decreased glomerular filtration, increased purine catabolism, and endothelial oxidative stress. Several studies have found that elevated uric acid levels correlate with the severity of preeclampsia and with a higher risk of maternal complications, such as eclampsia, HELLP syndrome, acute renal failure and liver disorders, posterior reversible encephalopathy syndrome, and thrombotic microangiopathy, as well as complications in the infant, such as a higher risk of NICU admission, low birth weight, and respiratory distress, among others.
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Palabras clave
Eventos adversos, Preeclampsia, Ácido Úrico
