Changes in oxygenation and clinical outcomes with awake prone positioning in patients with suspected COVID-19 In Low-Resource settings: A retrospective cohort study
datacite.rights | http://purl.org/coar/access_right/c_abf2 | spa |
dc.contributor.author | Dueñas-Castell, Carmelo | |
dc.contributor.author | Borre-Naranjo, Diana | |
dc.contributor.author | Rodelo, Dairo | |
dc.contributor.author | Lora, Leydis | |
dc.contributor.author | Almanza, Amilkar | |
dc.contributor.author | Coronell, Wilfrido | |
dc.contributor.author | Rojas-Suarez, José | |
dc.date.accessioned | 2023-05-16T21:39:22Z | |
dc.date.available | 2023-05-16T21:39:22Z | |
dc.date.issued | 2023 | |
dc.description.abstract | Introduction: This study aimed to describe the use of awake prone positioning (APP) and conventional oxygen therapy (COT) in patients with suspected coronavirus disease (COVID-19) and respiratory failure in a limited-resource setting. Methods: This was a retrospective cohort study of hospitalized patients aged ≥18 years old who were placed in an awake prone position due to hypoxemic respiratory failure and suspected COVID-19. The patients were selected from a tertiary center in Cartagena, Colombia, between March 1, 2020, and August 31, 2020. Demographic, clinical, and laboratory variables were collated, and all the variables were compared between the groups. Results: The median age of the participants was 63 (IQR, 48.8-73) years (survivors: 59 [IQR, 43.568] years vs. non-survivors: 70 [IQR, 63-78] years, P ≤.001). Of the 1470 patients admitted for respiratory symptoms, 732 (49.8%) were hospitalized for more than 24 h, and 212 patients developed respiratory failure and required COT and APP (overall hospital mortality, 34% [73/212]). The mean rank difference in PaO2/FiO2 before and after APP was higher in the survivors than in the non-survivors (201.1-252.6, mean rank difference =51.5, P=.001 vs. 134.1-172.4, mean rank difference=38.28, P=.24, respectively). Conclusion: While using COT in conjunction with APP can improve respiratory failure in patients with suspected COVID-19 in low-resource settings, persistent hypoxemia after APP can identify patients with higher mortality risk. More evidence is needed to establish the role of this strategy. | spa |
dc.format.mimetype | spa | |
dc.identifier.doi | https://doi.org/10.1177/08850666211049333 | |
dc.identifier.issn | 15251489 | |
dc.identifier.issn | 08850666 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12442/12403 | |
dc.identifier.url | https://journals.sagepub.com/doi/full/10.1177/08850666211049333 | |
dc.language.iso | eng | eng |
dc.publisher | SAGE Publications | spa |
dc.publisher | Facultad de Ciencias de la Salud | spa |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | eng |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | spa |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.source | Journal of Intensive Care Medicine | eng |
dc.source | Vol 36 No. 11 (2023) | |
dc.subject | Awake prone position | eng |
dc.subject | Oxygenation | eng |
dc.subject | Respiratory failure | eng |
dc.subject | COVID-19 | eng |
dc.subject | Mortality | eng |
dc.subject | Resources | eng |
dc.title | Changes in oxygenation and clinical outcomes with awake prone positioning in patients with suspected COVID-19 In Low-Resource settings: A retrospective cohort study | eng |
dc.type.driver | info:eu-repo/semantics/article | spa |
dc.type.spa | Artículo científico | spa |
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oaire.version | info:eu-repo/semantics/publishedVersion | spa |
sb.programa | Especialización en Medicina Crítica y Cuidados Intensivos | spa |
sb.sede | Sede Barranquilla | spa |