Biomarcadores de respuesta inmune celular asociados con enfermedades crónicas no transmisibles
| datacite.rights | http://purl.org/coar/access_right/c_16ec | eng |
| dc.contributor.advisor | Peña Merlano, Engelbert | |
| dc.contributor.author | Acosta Redondo, Luz Dayana | |
| dc.contributor.author | Guzman Padilla, Alvaro Yesid | |
| dc.contributor.author | Padilla Ojeda, Kenneth David | |
| dc.date.accessioned | 2021-07-12T14:06:29Z | |
| dc.date.available | 2021-07-12T14:06:29Z | |
| dc.date.issued | 2020-06 | |
| dc.description.abstract | La respuesta adaptativa celular tiene como propósito fundamental la generación y liberación de Citocinas, moléculas de naturaleza proteica o glicoproteica que cumplen diversidad de funciones y son potencializadoras de todas las respuestas inmunes, siendo mayormente producidas por Linfocitos TCD4+ de todas las subpoblaciones, resultando más determinantes las generadas por los Th1 y Th2. Las citocinas actúan fundamentalmente como reguladores de las respuestas inmunitaria e inflamatoria. Esta respuesta resulta determinante en un sinnúmero de eventos y complicaciones, no siendo ajenas las enfermedades crónicas no trasmisibles. En el presente trabajo se pretende establecer el patrón de respuesta inmune adaptativa mediante el estudio de los niveles de interleucinas Th1 y Th2 en pacientes con enfermedades crónicas no transmisibles (ECNT) como Hipertensión Arterial (HTA), Diabetes Mellitus tipo 2 (DM2) y Cáncer para establecer la asociación de estas como Bio-marcadores de respuesta adaptativa celular y propender por la reducción de los índices de morbilidad y mortalidad en los individuos afectados. | spa |
| dc.description.abstract | The cellular adaptive response has as its fundamental purpose the generation and release of Cytokines, molecules of a protein or glycoprotein nature that fulfill a variety of functions and are potentiators of all immune responses, being mainly produced by TCD4 lymphocytes from all subpopulations, the generated by Th1 and Th2. Cytokines primarily act as regulators of immune and inflammatory responses. This response is decisive in countless events and complications, and non-communicable chronic diseases are not foreign. The present work aims to establish the adaptive immune response pattern by studying the levels of Th1 and Th2 interleukins in patients with chronic noncommunicable diseases such as Arterial Hypertension (AHT), Diabetes Mellitus type 2 (DM2) and Cancer in the city. from Barranquilla, Colombia during the period 2019 - 2020, to establish the association of these as Bio-markers of cellular adaptive response and promote the reduction of morbidity and mortality rates in affected individuals. | eng |
| dc.format.mimetype | spa | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12442/7972 | |
| dc.language.iso | spa | spa |
| dc.publisher | Ediciones Universidad Simón Bolívar | spa |
| dc.publisher | Facultad de Ciencias de la Salud | spa |
| dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | |
| dc.rights.accessrights | info:eu-repo/semantics/restrictedAccess | eng |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.subject | Linfocitos | spa |
| dc.subject | Citocinas | spa |
| dc.subject | Cáncer | spa |
| dc.subject | Biomarcadores | spa |
| dc.subject | Diabetes tipo 2 | spa |
| dc.title | Biomarcadores de respuesta inmune celular asociados con enfermedades crónicas no transmisibles | spa |
| dc.type.driver | info:eu-repo/semantics/bachelorThesis | eng |
| dc.type.spa | Trabajo de grado - pregrado | spa |
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| oaire.version | info:eu-repo/semantics/acceptedVersion | eng |
| sb.programa | Medicina | spa |
| sb.sede | Sede Barranquilla | spa |