Relación entre vulnerabilidad social y evolución del filtrado glomerular en pacientes con enfermedad renal poliquística

datacite.rightshttp://purl.org/coar/access_right/c_f1cf
dc.contributor.advisorAroca Martínez, Gustavo
dc.contributor.advisorGuido Musso, Carlos
dc.contributor.authorDulce Muñoz, Jaime Arturo
dc.date.accessioned2026-02-10T19:22:09Z
dc.date.available2026-02-10T19:22:09Z
dc.date.issued2025
dc.description.abstractLa enfermedad renal poliquística (ERP) es la nefropatía hereditaria más frecuente y una causa relevante de enfermedad renal crónica. Su evolución clínica es heterogénea y, aunque tradicionalmente se explica por factores genéticos y clínicos, existe creciente interés en el papel de los determinantes sociales de la salud. La vulnerabilidad social podría influir indirectamente en la progresión renal a través de barreras de acceso, adherencia y continuidad del cuidado, especialmente en contextos de alta desigualdad como el Caribe colombiano. Objetivo: Determinar la relación entre la vulnerabilidad social y la evolución del filtrado glomerular en pacientes con enfermedad renal poliquística atendidos en un centro de referencia del Caribe colombiano durante el periodo 2008–2025.spa
dc.description.abstractAutosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disorder and a major cause of chronic kidney disease. Its clinical course is highly heterogeneous and has traditionally been explained by genetic and clinical factors. However, increasing attention has been given to the role of social determinants of health. Social vulnerability may indirectly influence renal progression through barriers to access, treatment adherence, and continuity of care, particularly in regions with marked social inequality such as the Colombian Caribbean. Objective: To determine the relationship between social vulnerability and the evolution of glomerular filtration rate in patients with autosomal dominant polycystic kidney disease treated at a referral center in the Colombian Caribbean between 2008 and 2025.eng
dc.format.mimetypepdf
dc.identifier.urihttps://hdl.handle.net/20.500.12442/17347
dc.language.isospa
dc.publisherEdiciones Universidad Simón Bolívarspa
dc.publisherFacultad de Ciencias de la Salud.spa
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internationaleng
dc.rights.accessrightsinfo:eu-repo/semantics/embargoedAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectEnfermedad renal poliquísticaspa
dc.subjectVulnerabilidad socialspa
dc.subjectFiltrado glomerularspa
dc.subjectDeterminantes sociales de la saludspa
dc.subjectEnfermedad renal crónicaspa
dc.subject.keywordsAutosomal dominant polycystic kidney diseaseeng
dc.subject.keywordsSocial vulnerabilityeng
dc.subject.keywordsGlomerular filtration rateeng
dc.subject.keywordsSocial determinants of healtheng
dc.subject.keywordsChronic kidney diseaseeng
dc.titleRelación entre vulnerabilidad social y evolución del filtrado glomerular en pacientes con enfermedad renal poliquísticaspa
dc.type.driverinfo:eu-repo/semantics/other
dc.type.spaOtros
dcterms.referencesAuthors S. Autosomal Dominant Polycystic Kidney Disease [Internet]. Treasure Island (FL): StatPearls Publishing; 2025. Available from: https://www.ncbi.nlm.nih.gov/books/NBK532934/eng
dcterms.referencesPark J. Health disparities in kidney failure among patients with autosomal dominant polycystic kidney disease. Kidney Med. 2022;4(9):100502.eng
dcterms.referencesIrazabal M V, Rangel LJ, Bergstralh EJ. Imaging classification of autosomal dominant polycystic kidney disease: a simple model for selecting patients for clinical trials. J Am Soc Nephrol. 2015;26(1):160–72.eng
dcterms.referencesIrazabal M V, Rangel LJ, Bergstralh EJ. Imaging classification of autosomal dominant polycystic kidney disease: a simple model for selecting patients for clinical trials. J Am Soc Nephrol. 2015;26(1):160–72.eng
dcterms.referencesNorton JM. Social determinants of racial disparities in chronic kidney disease. J Am Soc Nephrol. 2016;27(9):2576–95.eng
dcterms.referencesAl-Chalabi S. Association of deprivation and its individual domains on outcomes in people with chronic kidney disease. Clin Kidney J. 2024;17(7):sfae086.eng
dcterms.referencesGabbai FB. Area deprivation and risk of death and chronic kidney disease progression in patients under nephrology care. Nephron. 2020;144(10):488– 98.eng
dcterms.referencesLi Y. Residential neighborhood disadvantage and access to kidney transplantation in the United States. JAMA Netw Open. 2025;8(1):e2450123.eng
dcterms.referencesNorris K, Beech B. Social Determinants of Kidney Health: Focus on Poverty. Clin J Am Soc Nephrol. 2021;16(5):809–11.eng
dcterms.referencesChebib FT, Torres VE. Recent advances in the management of autosomal dominant polycystic kidney disease. Clin J Am Soc Nephrol. 2018;13(11):1765–76.eng
dcterms.referencesColbert G, Elrggal M, Gaur L, Lerma E. Update and review of adult polycystic kidney disease. Disease-a-Month [Internet]. 2020;66(5):100887. Available from: https://doi.org/10.1016/j.disamonth.2019.100887eng
dcterms.referencesArs E, Bernis C, Fraga G, Furlano M, Martínez V, Martins J, et al. Documento de consenso de poliquistosis renal autosómica dominante del grupo de trabajo de enfermedades hereditarias de la Sociedad Española de Nefrología. Revisión 2020. Nefrología. 2022;42(4):367–89.spa
dcterms.referencesWilson P. Polycystic Kidney Disease. N Engl J Med. 2004;350(2):151–64.eng
dcterms.referencesPirson Y. Extrarenal Manifestations of Autosomal Dominant Polycystic Kidney Disease. Adv Chronic Kidney Dis [Internet]. 2010;17(2):173–80. Available from: http://dx.doi.org/10.1053/j.ackd.2010.01.003eng
dcterms.referencesCornec-Le Gall E, Alam A, Perrone RD. Autosomal dominant polycystic kidney disease. Lancet [Internet]. 2019;393(10174):919–35. Available from: http://dx.doi.org/10.1016/S0140-6736(18)32782-Xeng
dcterms.referencesXue C, Zhou C-C, Wu M, Mei C-L. The Clinical Manifestation and Management of Autosomal Dominant Polycystic Kidney Disease in China. Kidney Dis. 2016;2(3):111–9.eng
dcterms.referencesHelal I. Review Article Autosomal Dominant Polycystic Kidney Disease : New Insights into Treatment of Kidney Diseases and Transplantation. Saudi J Kidney Dis Transplant. 2013;24(2):230–4.eng
dcterms.referencesWilley CJ, Blais JD, Hall AK, Krasa HB, Makin AJ, Czerwiec FS. Prevalence of autosomal dominant polycystic kidney disease in the European Union. Nephrol Dial Transplant. 2017;32(8):1356–63.eng
dcterms.referencesGuatibonza YP, Rodríguez RE, Córdoba JP, Zarante I. Actualidad de la enfermedad renal poliquística. Univ Médica. 2012;54(1):53–68.eng
dcterms.referencesCamargo JT, González CA, Herrera L, Yomayusa-González N, Ibañez M, Valbuena-García AM, et al. Autosomal dominant polycystic kidney disease in Colombia. BMC Nephrol. 2023;24(1):1–6.eng
dcterms.referencesMusso CG, Ricardo AC, Aroca-Martinez G, Chaparro M. Chronic Kidney Disease (CKD) classification for low-resource settings: Taking into account patients’ social vulnerability. Rev Colomb Nefrol. 2024;11(3):1–8.eng
dcterms.referencesHarris PC, Torres VE. Polycystic Kidney Disease , Autosomal Dominant Summary [Internet]. Adam M, Everman D, editors. Gene Reviews. Seattle: National Center for Biotechnology Information; 2022. 1–44 p. Available from: https://www.dropbox.com/s/v69ld7wp3fubw1r/Bookshelf_NBK1246.pdf?dl=0eng
dcterms.referencesMontaña A, Patiño N, Larrate C, Zambrano FA, Martínez J, Lozano H, et al. Update on polycystic kidney disease. Rev Fac Med. 2018;66(1):107–16.eng
dcterms.referencesWilley C, Gauthier-Loiselle M, Cloutier M, Shi S, Maitland J, Stellhorn R, et al. Regional variations in prevalence and severity of autosomal dominant polycystic kidney disease in the United States. Curr Med Res Opin. 2021;37(7):1155–62.eng
dcterms.referencesUlasi I, Awobusuyi O, Nayak S, Ramachandran R, Musso C, Depine S. Chronic Kidney Disease Burden in Low-Resource Settings: Regional Perspectives. Semin Nephrol. 2022;42(151336).eng
dcterms.referencesMenezes LF, Germino GG. Systems biology of polycystic kidney disease. J Am Soc Nephrol. 2009;20(6):1193–203.eng
dcterms.referencesTorres VE, Harris PC. Mechanisms of disease: autosomal dominant and recessive polycystic kidney diseases. Nat Rev Nephrol. 2009;5(7):372–82.eng
dcterms.referencesHeyer CM. Predicted mutation strength of PKD1 correlates with severity of renal disease. J Am Soc Nephrol. 2016;27(9):2872–84.eng
dcterms.referencesGrantham JJ. Polycystic kidney disease: neoplasia in disguise. Am J Kidney Dis. 1990;15(2):110–6.eng
dcterms.referencesGrantham JJ. Volume progression in polycystic kidney disease. N Engl J Med. 2006;354(20):2122–30.eng
dcterms.referencesHigashihara E. Long-term progression of autosomal dominant polycystic kidney disease. Clin Exp Nephrol. 2012;16(4):622–8.eng
dcterms.referencesNowak KL. Overweight and obesity are predictors of progression in early ADPKD. J Am Soc Nephrol. 2018;29(2):571–8.eng
dcterms.referencesCrews DC. Socioeconomic factors and kidney disease. Semin Nephrol. 2013;33(4):371–9.eng
dcterms.referencesCavanaugh KL. Health literacy in patients with chronic kidney disease. Semin Dial. 2011;24(5):534–8.eng
dcterms.referencesNicholas SB. Socioeconomic disparities in chronic kidney disease. Adv Chronic Kidney Dis. 2015;22(1):6–15.eng
dcterms.referencesPatzer RE. Influence of race, ethnicity and socioeconomic status on kidney disease. Nat Rev Nephrol. 2012;8(9):533–41.eng
dcterms.referencesGarg PP. Income-based disparities in outcomes for patients with ESRD. J Am Soc Nephrol. 2001;12(12):2624–33.eng
dcterms.referencesChapman AB, Devuyst O, Eckardt KU. Autosomal-dominant polycystic kidney disease: executive summary from a KDIGO Controversies Conference. Kidney Int. 2015;88(1):17–27.eng
dcterms.referencesRossetti S, Kubly VJ, Consugar MB. Incompletely penetrant PKD1 alleles suggest a role for gene dosage in cyst initiation. J Am Soc Nephrol. 2009;20(2):409–16.eng
dcterms.referencesCornec-Le Gall E, Audrezet MP, Le Meur Y. Genotype–phenotype correlation in autosomal dominant polycystic kidney disease. J Am Soc Nephrol. 2013;24(6):1006–13.eng
dcterms.referencesVart P, Gansevoort RT, Joosten H. Socioeconomic disparities in chronic kidney disease: a systematic review. Nephrol Dial Transpl. 2015;30(4):657– 66.eng
dcterms.referencesBruce MA, Beech BM, Sims M. Social environmental stressors, psychological factors, and kidney disease. J Am Soc Nephrol. 2009;20(4):914–22.eng
dcterms.referencesGrubbs V, Plantinga LC, Tuot DS. Chronic kidney disease and neighborhood poverty in the United States. Clin J Am Soc Nephrol. 2014;9(12):2137–43.eng
dcterms.referencesHelal I, Reed B, McFann K. Racial differences in autosomal dominant polycystic kidney disease. J Am Soc Nephrol. 2012;23(2):314–23.eng
dcterms.referencesBelmonte Serrano MÁ. Requisitos éticos en los proyectos de investigación. Otra oveja negra. Semin la Fund Esp Reumatol. 2010;11(1):7–13.spa
dcterms.referencesEckardt K-U, others. Pathophysiology of renal anemia. Nephrol Dial Transplant. 2015;30(3):441–7.eng
dcterms.referencesVaziri ND. Disorders of lipid metabolism in chronic kidney disease. J Ren Nutr. 2014;24(1):73–6.eng
dcterms.referencesTonelli M, Wanner C. Dyslipidemia and chronic kidney disease. Kidney Int Suppl. 2011;1(3):19–25.eng
dcterms.referencesStauffer ME, Fan T. Prevalence of anemia in chronic kidney disease in the United States. PLoS One. 2014;9(1):e84943.eng
oaire.versioninfo:eu-repo/semantics/acceptedVersion
sb.programaEspecialización en Nefrologíaspa
sb.sedeSede Barranquillaspa

Archivos

Bloque original
Mostrando 1 - 2 de 2
No hay miniatura disponible
Nombre:
Resumen.pdf
Tamaño:
200 KB
Formato:
Adobe Portable Document Format
No hay miniatura disponible
Nombre:
PDF.pdf
Tamaño:
917 KB
Formato:
Adobe Portable Document Format
Bloque de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
2.93 KB
Formato:
Item-specific license agreed upon to submission
Descripción:

Colecciones