Relación entre vulnerabilidad social y evolución del filtrado glomerular en pacientes con enfermedad renal poliquística
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Fecha
2025
Autores
Dulce Muñoz, Jaime Arturo
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Ediciones Universidad Simón Bolívar
Facultad de Ciencias de la Salud.
Facultad de Ciencias de la Salud.
Resumen
La enfermedad renal poliquística (ERP) es la nefropatía hereditaria más frecuente y una causa relevante de enfermedad renal crónica. Su evolución clínica es heterogénea y, aunque tradicionalmente se explica por factores genéticos y clínicos, existe creciente interés en el papel de los determinantes sociales de la salud.
La vulnerabilidad social podría influir indirectamente en la progresión renal a través de barreras de acceso, adherencia y continuidad del cuidado, especialmente en contextos de alta desigualdad como el Caribe colombiano.
Objetivo: Determinar la relación entre la vulnerabilidad social y la evolución del filtrado glomerular en pacientes con enfermedad renal poliquística atendidos en un centro de referencia del Caribe colombiano durante el periodo 2008–2025.
Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disorder and a major cause of chronic kidney disease. Its clinical course is highly heterogeneous and has traditionally been explained by genetic and clinical factors. However, increasing attention has been given to the role of social determinants of health. Social vulnerability may indirectly influence renal progression through barriers to access, treatment adherence, and continuity of care, particularly in regions with marked social inequality such as the Colombian Caribbean. Objective: To determine the relationship between social vulnerability and the evolution of glomerular filtration rate in patients with autosomal dominant polycystic kidney disease treated at a referral center in the Colombian Caribbean between 2008 and 2025.
Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary kidney disorder and a major cause of chronic kidney disease. Its clinical course is highly heterogeneous and has traditionally been explained by genetic and clinical factors. However, increasing attention has been given to the role of social determinants of health. Social vulnerability may indirectly influence renal progression through barriers to access, treatment adherence, and continuity of care, particularly in regions with marked social inequality such as the Colombian Caribbean. Objective: To determine the relationship between social vulnerability and the evolution of glomerular filtration rate in patients with autosomal dominant polycystic kidney disease treated at a referral center in the Colombian Caribbean between 2008 and 2025.
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Palabras clave
Enfermedad renal poliquística, Vulnerabilidad social, Filtrado glomerular, Determinantes sociales de la salud, Enfermedad renal crónica
