Asociación entre noveles elevados de lipoproteína(a) (≥50 MG/DL) y la presencia de enfermedad cardiovascular aterosclerótica establecida en adultos de Barranquilla, Colombia
| datacite.rights | http://purl.org/coar/access_right/c_f1cf | |
| dc.contributor.advisor | Urina Triana, Manuel | |
| dc.contributor.advisor | Renowitzky Zabarain, Carlos | |
| dc.contributor.author | Mercado Marchena, Riguey Cecilia | |
| dc.date.accessioned | 2026-02-10T20:05:47Z | |
| dc.date.available | 2026-02-10T20:05:47Z | |
| dc.date.issued | 2026 | |
| dc.description.abstract | Antecedentes: La enfermedad cardiovascular aterosclerótica (ECVA) constituye una causa principal de morbimortalidad. La lipoproteína(a) es un marcador predominantemente genético con propiedades aterogénicas y protrombóticas; el umbral ≥50 mg/dL se usa con frecuencia para definir niveles elevados. En el Caribe colombiano, la evidencia clínica local sobre la frecuencia de Lp(a) elevada y su asociación con ECVA establecida es limitada. Objetivo: Analizar la asociación entre Lp(a) ≥50 mg/dL y la presencia de ECVA establecida en una población adulta atendida en Barranquilla, Colombia. Métodos: Estudio observacional analítico, transversal retrospectivo, realizado en una IPS de cuarto nivel en Barranquilla entre el 01 de enero de 2024 y el 30 de agosto de 2025. Se incluyeron adultos (≥18 años) con medición de Lp(a) y evaluación clínica documentada (n = 492), mediante muestreo no probabilístico por conveniencia. La exposición principal fue Lp(a). | spa |
| dc.description.abstract | Background: Atherosclerotic cardiovascular disease (ASCVD) is a leading cause of morbidity and mortality. Lipoprotein(a) [Lp(a)] is a predominantly genetically determined biomarker with atherogenic and prothrombotic properties; a threshold of ≥50 mg/dL is commonly used to define elevated levels. In the Colombian Caribbean region, local clinical evidence on the frequency of elevated Lp(a) and its association with established ASCVD is limited. Objective: To analyze the association between Lp(a) ≥50 mg/dL and the presence of established ASCVD in an adult population receiving care in Barranquilla, Colombia. Methods: An observational, analytical, retrospective cross-sectional study was conducted at a quaternary-care institution in Barranquilla between January 1, 2024 and August 30, 2025. Adults (≥18 years) with an Lp(a) measurement and documented clinical evaluation were included (n = 492) using non-probabilistic convenience sampling. The primary exposure was Lp(a) | eng |
| dc.format.mimetype | ||
| dc.identifier.uri | https://hdl.handle.net/20.500.12442/17348 | |
| dc.language.iso | spa | |
| dc.publisher | Ediciones Universidad Simón Bolívar | spa |
| dc.publisher | Facultad de Ciencias de la Salud | spa |
| dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | eng |
| dc.rights.accessrights | info:eu-repo/semantics/embargoedAccess | |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.subject | Lipoproteína(a) | spa |
| dc.subject | Enfermedad cardiovascular aterosclerótica | spa |
| dc.subject | Factores de riesgo | spa |
| dc.subject | Estudios transversales | spa |
| dc.subject.keywords | Lipoprotein(a) | eng |
| dc.subject.keywords | Atherosclerotic cardiovascular disease | eng |
| dc.subject.keywords | Risk factors | eng |
| dc.subject.keywords | Cross-sectional studies | eng |
| dc.title | Asociación entre noveles elevados de lipoproteína(a) (≥50 MG/DL) y la presencia de enfermedad cardiovascular aterosclerótica establecida en adultos de Barranquilla, Colombia | spa |
| dc.type.driver | info:eu-repo/semantics/other | |
| dc.type.spa | Otros | |
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| oaire.version | info:eu-repo/semantics/acceptedVersion | |
| sb.programa | Especialización en Cardiología | spa |
| sb.sede | Sede Barranquilla | spa |
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