Factores de riesgo asociados a sobreinfección bacteriana pulmonar y perfil microbiológico en pacientes con SARSCOV-2 intubados en una unidad de cuidados intensivos de la ciudad de Barranquilla
| datacite.rights | http://purl.org/coar/access_right/c_16ec | |
| dc.contributor.advisor | Algarín, Holmes | |
| dc.contributor.advisor | Núñez-Bravo, Narledis | |
| dc.contributor.author | Rudas Moscarella, Juan Manuel | |
| dc.date.accessioned | 2022-07-14T14:38:54Z | |
| dc.date.available | 2022-07-14T14:38:54Z | |
| dc.date.issued | 2022 | |
| dc.description.abstract | Antecedentes: La COVID-19, enfermedad respiratoria aguda causada por el Coronavirus SARS-CoV2 emergió en diciembre de 2019, cuando se reportaron sus primeros casos en Wuhan, China, y meses después fue declarada pandemia por la OMS el 11 de marzo de 2020. Desde el inicio se comprendió su severidad y fueron reconocidos los grupos capaces de enfrentar mayores complicaciones, sobre todo aquellos conformados por pacientes con comorbilidades como Hipertensión Arterial, Enfermedad Cardiovascular, Hábito de fumar, Enfermedad Respiratoria Crónica, Enfermedad Renal Crónica, Enfermedad Hepática Crónica e Inmunodeficiencias; todas estas aumentan el riesgo de complicaciones, dentro de las cuales las sobreinfecciones se asocian a mayor mortalidad. Objetivo: Determinar los factores de riesgo asociados a sobreinfección bacteriana pulmonar y describir el perfil microbiológico en pacientes con SARSCoV-2 intubados en una Unidad de Cuidados Intensivos de la ciudad de Barranquilla, periodo 2021. Materiales y Métodos: se realizó un estudio de casos y controles diseñado bajo fundamentos cuantitativos. La población estuvo compuesta por pacientes críticamente enfermos por infección por SARSCoV-2 ingresados a una Unidad de Cuidados Intensivos de un IPS de la ciudad de Barranquilla. | spa |
| dc.description.abstract | Background: COVID-19, an acute respiratory illness caused by the SARS-CoV2 Coronavirus, emerged in December 2019, when its first cases were reported in Wuhan, China, and months later it was declared a pandemic by the WHO on March 11, 2020. From the beginning, its severity was understood and the groups capable of facing greater complications were recognized, especially those made up of patients with comorbidities such as Arterial Hypertension, Cardiovascular Disease, Smoking Habit, Chronic Respiratory Disease, Chronic Kidney Disease, Chronic Liver Disease and Immunodeficiencies; all of these increase the risk of complications, within which superinfections are associated with higher mortality. Objective: To determine the risk factors associated with pulmonary bacterial superinfection and describe the microbiological profile in patients with SARSCoV-2 intubated in an Intensive Care Unit in the city of Barranquilla, period 2021. Materials and Methods: a case-control study designed under quantitative foundations was carried out. The population isaccompanied by critically ill patients with SARSCoV-2 infection admitted to an Intensive Care Unit of an IPS in the city of Barranquilla. | eng |
| dc.format.mimetype | ||
| dc.identifier.uri | https://hdl.handle.net/20.500.12442/10240 | |
| dc.language.iso | spa | |
| dc.publisher | Ediciones Universidad Simón Bolívar | spa |
| dc.publisher | Facultad de Ciencias de la Salud | spa |
| dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | eng |
| dc.rights.accessrights | info:eu-repo/semantics/restrictedAccess | spa |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.subject | Covid | spa |
| dc.subject | Sobreinfección | spa |
| dc.subject | Intubación | spa |
| dc.subject | Superinfection | eng |
| dc.subject | Intubation | eng |
| dc.title | Factores de riesgo asociados a sobreinfección bacteriana pulmonar y perfil microbiológico en pacientes con SARSCOV-2 intubados en una unidad de cuidados intensivos de la ciudad de Barranquilla | spa |
| dc.type.driver | info:eu-repo/semantics/other | |
| dc.type.spa | Otros | |
| dcterms.references | WHO Coronavirus (COVID-19) Dashboard. Disponible en: https://covid19.who.int/ | spa |
| dcterms.references | Peng YD, Meng K, Guan HQ, et al. Clinical characteristics and outcomes of 112 cardiovascular disease patients infected by 2019-nCoV. Mar 2. 2020. p. 48 | eng |
| dcterms.references | Rubin R. What Happens When COVID-19 Collides With Flu Season? JAMA. 2020;324(10):923-925. doi: 10.1001 / jama.2020.15260 | eng |
| dcterms.references | Organización Mundial de la Salud. Coronavirus disease (COVID-19) outbreak. Ginebra: OMS; 2020. Disponible en: https://www.who. int/emergencies/diseases/novel-coronavirus-2019 | spa |
| dcterms.references | Zhou F, Yu T, Du R, Fan G, Liu Y, Liu Z, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The Lancet. 2020;395(10229):1054-1062 | eng |
| dcterms.references | Organización Mundial de la Salud. Clinical care of severe acute respiratory infections – Tool kit. COVID-19 adaptation. Ginebra : OMS ; 2020. Disponible en: https://www.who.int/publications/i/item/ clinical-care-of-severe-acute-respiratory-infections-tool-ki | eng |
| dcterms.references | Organización Mundial de la Salud. Clinical management of severe acute respiratory infection when COVID-19 is suspected. Ginebra: OMS; 2020. Disponible en: https://www.who.int/ publications-detail/clinical-management-of-severe-acuterespiratory-infection-when-novel-coronavirus-(ncov)-infectionis-suspected. | eng |
| dcterms.references | Parohan M, Yaghoubi S, Seraji A, Javanbakht MH, Sarraf P, Djalali M. Risk factors for mortality in patients with Coronavirus disease 2019 (COVID-19) infection: a systematic review and meta-analysis of observational studies. The Aging Male. 2020;23(5):1416-1424 | eng |
| dcterms.references | Kim D, Quinn J, Pinsky B, Shah NH, Brown I. Rates of Co-infection Between SARS-CoV-2 and Other Respiratory Pathogens. JAMA. 2020;323(20):2085-6. 10. Aguilera-Calzadilla Y, Diaz-Morales Y, Ortiz-Díaz L, González--Martínez O, Lovelle-Enríquez O, Sánchez-Álvarez M. Infecciones bacterianas asociadas a la COVID-19 en pacientes de una unidad de cuidados intensivos. Revista Cubana de Medicina Militar. 2020; 49 (3) | eng |
| dcterms.references | Rawson TM, Moore LSP, Zhu N, Ranganathan N, Skolimowska K, Gilchrist M, et al. Bacterial and fungal co-infection in individuals with coronavirus: A rapid review to support COVID-19 antimicrobial prescribing. Clin Infect Dis. 2020; 0954162(478):1-4. | eng |
| dcterms.references | Singh V, Upadhyay P, Reddy J, Granger J. SARS-CoV-2 respiratory co-infections: Incidence of viral and bacterial co-pathogens. Int J Infect Dis 2021;105:617–20 | eng |
| dcterms.references | Zhu, X., Ge, Y., Wu, T., Zhao, K., Chen, Y., Wu, B., Zhu, F., Zhu, B., & Cui, L. (2020). Co-infection with respiratory pathogens among COVID-2019 cases. Virus research, 285, 198005. https://doi.org/10.1016/j.virusres.2020.198005. | eng |
| dcterms.references | Lansbury, L., Lim, B., Baskaran, V., & Lim, W. S. (2020). Co-infections in people with COVID-19: a systematic review and meta-analysis. The Journal of infection, 81(2), 266–275. https://doi.org/10.1016/j.jinf.2020.05.046. | eng |
| dcterms.references | Song W, Jia X, Zhang X, Ling Y, Yi Z. Co-infection in COVID-19, a cohort study. J Infect. 2021;82(3):414-51. https://doi.org/10.1016/j.jinf.2020.10.006 | eng |
| dcterms.references | De Francesco MA, Poiesi C, Gargiulo F, Bonfanti C, Pollara P, Fiorentini S, et al. Coinfection of chlamydia pneumoniae and mycoplasma pneumoniae with SARS-CoV-2 is associated with more severe features. J Infect. abril de 2021;82(4):e4-7. https://doi.org/10.1016/j.jinf.2021.01.009. | eng |
| dcterms.references | Feng Y, Ling Y, Bai T, Xie Y, Huang J, Li J, et al. COVID-19 with Different Severities: A Multicenter Study of Clinical Features. Am J Respir Crit Care Med. 2020;201(11):1380- 8. https://doi .org/10.1164/rccm.202002-0445OC. | eng |
| dcterms.references | Contou D, Claudinon A, Pajot O, Micaëlo M, Longuet Flandre P, Dubert M, et al. Bacterial and viral co-infections in patients with severe SARS-CoV-2 pneumonia admitted to a French ICU. Ann Intensive Care.2020;10:119. PMC7475952 | eng |
| dcterms.references | Garcia-Vidal C et al., Incidence of co-infections and superinfections in hospitalized patients with COVID-19: a retrospective cohort study, Clinical Microbiology and Infection, https://doi.org/10.1016/j.cmi.2020.07.041. | eng |
| dcterms.references | Consenso colombiano de atención, diagnóstico y manejo de la infección por SARS-COV-2/COVID-19 en establecimientos de atención de la salud. Recomendaciones basadas en consenso de expertos e informadas en la evidencia. Infectio. Revista de la Asociación Colombiana de Infectología. 2021;3:1-491 | spa |
| dcterms.references | Manna S, Baindara P, Mandal SM. Molecular pathogenesis of secondary bacterial infection associated to viral infections including SARS-CoV-2 . Journal of Infection and Public Health. Elsevier Ltd; 2020;13:1397–404. | eng |
| dcterms.references | Bosch AATM, Biesbroek G, Trzcinski K, Sanders EAM, Bogaert D. Viral and Bacterial Interactions in the Upper Respiratory Tract. PLoS Pathogens. Public Library of Science; 2013;9 | eng |
| dcterms.references | Hughes S, Troise O, Donaldson H, Mughal N, Moore LSP. Bacterial and fungal coinfection among hospitalized patients with COVID-19: a retrospective cohort study in a UK secondary-care setting. Clin Microbiol Infect. 2020;26(10):1395–9 | eng |
| dcterms.references | Nebreda-Mayoral T, Miguel-Gómez MA, March-Rosselló GA, Puente- Fuertes L, Cantón-Benito E, Martínez-García AM, et al. Bacterial/fungal infection in hospitalized patients with COVID-19 in a tertiary hospital in the Community of Castilla y León, Spain. Enferm Infecc Microbiol Clin. 2021. | eng |
| dcterms.references | Zhang H, Zhang Y, Wu J, Li Y, Zhou X, Li X, et al. Risks and features of secondary infections in severe and critical ill COVID-19 patients. Emerg Microbes Infect. 2020;9(1):1958–64. | eng |
| dcterms.references | Li J, Wang J, Yang Y, Cai P, Cao J, Cai X, et al. Etiology and antimicrobial resistance of secondary bacterial infections in patients hospitalized with COVID-19 in Wuhan, China: a retrospective analysis. Antimicrob Resist Infect Control. 2020;9(1). | eng |
| dcterms.references | Lv Z, Cheng S, Le J, Huang J, Feng L, Zhang B, et al. Clinical characteristics and co-infections of 354 hospitalized patients with COVID-19 in Wuhan, China: a retrospective cohort study. Microbes Infect.2020;22(4–5):195–9. | eng |
| dcterms.references | Sieswerda E, de Boer MGJ, Bonten MMJ, Boersma WG, Jonkers RE, Aleva RM, et al. Recommendations for antibacterial therapy in adults with COVID-19 – an evidence based guideline. Clinical Microbiology and Infection. Elsevier B.V.; 2021;27:61–6. | eng |
| dcterms.references | Rodriguez-Morales AJ, Cardona-Ospina JA, Gutiérrez-Ocampo E, Villamizar-Peña R, Holguin-Rivera Y, Escalera-Antezana JP, et al. Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis. Travel Medicine and Infectious Disease. Elsevier USA; 2020;24. | eng |
| dcterms.references | Metlay JP, Waterer GW, Long AC, Anzueto A, Brozek J, Crothers K, et al. Diagnosis and treatment of adults with community-acquired pneumonia. Am J Respir Crit Care Med. 2019;200(7):E45–67 | eng |
| dcterms.references | Collins ME, Popowitch EB, Miller MB. Evaluation of a novel multiplex PCR panel compared to quantitative bacterial culture for diagnosis of lower respiratory tract infections. J Clin Microbiol. 2020;58(5):2013–3 | eng |
| dcterms.references | European Centre for Disease Prevention and Control. Threat Assessment Brief: Reinfection with SARS-CoV-2: considerations for public health response. 2020. | eng |
| dcterms.references | Giacobbe DR, Battaglini D, Ball L, Brunetti I, Bruzzone B, Codda G, et al. Bloodstream infections in critically ill patients with COVID-19. Eur J Clin Invest. 2020;50(10). | eng |
| dcterms.references | Luyt CE, Sahnoun T, Gautier M, Vidal P, Burrel S, Pineton de Chambrun M, et al. Ventilator-associated pneumonia in patients with SARS-CoV- 2-associated acute respiratory distress syndrome requiring ECMO: a retrospective cohort study. Ann Intensive Care. 2020;10(1). | eng |
| dcterms.references | Razazi K, Arrestier R, Haudebourg AF, Benelli B, Carteaux G, Decousser J -W, et al. Risks of ventilator-associated pneumonia and invasive pulmonary aspergillosis in patients with viral acute respiratory distress syndrome related or not to Coronavirus 19 disease. Crit Care. 2020;24(1). | eng |
| dcterms.references | Bardi T, Pintado V, Gomez-Rojo M, Escudero-Sanchez R, Azzam Lopez A, Diez-Remesal Y, et al. Nosocomial infections associated to COVID-19 in the intensive care unit: clinical characteristics and outcome. Eur J Clin Microbiol Infect Dis. 2021;40(3):495– 502. | eng |
| dcterms.references | Wu CP, Adhi F, Highland K. Recognition and management of respiratory coinfection and secondary bacterial pneumonia in patients with COVID-19: Posted april 27, 2020. Cleve Clin J Med. 2020;87(5):1–5. | eng |
| dcterms.references | Cataño-Correa JC, Cardona-Arias JA, Porras Mancilla JP, García MT. Bacterial superinfection in adults with COVID-19 hospitalized in two clinics in Medellín-Colombia, 2020. PLoS ONE 2021;16(7): e0254671. https://doi.org/10.1371/journal.pone.0254671 | eng |
| dcterms.references | Li R, Pei S, Chen B, Song Y, Zhang T, Yang W, et al. Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV-2). Science 202; 368(6490):489–93. https://doi.org/10.1126/science.abb3221 PMID: 32179701 | eng |
| dcterms.references | Shen Z, Xiao Y, Kang L, Ma W, Shi L, Zhang L, et al. Genomic diversity of SARS-CoV-2 in Coronavirus Disease 2019 patients. Clin Infect Dis 2020; 71:713–20. https://doi.org/10.1093/cid/ciaa203 PMID:32129843 | eng |
| dcterms.references | Velazquez D, Villacob R, Algarin H. Gonzalez H. Coinfección Bacteriana en los Pacientes con SARSCoV-2 Intubados en la Unidad de Cuidados Intensivos en una IPS de Barranquilla (Atl, CO). Tesis Doctoral en medicina critica y cuidados intensivos. Universidad Simón Bolívar. 2021. Disponible en: https://bonga.unisimon.edu.co/handle/20.500.12442/7790 | spa |
| dcterms.references | 42. Velavan TP, Meyer CG. The COVID‐19 epidemic. Trop Med Int Heal 2020;25:278–80. doi:10.1111/tmi.13383 | eng |
| dcterms.references | Correia G, Rodrigues L, Gameiro da Silva M, et al. Airborne route and bad use of ventilation systems as non-negligible factors in SARS-CoV-2 transmission. Med Hypotheses 2020;141:109781. doi:10.1016/j.mehy.2020.109781 | eng |
| dcterms.references | Ahn D-G, Shin H-J, Kim M-H, et al. Current Status of Epidemiology, Diagnosis, Therapeutics, and Vaccines for Novel Coronavirus Disease 2019 (COVID-19). J Microbiol Biotechnol 2020;30:313–24. doi:10.4014/jmb.2003.03011 | eng |
| dcterms.references | Rothan HA, Byrareddy SN. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. J Autoimmun 2020;109:102433. doi:10.1016/j.jaut.2020.102433 | eng |
| dcterms.references | Lu L, Zhong W, Bian Z, et al. A comparison of mortality-related risk factors of COVID-19, SARS, and MERS: A systematic review and meta-analysis. J Infect 2020;81:e18–25. doi:10.1016/j.jinf.2020.07.002 | eng |
| dcterms.references | Lu L, Zhong W, Bian Z, et al. A comparison of mortality-related risk factors of COVID-19, SARS, and MERS: A systematic review and meta-analysis. J Infect 2020;81:e18–25. doi:10.1016/j.jinf.2020.07.002 | eng |
| dcterms.references | Prieto-Alhambra D, Balló E, Coma E, et al. Filling the gaps in the characterization of the clinical management of COVID-19: 30-day hospital admission and fatality rates in a cohort of 118 150 cases diagnosed in outpatient settings in Spain. Int J Epidemiol Published Online First: 29 October 2020. doi:10.1093/ije/dyaa190 | eng |
| dcterms.references | Douthit BJ. The influence of the learning health system to address the COVID19 pandemic: An examination of early literature. Int J Health Plann Manage Published Online First: 26 October 2020. doi:10.1002/hpm.3088 | eng |
| dcterms.references | Jiang B, Yao W, Wang T, et al. Tracheal intubation in COVID-19 patients: update on recommendations. Response to Br J Anaesth 2020; 125:e424–6. doi:10.1016/j.bja.2020.08.019 | eng |
| dcterms.references | Meng L, Qiu H, Wan L, et al. Intubation and Ventilation amid the COVID-19 Outbreak. Anesthesiology 2020;132:1317–32. doi:10.1097/ALN.0000000000003296 | eng |
| dcterms.references | Bravo Quiroga L, Sánchez Fraga S. Neumonías nosocomiales y asociadas a ventilación mecánica invasiva. Med - Programa Form Médica Contin Acreditado 2018;12:3763–9. doi:10.1016/j.med.2018.10.003 | spa |
| dcterms.references | Bravo Quiroga L, Sánchez Fraga S. Neumonías nosocomiales y asociadas a ventilación mecánica invasiva. Med - Programa Form Médica Contin Acreditado 2018;12:3763–9. doi:10.1016/j.med.2018.10.003 | spa |
| dcterms.references | Hassan SA, Sheikh FN, Jamal S, et al. Coronavirus (COVID-19): A Review of Clinical Features, Diagnosis, and Treatment. Cureus 2020;12. doi:10.7759/cureus.7355 | eng |
| dcterms.references | Guo Z-D, Wang Z-Y, Zhang S-F, et al. Aerosol and Surface Distribution of Severe Acute Respiratory Syndrome Coronavirus 2 in Hospital Wards, Wuhan, China, 2020. Emerg Infect Dis 2020;26:1583–91. doi:10.3201/eid2607.200885 | eng |
| dcterms.references | Li G, Fan Y, Lai Y, et al. Coronavirus infections and immune responses. J Med Virol 2020;92:424–32. doi:10.1002/jmv.25685 | spa |
| oaire.version | info:eu-repo/semantics/acceptedVersion | |
| sb.programa | Especialización en Medicina Crítica y Cuidados Intensivos | spa |
| sb.sede | Sede Barranquilla | spa |