Estudio de bacteriófagos como modelo de terapia antimicrobiana
| datacite.rights | http://purl.org/coar/access_right/c_16ec | eng |
| dc.contributor.advisor | Acosta Hoyos, Antonio | spa |
| dc.contributor.author | López Arévalo, Mary Isabel | spa |
| dc.contributor.author | Márquez Ariza, Carlos Mario | spa |
| dc.contributor.author | Marenco Salazar, Juan David | spa |
| dc.contributor.author | Rojas Garrido, Roxana Milena | spa |
| dc.date.accessioned | 2024-03-11T20:16:51Z | |
| dc.date.available | 2024-03-11T20:16:51Z | |
| dc.date.issued | 2014 | |
| dc.description.abstract | La resistencia bacteriana es uno de los mayores problemas en salud pública evidenciado por el aumento considerable en la tasa de tratamientos fallidos en enfermedades infecciosas; esto como consecuencia de la alta resistencia a los agentes antimicrobianos. Los bacteriófagos son virus que infectan a las bacterias y podrían postularse como una terapia alternativa para dichas enfermedades, ya que son seguros, específicos, no infectan a la especie humana y son capaces de adaptarse a los cambios que la bacteria genere y así matarlas. Metodología: Se obtuvieron muestras del rio Magdalena y se sometió a técnicas para aislamiento de fagos, de cepas resistentes de E, coli y klebsiella pneumoniae para el enriquecimiento inicial de bacteriófagos de rio; luego se aisló el fago y se contaron las unidades formadoras de placas. | spa |
| dc.description.abstract | Bacterial resistance is a major public health problem today as evidenced by the significant increase in the rate of failure in infectious disease treatments; this is due to the high resistance to antimicrobial agents. Bacteriophages are visures that infect bacteria and could stand as an alternative therapy for these infections, because they are safe, specific, do not infect the human species and are able to adapt to changes by their host bacteria. Water samples were obtained from the Magdalena River, and was subject to several molecular biology techniques for phage enrichment. Multiresistant E. coli and klebsiella pneumoniae was used in this study and was challenged with river water fracttions for phage isolation. | eng |
| dc.format.mimetype | spa | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12442/14319 | |
| dc.language.iso | spa | spa |
| dc.publisher | Ediciones Universidad Simón Bolívar | spa |
| dc.publisher | Facultad de Ciencias de la Salud | spa |
| dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | eng |
| dc.rights.accessrights | info:eu-repo/semantics/restrictedAccess | eng |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.subject | Bacteriófago | spa |
| dc.subject | Aislamiento | spa |
| dc.subject | Cultivo | spa |
| dc.subject | Terapia antimicrobiana | spa |
| dc.subject | Unidades formadoras de placas | spa |
| dc.subject | Klebsiella pneumonie | eng |
| dc.subject | Bacteriophage | eng |
| dc.subject | Isolation | eng |
| dc.subject | Culture | eng |
| dc.subject | Antimicrobial therapy | eng |
| dc.subject | Plaque forming units | eng |
| dc.subject | Kllebsiella pnuemoniae | eng |
| dc.title | Estudio de bacteriófagos como modelo de terapia antimicrobiana | spa |
| dc.type.driver | info:eu-repo/semantics/bachelorThesis | eng |
| dc.type.spa | Trabajo de grado - pregrado | spa |
| oaire.version | info:eu-repo/semantics/acceptedVersion | eng |
| sb.programa | Medicina | spa |
| sb.sede | Sede Barranquilla | spa |
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