Estudio piloto sobre los potenciales efectos genotóxicos y citotóxicos asociados a la tinta de tatuajes en jóvenes tatuados de la Universidad Simón Bolívar sede Barranquilla
dc.contributor.author | Rico Camacho, Edwin Junior | |
dc.date.accessioned | 2019-10-15T19:41:03Z | |
dc.date.available | 2019-10-15T19:41:03Z | |
dc.date.issued | 2019 | |
dc.description.abstract | Los tatuajes son dibujos o mensajes realizados sobre la piel de las personas. Algunos de los componentes de las tintas son considerados mutagénicos y carcinogénicos, sin embargo, no existen estudios que permitan analizar el posible efecto toxico de las tintas de tatuajes. El objetivo de la presente investigación es evaluar los potenciales efectos genotóxicos y citotóxicos asociados a la tinta de tatuajes jóvenes tatuados de la Universidad Simón Bolívar sede Barranquilla. La muestra de estudio fueron 30 hombres tatuados y 15 hombres no tatuados (controles). Se utilizó en ensayo de citoma de micronúcleo con bloqueo de citocinesis como método para analizar genotoxicidad y citotoxicidad de las tintas. La frecuencia de Micronúcleos, puentes nucleoplasmáticos y brote nuclear en personas tatuadas fue de 0.8, 0.25 y 0.15 respectivamente. Por otro lado, la frecuencia de necrosis y apoptosis fue de 0.1 y 0.62. aunque los resultados estadísticamente no fueron significativos, el ensayo de citoma de micronúcleo con bloqueo de citocinesis puede ser tenido en cuenta como una alternativa para analizar el potencial toxico de las tintas de tatuajes. | spa |
dc.description.abstract | Tattoos are drawings or messages made on people's skin. Some of the components of the inks are considered mutagenic and carcinogenic, however, there are no studies to analyze the possible toxic effect of tattoo inks. The objective of the present investigation is to evaluate the potential genotoxic and cytotoxic effects associated with the tattoo of young tattooed tattoos of the Simón Bolívar University, Barranquilla headquarters. The study sample was 30 tattooed men and 15 non-tattooed men (controls). It was used in a micronucleus cytoma assay with cytokinesis blockade as a method to analyze genotoxicity and cytotoxicity of the inks. The frequency of Micronuclei, nucleoplasmic bridges and nuclear outbreak in tattooed persons was 0.8, 0.25 and 0.15 respectively. On the other hand, the frequency of necrosis and apoptosis was 0.1 and 0.62. Although the results were not statistically significant, the micronucleus cytoma assay with cytokinesis blockade can be taken into account as an alternative to analyze the toxic potential of tattoo inks. | eng |
dc.identifier.uri | https://hdl.handle.net/20.500.12442/4130 | |
dc.language.iso | spa | spa |
dc.publisher | Ediciones Universidad Simón Bolívar | spa |
dc.publisher | Facultad de Ciencias Básicas y Biomédicas | spa |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | eng |
dc.rights.accessrights | info:eu-repo/semantics/restrictedAccess | spa |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.source.bibliographicCitation | Laux P, Tralau T, Tentschert J, Blume A, Dahouk S Al, Bäumler W, et al. A medical-toxicological view of tattooing. Lancet. 2015;387(10016):395–402. | eng |
dc.source.bibliographicCitation | Jacobsen E, Tønning K, Pedersen E, Bernth N, Serup J, Høgsberg T, et al. Chemical Substances in Tattoo Ink. [Internet]. 2012. 116 p. Available from: https://www2.mst.dk/udgiv/publications/2012/03/978-87-92779-87-8.pdf | eng |
dc.source.bibliographicCitation | Ministry of Health. Survey of Selected Samples of Tattoo Inks for the Presence of Heavy Metals. 2013; | eng |
dc.source.bibliographicCitation | Chimenos E, Batlle I, Velásquez S, Carcía T, Viñals H, Roselló X. Estética y cultura: patología bucal asociada a ciertas modas “actuales” (tatuajes, perforaciones bucales, etc.). Med Oral. 2003;8(1):197–206. | spa |
dc.source.bibliographicCitation | Forte G, Petrucci F, Cristaudo A, Bocca B. Market survey on toxic metals contained in tattoo inks. Sci Total Environ [Internet]. 2009;407(23):5997–6002. Available from: http://dx.doi.org/10.1016/j.scitotenv.2009.08.034 | eng |
dc.source.bibliographicCitation | Fornes B, Díez P, Sierra C. Complicaciones y cuidados de los piercings y los tatuajes (2a parte). ENFERMERÍAdermatológica. 2011;13(14):22–8. | spa |
dc.source.bibliographicCitation | Deschesnes M, Demers S, Finès P. Prevalence and characteristics of body piercing and tattooing among high school students. Can J Public Heal. 2006;94(4):325–9. | eng |
dc.source.bibliographicCitation | Laumann A, Derick A. Tattoos and body piercings in the United States: A national data set. J Am Acad Dermatol. 2006;55(3):413–21. | eng |
dc.source.bibliographicCitation | Timko A, Miller C, Johnson F, Ross V. In Vitro Quantitative Chemical Analysis of Tattoo Pigments. Arch Dermatol [Internet]. 2001;137(2):143–7. Available from: http://archderm.jamanetwork.com/article.aspx?articleid=478205 | eng |
dc.source.bibliographicCitation | Eghbali K, Mousavi Z, Ziarati P. Determination of heavy metals in Tattoo Ink. 2014;8(5):7121. | eng |
dc.source.bibliographicCitation | Cuyper C, Perez M. Dermatologic Complications with Body Art. 2010. 13–29 p. | eng |
dc.source.bibliographicCitation | Kluger N, Koljonen V. Tattoos, inks, and cancer. Lancet Oncol [Internet]. 2012;13(4):e161–8. Available from: http://dx.doi.org/10.1016/S1470-2045(11)70340-0 | eng |
dc.source.bibliographicCitation | Neale P, Stalter D, Tang J, Escher B. Bioanalytical evidence that chemicals in tattoo ink can induce adaptive stress responses. J Hazard Mater [Internet]. 2015;296:192–200. Available from: http://dx.doi.org/10.1016/j.jhazmat.2015.04.051 | eng |
dc.source.bibliographicCitation | Mataix J, Silvestre J. Reacciones cutáneas adversas por tatuajes y piercings. Actas Dermosifiliogr. 2009;100(8):643–56. | spa |
dc.source.bibliographicCitation | Castro A, Aragonés J. El tatuaje y su relación con características personales y sociales. PSICUMEX. 2017;6(2):50–65. | spa |
dc.source.bibliographicCitation | Ruby R, Kirby W, Maibach H. Cutaneous allergic reactions to tattoo ink. J Cosmet Dermatol. 2009;8:295–300. | spa |
dc.source.bibliographicCitation | Kazandjieva J, Tsankov N. Tattoos: dermatological complications. Clin Dermatol. 2007;25(4):375–82. | eng |
dc.source.bibliographicCitation | Kaatz M, Elsner P, Bauer A. Body-modifying concepts and dermatologic problems: tattooing and piercing. Clin Dermatol. 2008;26(1):35–44. | eng |
dc.source.bibliographicCitation | Otero M, Hermida M, Rodríguez G, Della P, García S, Cabrera H. Tatuajes. Arch Argentino Dermatología [Internet]. 2006;56:209–17. Available from: http://archivosdermato.org.ar/Uploads/Arch. Argent. Dermatol. 56 209-217, 2006.pdf | spa |
dc.source.bibliographicCitation | Adams D, Badreshia S, Ammirati C. A violaceous plaque. J Am Acad Dermatol. 2006;54:185–7. | eng |
dc.source.bibliographicCitation | Islam P, Chang C, Selmi C, Generali E, Huntley A, Teuber S, et al. Medical complications of tattoos: A comprehensive review. Clin Rev Allergy Immunol. 2016;50(2):273–86. | eng |
dc.source.bibliographicCitation | Kluger N. Acute complications of tattooing presenting in the ED. Am J Emerg Med [Internet]. 2012;30(9):2055–63. Available from: http://dx.doi.org/10.1016/j.ajem.2012.06.014 | spa |
dc.source.bibliographicCitation | U.S. Food and Drug Administration. Think Before You Ink: Are Tattoos Safe? 2009. | eng |
dc.source.bibliographicCitation | Falconi M, Teti G, Zago M, Galanzi A, Breschi L, Pelotti S, et al. Influence of a commercial tattoo ink on protein production in human fibroblasts. Arch Dermatol Res. 2009;301(7):539–47. | eng |
dc.source.bibliographicCitation | Regensburger J, Lehner K, Maisch T, Vasold R, Santarelli F, Engel E, et al. Tattoo inks contain polycyclic aromatic hydrocarbons that additionally generate deleterious singlet oxygen. Exp Dermatol. 2010;19(8):275–81. | eng |
dc.source.bibliographicCitation | Wamer W, Yin J-J. Photocytotoxicity in human dermal fibroblasts elicited by permanent makeup inks containing titanium dioxide. J Cosmet Sci. 2011;62(6):535–547. | eng |
dc.source.bibliographicCitation | Pinheiro R, Corrêa T, Biude T, Luiz P, Nakano B, Tiemi E, et al. Using the comet and micronucleus assays for genotoxicity studies: A review. Biomed Pharmacother. 2015;72:74–82. | eng |
dc.source.bibliographicCitation | Fenech M. Cytokinesis-block micronucleus cytome assay. Nat Protoc. 2007;2(5):1084–104. | eng |
dc.source.bibliographicCitation | Zalacain M, Sierrasesúmaga L, Patiño A. El ensayo de micronúcleos como medida de inestabilidad genética inducida por agentes genotóxicos. An Sist Sanit Navar. 2005;28(2):227–36. | spa |
dc.source.bibliographicCitation | Fenech M, Kirsch-Volders M, Natarajan A, Surralles J, Crott J, Norppa H, et al. Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells. Mutagenesis. 2011;26(1):125–32. | eng |
dc.source.bibliographicCitation | Mateuca R, Lombaert N, Aka P, Decordier I, Kirsch-Volders M. Chromosomal changes: induction, detection methods and applicability in human biomonitoring. Biochimie. 2006;88:1515–31. | eng |
dc.source.bibliographicCitation | Hoffelder D, Luo L, Burke N, Watkins S, Gollin S, Saunders W. Resolution of anaphase bridges in cancer cells. Chromosoma. 2004;112(8):389–97. | eng |
dc.source.bibliographicCitation | Murnane J. Telomeres and chromosome instability. DNA Repair (Amst). 2006;5(9–10):1082–92. | eng |
dc.source.bibliographicCitation | DeFilipps RA, Krupnick GA. The medicinal plants of Myanmar. PhytoKeys [Internet]. 2018;102:1–341. Available from: https://phytokeys.pensoft.net/articles.php?id=24380 | eng |
dc.source.bibliographicCitation | Fenech M, Chang W, Kirsch-Volders M, Holland N, Bonassi S, Zeiger E. Project: Detailed Description of the Scoring Criteria for the Cytokinesis-Block Micronucleus Assay Using Isolated Human Lymphocyte Cultures. Mutat Res. 2003;534:65–75. | eng |
dc.source.bibliographicCitation | Fenech M, Bonassi S. The effect of age, gender, diet and lifestyle on DNA damage measured using micronucleus frequency in human peripheral blood lymphocytes. Mutagenesis. 2011;26(1):43–9. | eng |
dc.source.bibliographicCitation | Pérez A. Cuerpos tatuados, “almas” tatuadas: nuevas formas de subjetividad en la contemporaneidad. Rev Colomb Antropol. 2009;45(1):69–94. | spa |
dc.source.bibliographicCitation | Gajski G, Gerić M, Oreščanin V, Garaj-Vrhovac V. Cytokinesis-block micronucleus cytome assay parameters in peripheral blood lymphocytes of the general population: Contribution of age, sex, seasonal variations and lifestyle factors. Ecotoxicol Environ Saf. 2018;148(July 2017):561–70. | eng |
dc.source.bibliographicCitation | Santovito A, Cervella P, Delpero M. Evidence of genotoxicity in lymphocytes of non-smoking alcoholics. Mol Biol Rep. 2015;42(1):53–9. | eng |
dc.source.bibliographicCitation | Gata V. Evidencia de la asociación entre cáncer colorrectal y la ingesta de carnes procesadas. Nutr Clin y Diet Hosp. 2017;37(2):69–74. | spa |
dc.source.bibliographicCitation | Gonzalez H, Moreno A, Quintana M. Efecto genotóxico de las mezclas complejas de hidrocarburos en trabajadores de estaciones de servicio de gasolina. Salud Uninorte. 2015;31(1):91–100. | spa |
dc.source.bibliographicCitation | Shaikh A, Barot D, Chandel D. Genotoxic effects of exposure to gasoline fumes on petrol pump workers. Int J Occup Environ Med. 2018;9(2):79–87. | eng |
dc.source.bibliographicCitation | Banerjee S, Singh N, Sreedhar G, Mukherjee S. Analysis of the genotoxic effects of mobile phone radiation using buccal micronucleus assay: A comparative evaluation. J Clin Diagnostic Res. 2016;10(3):82–5. | eng |
dc.source.bibliographicCitation | Cossio M, Giesen L, Araya G, Pérez M. Asociación entre tatuajes, perforaciones y conductas de riesgo en adolescentes. Rev Med Chil. 2012;140(2):198–206. | spa |
dc.source.bibliographicCitation | Carbajosa J. Efectos indeseables de la aplicación de piercings y tatuajes. Dermatologia Rev Mex. 2009;53(5):219–24. | spa |
dc.source.bibliographicCitation | Ballén J, Castillo J. La Práctica Del Tatuaje Y La Imagen Corporal. Rev Iberoam Psicol Cienc y Tecnol. 2015;8(1):103–9. | spa |
dc.source.bibliographicCitation | Forte G, Petrucci F, Cristaudo A, Bocca B. Quantification of Sensitizing Metals in Tattooing Pigments by SF-ICP-MS Technique. Open Chem Biomed Methods J. 2009;2(2):42–7. | spa |
dc.source.bibliographicCitation | Lehner K, Santarelli F, Vasold R, Penning R, Sidoroff A, König B, et al. Black tattoos entail substantial uptake of genotoxicpolycyclic aromatic hydrocarbons (PAH) in human skin and regional lymph nodes. PLoS One. 2014;9(3). | eng |
dc.subject | Tintas | spa |
dc.subject | Tatuajes | spa |
dc.subject | Genotoxicidad | spa |
dc.subject | Citotoxicidad | spa |
dc.subject | Piel | spa |
dc.subject | Inks | eng |
dc.subject | Tattoos | eng |
dc.subject | Genotoxicity | eng |
dc.subject | Cytotoxicity | eng |
dc.subject | Skin | eng |
dc.title | Estudio piloto sobre los potenciales efectos genotóxicos y citotóxicos asociados a la tinta de tatuajes en jóvenes tatuados de la Universidad Simón Bolívar sede Barranquilla | spa |
dc.type | Other | spa |
sb.programa | Maestría en Genética | spa |
sb.sede | Sede Barranquilla | spa |
Archivos
Bloque de licencias
1 - 1 de 1
No hay miniatura disponible
- Nombre:
- license.txt
- Tamaño:
- 1.71 KB
- Formato:
- Item-specific license agreed upon to submission
- Descripción: