Estudio piloto sobre los potenciales efectos genotóxicos y citotóxicos asociados a la tinta de tatuajes en jóvenes tatuados de la Universidad Simón Bolívar sede Barranquilla

dc.contributor.authorRico Camacho, Edwin Junior
dc.date.accessioned2019-10-15T19:41:03Z
dc.date.available2019-10-15T19:41:03Z
dc.date.issued2019
dc.description.abstractLos tatuajes son dibujos o mensajes realizados sobre la piel de las personas. Algunos de los componentes de las tintas son considerados mutagénicos y carcinogénicos, sin embargo, no existen estudios que permitan analizar el posible efecto toxico de las tintas de tatuajes. El objetivo de la presente investigación es evaluar los potenciales efectos genotóxicos y citotóxicos asociados a la tinta de tatuajes jóvenes tatuados de la Universidad Simón Bolívar sede Barranquilla. La muestra de estudio fueron 30 hombres tatuados y 15 hombres no tatuados (controles). Se utilizó en ensayo de citoma de micronúcleo con bloqueo de citocinesis como método para analizar genotoxicidad y citotoxicidad de las tintas. La frecuencia de Micronúcleos, puentes nucleoplasmáticos y brote nuclear en personas tatuadas fue de 0.8, 0.25 y 0.15 respectivamente. Por otro lado, la frecuencia de necrosis y apoptosis fue de 0.1 y 0.62. aunque los resultados estadísticamente no fueron significativos, el ensayo de citoma de micronúcleo con bloqueo de citocinesis puede ser tenido en cuenta como una alternativa para analizar el potencial toxico de las tintas de tatuajes.spa
dc.description.abstractTattoos are drawings or messages made on people's skin. Some of the components of the inks are considered mutagenic and carcinogenic, however, there are no studies to analyze the possible toxic effect of tattoo inks. The objective of the present investigation is to evaluate the potential genotoxic and cytotoxic effects associated with the tattoo of young tattooed tattoos of the Simón Bolívar University, Barranquilla headquarters. The study sample was 30 tattooed men and 15 non-tattooed men (controls). It was used in a micronucleus cytoma assay with cytokinesis blockade as a method to analyze genotoxicity and cytotoxicity of the inks. The frequency of Micronuclei, nucleoplasmic bridges and nuclear outbreak in tattooed persons was 0.8, 0.25 and 0.15 respectively. On the other hand, the frequency of necrosis and apoptosis was 0.1 and 0.62. Although the results were not statistically significant, the micronucleus cytoma assay with cytokinesis blockade can be taken into account as an alternative to analyze the toxic potential of tattoo inks.eng
dc.identifier.urihttps://hdl.handle.net/20.500.12442/4130
dc.language.isospaspa
dc.publisherEdiciones Universidad Simón Bolívarspa
dc.publisherFacultad de Ciencias Básicas y Biomédicasspa
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacionaleng
dc.rights.accessrightsinfo:eu-repo/semantics/restrictedAccessspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
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dc.subjectTintasspa
dc.subjectTatuajesspa
dc.subjectGenotoxicidadspa
dc.subjectCitotoxicidadspa
dc.subjectPielspa
dc.subjectInkseng
dc.subjectTattooseng
dc.subjectGenotoxicityeng
dc.subjectCytotoxicityeng
dc.subjectSkineng
dc.titleEstudio piloto sobre los potenciales efectos genotóxicos y citotóxicos asociados a la tinta de tatuajes en jóvenes tatuados de la Universidad Simón Bolívar sede Barranquillaspa
dc.typeOtherspa
sb.programaMaestría en Genéticaspa
sb.sedeSede Barranquillaspa

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