Glomerular Diseases in the Colombian Caribbean: Data from the Colombian Nephropathy Registry (NEFRORED®)
Cargando...
Archivos
Fecha
2022
Autores
Aroca-Martínez, Gustavo
González-Torres, Henry J.
Domínguez-Vargas, Alex
García- Tolosa, Raúl
Castillo-Parodi, Luis
Conde-Manotas, Juan
Navarro-Quiroz, Elkin
Acuña- Freyte, Andersson
Depine, Santos Ángel
Cadena-Bonfanti, Andrés
Título de la revista
ISSN de la revista
Título del volumen
Editor
Wolters Kluwer
Resumen
Our study aimed to describe the glomerular diseases, both primary glomerular
disease (PGD) and secondary glomerular disease (SGD) in the Colombian Caribbean based on the
first regional Colombian Nephropathy Registry (NEFRORED®). A descriptive and retrospective
study of adult patients with glomerular diseases from the Colombian Caribbean region was made.
All diagnoses by renal biopsy with light microscopy and immunofluorescence obtained between
January 2008 and June 2018 were recorded. Eight hundred and seventy-one renal biopsies were
obtained. The main clinical indication for biopsy was nephritic syndrome (36%). SGD was more
frequent than PGD (55% vs. 45%). Within SGD group, lupus nephritis (LN) was the most frequent
etiology (83%). Within PGD group, membranous nephropathy (33%) and focal segmental
glomerulosclerosis (FSGS) (19%) were the most common glomerular diseases. At a 24-month
follow-up, the patients with FSGS and paraproteinemia-mediated glomerular disease had the worst
renal survival prognosis. This is the first Colombian Nephropathy Registry in a Caribbean
population, demonstrating a high predominance of SGD due to LN.