Glomerular Diseases in the Colombian Caribbean: Data from the Colombian Nephropathy Registry (NEFRORED®)

Aroca-Martínez, Gustavo; González-Torres, Henry J.; Domínguez-Vargas, Alex; García- Tolosa, Raúl; Castillo-Parodi, Luis; Conde-Manotas, Juan; Navarro-Quiroz, Elkin; Acuña- Freyte, Andersson; Depine, Santos Ángel; Cadena-Bonfanti, Andrés; Musso, Carlos G.

Glomerular Diseases in the Colombian Caribbean: Data from the Colombian Nephropathy Registry (NEFRORED®)

Archivos

PDF.pdf (287.55 KB)

Fecha

2022

Autores

Aroca-Martínez, Gustavo

González-Torres, Henry J.

Domínguez-Vargas, Alex

García- Tolosa, Raúl

Castillo-Parodi, Luis

Conde-Manotas, Juan

Navarro-Quiroz, Elkin

Acuña- Freyte, Andersson

Depine, Santos Ángel

Cadena-Bonfanti, Andrés

Editor

Wolters Kluwer

Resumen

Our study aimed to describe the glomerular diseases, both primary glomerular disease (PGD) and secondary glomerular disease (SGD) in the Colombian Caribbean based on the first regional Colombian Nephropathy Registry (NEFRORED®). A descriptive and retrospective study of adult patients with glomerular diseases from the Colombian Caribbean region was made. All diagnoses by renal biopsy with light microscopy and immunofluorescence obtained between January 2008 and June 2018 were recorded. Eight hundred and seventy-one renal biopsies were obtained. The main clinical indication for biopsy was nephritic syndrome (36%). SGD was more frequent than PGD (55% vs. 45%). Within SGD group, lupus nephritis (LN) was the most frequent etiology (83%). Within PGD group, membranous nephropathy (33%) and focal segmental glomerulosclerosis (FSGS) (19%) were the most common glomerular diseases. At a 24-month follow-up, the patients with FSGS and paraproteinemia-mediated glomerular disease had the worst renal survival prognosis. This is the first Colombian Nephropathy Registry in a Caribbean population, demonstrating a high predominance of SGD due to LN.