Novel Biomarkers of Diabetic Kidney Disease
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Fecha
2023
Autores
Rico-Fontalvo, Jorge
Aroca-Martínez, Gustavo
Daza-Arnedo, Rodrigo
Cabrales, José
Rodríguez-Yánez, Tomás
Cardona-Blanco, María
Montejo-Hernández, Juan
Rodelo Barrios, Dairo
Patiño-Patiño, Jhonny
Osorio Rodríguez, Elber
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MDPI
Resumen
Diabetic kidney disease (DKD) is a highly prevalent condition worldwide. It represents
one of the most common complications arising from diabetes mellitus (DM) and is the leading cause
of end-stage kidney disease (ESKD). Its development involves three fundamental components: the
hemodynamic, metabolic, and inflammatory axes. Clinically, persistent albuminuria in association
with a progressive decline in glomerular filtration rate (GFR) defines this disease. However, as
these alterations are not specific to DKD, there is a need to discuss novel biomarkers arising from
its pathogenesis which may aid in the diagnosis, follow-up, therapeutic response, and prognosis of
the disease.
Descripción
Palabras clave
Biomarkers, Diabetic kidney disease, Pathogenesis, Diabetes mellitus
Citación
Rico-Fontalvo, J.; Aroca-Martínez, G.; Daza-Arnedo, R.; Cabrales, J.; Rodríguez-Yanez, T.; Cardona-Blanco, M.; Montejo- Hernández, J.; Rodelo Barrios, D.; Patiño-Patiño, J.; Osorio Rodríguez, E. Novel Biomarkers of Diabetic Kidney Disease. Biomolecules 2023, 13, 633. https://doi.org/10.3390/ biom13040633
