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Eficacia de una crema lipolítica en un tratamiento de sobrepeso y obesidad

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dc.contributor.authorKalmar, Isaac
dc.contributor.authorCortés-Castell, Ernesto
dc.contributor.authorRizo-Baeza, Mercedes
dc.contributor.authorConsuegra, José Rafael
dc.contributor.authorJiménez-Cabas, Javier
dc.date.accessioned2019-10-18T14:51:57Z
dc.date.available2019-10-18T14:51:57Z
dc.date.issued2019
dc.description.abstractObjetivo. Evaluar la eficacia coadyuvante de una combinación de ingredientes cosméticos en forma de crema lipolítica con dieta hipocalórica y actividad física comparada con dieta hipocalórica y actividad física para el tratamiento del sobrepeso y la obesidad en pacientes. Material y métodos. Se realizó un estudio monocéntrico, abierto y aleatorizado de grupos paralelos de 102 pacientes que consultaron a un centro de nutrición médico-clínico para el tratamiento del sobrepeso y la obesidad. Los perímetros de altura, brazo, cintura, cadera y muslo y el análisis de la composición corporal segmentaria con un equipo de impedancia se estudiaron en pacientes de 18 a 99 años de ambos sexos con asistencia voluntaria y con presencia de sobrepeso u obesidad durante un período de 16 semanas consecutivas. Los datos se analizaron estadísticamente comparando los valores iniciales y finales de todos los valores en ambos grupos. La seguridad fue monitoreada por la incidencia de eventos adversos. Un valor de p<0,001 fue considerado como de significación estadística. Resultados. Del total de 102 pacientes, se aplicaron los criterios de inclusión y exclusión; se incluyeron y analizaron 45 y 47 casos, respectivamente. La edad oscila entre 39,16 y 42,09 años (p = 0,246); el peso inicial 85,9 kg vs 85,08 kg (p = 0,810); perímetros: cintura inicial de 100,4 cm frente a 99,7 cm (p = 0,826); brazo inicial de 32,9 cm vs 33,4 cm (p = 0,453); cadera inicial: 108,6cm vs 107,7 (p = 0,666). Peso final 82,6 kg vs 78,7 kg (p = 0,227); perímetros: cintura final de 94,9 cm frente a 90,9 cm (p = 0,144); brazo final de 31,8 cm frente a 31,4 cm (p = 0,453); Cadera final: 106,7 cm vs 102,1 (p = 0,074). No hubo ningún informe de efectos secundarios no deseados con el uso de crema lipolítica, presentando una buena aceptabilidad. Los pacientes con crema lipolítica como adyuvante en el tratamiento del sobrepeso u obesidad perdieron mayor IMC, mayor porcentaje de peso y mayor porcentaje de grasa (p<0,001).spa
dc.description.abstractObjective. To evaluate the coadyouvant efficacy of a combination of cosmetics ingredients in the form of a lipolytic cream with hypocaloric diet and physical activity and compared with hypocaloric diet and physical activity for overweight and obesity treatment in patients. Material and methods. It was conducted a monocentric, open-label, randomized study of parallel groups of 102 patients that consulted in a medical-clinical nutrition center for overweight and obesity treatment. Height, arm, waist, hip and thigh perimeters and the analysis of segmental body composition with an impedance team were studied in patients between 18 and 99 years, of both sexes with voluntary attendance and with presence of overweight or obesity during a period of 16 consecutive weeks. The data were statistically analyzed by comparing the initial and final values of all the values in both groups. Safety was monitored by the incidence of adverse events. A value of p<0.001 was considered as statistical significance. Results. Of the total of 102 patients, the inclusion and exclusion criteria were applied; 45 and 47 cases are included and analyzed respectively. The age ranges between 39.16 vs 42.09 years (p = 0.246); initial weight 85.9 kg vs 85.08 kg (p = 0.810); perimeters: initial waist of 100.4cm vs 99.7cm (p = 0.826); initial arm of 32.9cm vs 33.4cm (p = 0.453); initial hip: 108.6cm vs 107.7 (p = 0.666). Final weight 82.6 kg vs 78.7 kg (p = 0.227); perimeters: final waist of 94.9 cm vs 90.9 cm (p = 0.144); final arm of 31.8 cm vs 31.4 cm (p = 0.453); final hip: 106.7 cm vs 102, 1 (p = 0.074). There was no report of unwanted side effects with the use of lipolytic cream, presented good acceptability. Patients with lipolytic cream as adjuvant in the treatment of overweight or obesity lose greater BMI, greater percentage of weight and greater percentage of fat (p <0.001). Conclusion. Patients with lipolytic cream as adjuvant in the treatment of overweight or obesity lose greater BMI, greater percentage of weight and greater percentage of fat.eng
dc.identifier.issn26107988
dc.identifier.urihttps://hdl.handle.net/20.500.12442/4172
dc.language.isospaspa
dc.publisherSociedad Venezolana de Farmacología Clínica y Terapéuticaspa
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.sourceRevista AVFT-Archivos Venezolanos de Farmacología y Terapéuticaspa
dc.sourceVol. 38 No. 2 (2019)spa
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dc.source.urihttp://www.revistaavft.com/images/revistas/2019/avft_3_2019/9_eficacia.pdfspa
dc.subjectLipólisisspa
dc.subjectCrema para la pielspa
dc.subjectObesidadspa
dc.subjectSobrepesospa
dc.subjectLipolysiseng
dc.subjectSkin creameng
dc.subjectObesityeng
dc.subjectOverweighteng
dc.titleEficacia de una crema lipolítica en un tratamiento de sobrepeso y obesidadspa
dc.title.alternativeEfficacy of a lipolytic cream in an overweight and obesity treatmenteng
dc.typearticlespa

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