En busqueda del hipnótico ideal: tratamiento farmacológico del insomnio

dc.contributor.authorChávez, Mervin
dc.contributor.authorNava, Manuel
dc.contributor.authorPalmar, Jim
dc.contributor.authorMartínez, María Sofía
dc.contributor.authorGraterol Rivas, Modesto
dc.contributor.authorContreras, Julio
dc.contributor.authorHernández, Juan Diego
dc.contributor.authorBermúdez, Valmore
dc.date.accessioned2018-03-23T15:25:39Z
dc.date.available2018-03-23T15:25:39Z
dc.date.issued2017
dc.description.abstractEl insomnio es un trastorno del sueño caracterizado por dificultad para la conciliación o mantenimiento del sueño, por disminución del tiempo, fragmentación o mala calidad del sueño, y sensación de cansancio al día siguiente. Se trata de un problema con gran prevalencia en países industrializados y representa uno de los motivos de consulta más frecuente en atención primaria. Su terapéutica incluye medidas farmacológicas y no farmacológicas. Las drogas hipnóticas incluyen un amplio rango de moléculas, como benzodiacepinas, compuestos Z, antidepresivos, antihistamínicos, entre otros, cada una con propiedades farmacodinámicas y farmacocinéticas particulares. Basada en evidencia clínica-epidemiológica, esta revisión discute la eficacia y seguridad de los fármacos hipnóticos, con el objetivo de establecer el prototipo de hipnótico ideal para cada tipo de insomnio, considerando las necesidades o condiciones del paciente.spa
dc.description.abstractInsomnia is a sleep disorder characterized by difficulty for the onset or maintenance of sleep, as well as shortening, fragmentation or bad quality of sleep, and feeling unrested the following day. Insomnia boasts a high prevalence in industrialized countries, and represents one of the most frequent chief complaints in primary care. Treatment involves pharmacologic and non-pharmacologic measures. Hypnotic drugs include a wide range of molecules, such as benzodiazepines, z compounds, antidepressants, antihistamines and several others, each with distinct pharmacodynamic and pharmacokinetic properties. Based on clinical and epidemiologic evidence, this review discusses the efficacy and safety of hypnotic drugs, with the objective of establishing the prototype of the ideal hypnotic for each type of insomnia, according to the specific needs of each kind of patient.eng
dc.identifier.issn26107988
dc.identifier.urihttp://hdl.handle.net/20.500.12442/1916
dc.language.isospaspa
dc.publisherSociedad Venezolana de Farmacología Clínica y Terapéuticaspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.licenseLicencia de Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacionalspa
dc.sourceAVFT-Archivos Venezolanos de Farmacología y Terapéuticaspa
dc.sourceVol. 36, No.1 (2017)spa
dc.source.urihttp://www.revistaavft.com/images/revistas/2017/AVFT%201%202017/en%20busqueda%20del%20hipnotico%20ideal.pdf
dc.subjectInsomniospa
dc.subjectHipnótico idealspa
dc.subjectArquitectura del sueñospa
dc.subjectDrogas Zspa
dc.subjectBenzodiacepinasspa
dc.subjectInsomniaeng
dc.subjectIdeal hypnoticeng
dc.subjectSleep architectureeng
dc.subjectZ drugs,eng
dc.subjectBenzodiazepineseng
dc.titleEn busqueda del hipnótico ideal: tratamiento farmacológico del insomniospa
dc.title.alternativeSearching for the ideal hypnotic: pharmacological treatment of insomniaeng
dc.typearticlespa
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