WCN26-8271 Social vulnerability and lupus nephritis clustering in Barranquilla, Colombia: integrating clinical registry data with a population vulnerability index

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2026

Authors

Aroca, Maria-Paula
Aroca-Martinez, Gustavo
Depine, Santos
Camargo- Rodriguez, Kanery
Fontalvo Avila, Nicoll
Pérez-Jiménez, Valentina
Vasquez, Esteban
Cadena, Andres
Sarmiento, Joanny
Manjarres, Karen

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International Society of Nephrology ISN

Abstract

Introduction: Lupus nephritis (LN) is a severe manifestation of systemic lupus erythematosus (SLE), with its incidence and progression potentially influenced by structural socioeconomic inequalities. The Population Renal Health paradigm (Burgos-Calderón, Depine, and Aroca- Martínez, 2021) shifts from individual risk assessment to population and territorial vulnerability analysis by integrating social determinants of health (SDOH). To operationalize this approach, the Population Vulnerability Index (PVI) was developed as a quantitative geospatial tool that measures SDOH across the Colombian Caribbean region, enabling systematic comparison of territorial vulnerability. In parallel, the RENELUP registry collects and georeferences LN cases throughout Colombia. This study cross-references RENELUP data from the city of Barranquilla with PVI scores to examine how SDOH influence disease distribution patterns in this urban setting.

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