Prevalencia de infección concomitante de S. aureus y staphylofagos en trabajadores de unidades de cuidados intensivos del distrito de Barranquilla
datacite.rights | http://purl.org/coar/access_right/c_16ec | spa |
dc.contributor.advisor | Lozano Solano, Dayan | |
dc.contributor.author | Acuña Lombana, Alberto Mario | |
dc.contributor.author | Gutiérrez Salas, Leidys Dianis | |
dc.contributor.author | Rinaldy Potes, Otto Enrique | |
dc.date.accessioned | 2021-08-19T21:52:03Z | |
dc.date.available | 2021-08-19T21:52:03Z | |
dc.date.issued | 2019 | |
dc.description.abstract | Los bacteriófagos son virus de bacterias que, por su especificidad, son considerados hoy día como alternativas para el control de infecciones bacterianas. De igual forma han sido identificados en varios nichos humanos como en colon y piel, dejando en entredicho su rol como microbiota protectora. Por su parte Staphylococcus aureus es uno de los principales patógenos en humanos y animales, comúnmente aislado en unidad de cuidados intensivos (UCI), sin embargo, la tasa de infección versus colonización por S. aureus en el personal médico es baja. A pesar de que se ha descrito la presencia de los fagos como parte de la microbiota humana, no se ha esclarecido cuál es su rol como microbiota acompañante. El objetivo del presente trabajo fue determinar la colonización simultánea de S. aureus y Stafilofagos en muestras nasales de los trabajadores unidades de cuidados intensivos del distrito de Barranquilla. Se tomaron un total de 18 muestras nasales de trabajadores de salud en 6 Unidades de cuidados intensivos de 2 Instituciones prestadoras de salud de 4to nivel de atención. De los cuales el 67% (n=12) fueron positivos para S. aureus las cuales fueron confirmadas por la identificación del gen NUC que es especie específico. El 17% (n=2) positivos para Stafilofagos. De los aislamientos de S. aureus se determinó que el 58% (n=7) son resistentes a Meticilina (SARM) y el 8% (N=1) presenta la toxina PVL. | spa |
dc.description.abstract | Phages are viruses of bacteria that, due to their specificity, are considered as alternatives for the control of bacterial infections. In the same way they have been identified in several human niches as in colon and skin, leaving in between their role as a protective microbiome. On the other hand, Staphylococcus aureus is one of the main pathogens in humans and animals, commonly isolated in intensive care unit (ICU), however the rate of infection versus colonization by S. aureus in medical personnel is low. Although the presence of phages has been described as part of the human microbiome, its role as an accompanying microbiome has not been clarified. The objective of the present work was to determine the simultaneous colonization of S. aureus and Staphylococcus in nasal samples of the workers on intensive care units (ICU) of the district of Barranquilla. A total of 18 nasal samples of health workers were taken in 6 intensive care units from 2 health care institutions of the 4th level of care. Of which 67% (n = 12) were positive for S. aureus which were confirmed by the identification of the NUC gene that is specific species. 17% (n = 2) positive for staphylophages. Of the isolates of S. aureus, it was determined that 58% (n = 7) are resistant to Methicillin (MRSA) and 8% (N = 1) has the PVL toxin. | eng |
dc.format.mimetype | spa | |
dc.identifier.uri | https://hdl.handle.net/20.500.12442/8139 | |
dc.language.iso | spa | spa |
dc.publisher | Ediciones Universidad Simón Bolívar | spa |
dc.publisher | Facultad de Ciencias de la Salud | spa |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | eng |
dc.rights.accessrights | info:eu-repo/semantics/restrictedAccess | spa |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
dc.subject | Staphylococcus Aureus | spa |
dc.subject | UCI | spa |
dc.subject | Bacteriófagos | spa |
dc.subject | Bacterias | spa |
dc.subject | Colonización | spa |
dc.subject | Microbiota | spa |
dc.subject | Infecciones | spa |
dc.subject | Salud | spa |
dc.subject | ICU | eng |
dc.subject | Bacteriophages | eng |
dc.subject | Bacteria | eng |
dc.subject | Colonization | eng |
dc.subject | Microbiome | eng |
dc.subject | Infections | eng |
dc.subject | Health | eng |
dc.title | Prevalencia de infección concomitante de S. aureus y staphylofagos en trabajadores de unidades de cuidados intensivos del distrito de Barranquilla | spa |
dc.type.driver | info:eu-repo/semantics/bachelorThesis | spa |
dc.type.spa | Trabajo de grado - pregrado | spa |
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oaire.version | info:eu-repo/semantics/acceptedVersion | spa |
sb.programa | Medicina | spa |
sb.sede | Sede Barranquilla | spa |