Oral analogues of GLP-1: perspectives on glycemic control and cardiorenal risk in patients with type 2 diabetes mellitus
| datacite.rights | http://purl.org/coar/access_right/c_abf2 | |
| dc.contributor.author | Rico-Fontalvo, Jorge | |
| dc.contributor.author | daza arnedo, rodrigo andres | |
| dc.contributor.author | Vázquez Jiménez, Lourdes Carolina | |
| dc.contributor.author | Rodríguez-Yánez, Tomas | |
| dc.contributor.author | Raad Sarabia, Maria Isabel | |
| dc.contributor.author | TOAPANTA, NÉSTOR | |
| dc.contributor.author | Pérez, Rafael V. | |
| dc.contributor.author | Montejo-Hernández, Juan | |
| dc.contributor.author | Soler, María J. | |
| dc.date.accessioned | 2025-06-10T20:13:22Z | |
| dc.date.available | 2025-06-10T20:13:22Z | |
| dc.date.issued | 2024 | |
| dc.description.abstract | At present, type 2 diabetes mellitus (T2DM) is the leading cause of end-stage kidney disease. The management of T2DM in recent years has moved from a glucocentric approach to a global approach with the priority of introducing treatments that offer renal and cardiovascular protection. In this article, we review in depth the pharmacokinetics and pharmacodynamics of the first oral analog of glucagon-like peptide-1 (oral semaglutide) in comparison with its subcutaneous formulation. The knowledge and implementation of these drugs will be very useful in daily clinical practice | eng |
| dc.description.abstract | La diabetes mellitus tipo 2 (DM2) es la primera causa de inicio de terapia renal sustitutiva en la actualidad. El manejo de la DM2 en los últimos años ha pasado de un enfoque glucocéntrico a un enfoque global con la prioridad de la introducción de los tratamientos que ofrecen protección renal y cardiovascular. En este artículo revisamos en profundidad la farmacoci nética y farmacodinamia del primer análogo oral del péptido similar al glucagón-1 (semaglutide oral) en comparación con su formulación subcutánea. El conocimiento e implementación de dichos fármacos nos serán de gran utilidad en la práctica clínica habitual | spa |
| dc.format.mimetype | ||
| dc.identifier.doi | http://dx.doi.org/10.24875/NEFRO.M24000021 | |
| dc.identifier.issn | 24449032 (Electrónico) | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12442/16665 | |
| dc.identifier.url | https://www.nefrologialatinoamericana.com/frame_eng.php?id=120 | |
| dc.language.iso | eng | |
| dc.publisher | Sociedad Latinoamericana de Nefrología e Hipertensión | spa |
| dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | eng |
| dc.rights.accessrights | info:eu-repo/semantics/openAccess | |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.source | Nefrología Latinoamericana | spa |
| dc.source | Nefro Latinoam. | eng |
| dc.source | Vol. 21 No. 1, (2024) | spa |
| dc.subject | Diabetes mellitus | spa |
| dc.subject | Glucagon-like peptide 1 receptor analogs | spa |
| dc.subject | Semaglutide | spa |
| dc.subject.keywords | Diabetes Mellitus | eng |
| dc.subject.keywords | Análogos del receptor del péptido similar al glucagón tipo 1 | eng |
| dc.subject.keywords | Semaglutida | eng |
| dc.title | Oral analogues of GLP-1: perspectives on glycemic control and cardiorenal risk in patients with type 2 diabetes mellitus | eng |
| dc.title.translated | Análogos orales del GLP-1: perspectivas en el control glicémico y riesgo cardiorenal en pacientes con diabetes mellitus tipo 2 | spa |
| dc.type.driver | info:eu-repo/semantics/article | |
| dc.type.spa | Artículo científico | |
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| oaire.version | info:eu-repo/semantics/publishedVersion |