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Stevia rebaudiana Bertoni and Its Effects in Human Disease: Emphasizing Its Role in Inflammation, Atherosclerosis and Metabolic Syndrome

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dc.contributor.authorRojas, Edwardspa
dc.contributor.authorBermúdez, Valmorespa
dc.contributor.authorMotlaghzadeh, Yasamaneng
dc.contributor.authorMathew, Justineng
dc.contributor.authorFidilio, Enzamariaspa
dc.contributor.authorFaria, Judithspa
dc.contributor.authorRojas, Joselynspa
dc.contributor.authorCabrera de Bravo, Mayelaspa
dc.contributor.authorContreras, Juliospa
dc.contributor.authorMantilla, Linda Pamelaspa
dc.contributor.authorAngarita, Lisséspa
dc.contributor.authorSepúlveda, Paola Amarspa
dc.contributor.authorKuzmar, Isaacspa
dc.date.accessioned2019-07-18T23:41:43Z*
dc.date.available2019-07-18T23:41:43Z*
dc.date.issued2018
dc.description.abstractPurpose of Review. Stevia rebaudiana Bertoni is a perennial shrub with zero calorie content that has been increasing in popularity for its potential use as an adjuvant in the treatment of obesity. The level of evidence supporting general benefits to human health is insufficient. We conducted a review of the literature summarizing the current knowledge and role in human disease. Recent Findings. Despite stevia’s minimal systemic absorption, studies have been promising regarding its potential benefits against inflammation, carcinogenesis, atherosclerosis glucose control, and hypertension. On the other hand, the growing popularity of artificial sweeteners does not correlate with improved trends in obesity. An increased intake of artificial non-caloric sweeteners may not be associated with decreased intake of traditional sugar-sweetened beverages and foods. The effects of Stevia on weight change have been linked to bacteria in the intestinal microbiome, mainly by affecting Clostridium and Bacteroides sp. populations. A growing body of evidence indicates that Stevia rebaudiana Bertoni is protective against malignant conversion by inhibition of DNA replication in human cancer cell growth in vitro. Summary. Consumption of Stevia has demonstrated to be generally safe in most reports. Further clinical studies are warranted to determine if regular consumption brings sustained benefits for human health.spa
dc.identifier.issn21613311
dc.identifier.urihttps://hdl.handle.net/20.500.12442/3585
dc.language.isoengeng
dc.publisherSpringerspa
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.accessrightsinfo:eu-repo/semantics/embargoedAccessspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.sourceCurrent Nutrition Reportseng
dc.sourceSeptember 2018, Volume 7, Issue 3eng
dc.source.urihttps://doi.org/10.1007/s13668-018-0228-zeng
dc.subjectStevia rebaudiana Bertonieng
dc.subjectObesityeng
dc.subjectType 2 diabeteseng
dc.subjectHypertensioneng
dc.titleStevia rebaudiana Bertoni and Its Effects in Human Disease: Emphasizing Its Role in Inflammation, Atherosclerosis and Metabolic Syndromeeng
dc.typearticleeng
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