Frecuencia de anticuerpos treponémicos y no treponémicos para sífilis en poblaciones en riesgo de tres instituciones de salud del distrito de Barranquilla (Colombia)
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Fecha
2017
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Sociedad Venezolana de Farmacología Clínica y Terapéutica
Resumen
Introducción: la sífilis es una infección de transmisión sexual
con alta incidencia y prevalencia. En Colombia se vigila
la sífilis congénita y gestacional y no existen reportes oficiales
para la población general, ni para grupos a riesgo.
Objetivo: determinar la frecuencia de anticuerpos treponémicos
y no treponémicos y describir hábitos en pacientes de
tres instituciones de salud del distrito de Barranquilla, durante
los años 2014-2016.
Metodología: se realizó un estudio exploratorio, de campo
en 158 sujetos consumidores de sustancias psicoactivas,
infectados con VIH y habitantes en situación de calle. La recolección
de la información se realizó a través de un formato
de captura diseñado para el estudio, el cual se validó previamente.
Se determinó asociación entre variables sociodemográficas
y hábitos, con la presencia de anticuerpos treponémicos
(SD BIOLINE Syphilis3.0) y no treponémicos (VDRL).
La asociación entre ellas se determinó por Chi cuadrado de
independencia.
Resultados: la frecuencia de anticuerpos treponémicos fue
de 22,8%. Los individuos infectados con VIH registraron la
frecuencia más alta (41,7%). Se encontró asociación entre
la frecuencia de anticuerpos y las relaciones sexuales hombre
con hombre (p=0,0001), el no uso de condón durante
la compra de sexo (p=0,031) y el antecedente de consumo
de sustancias psicoactivas (p=0,029). Se evidencia que los
antecedentes de otras ITS como gonorrea (p=0,013) y VIH
(p=0,010), se encuentran asociadas a la infección con sífilis
Conclusión: se encontró alta frecuencia de anticuerpos contra
Treponema pallidum y factores de riesgos asociados a la
presencia de estos en la población estudiada.
Introduction: Syphilis is a sexual transmitted infection (STI) with high incidence and prevalence. In Colombia gestational and congenital syphilis are under surveillance but there are not official reports for general population, neither for population on risk. Objective: To determine the treponemic and non treponemic antibodies frequency as well to describe the infection risk behaviors on patients from three health institutes at Barranquilla district during 2014-2016 period. Methodology: A transversal descriptive study was conducted in 158 subjects in cluding psychoactive substances consumers, HIV infected and homeless condition individuals. The information was collected through a capture format designed for the study, which was previously validated. The association of socio-demographic variables and risk behaviors with treponemic (SD BIOLINE Syphilis 3.0) and non treponemic (VDRL) antibodies presence was made using chi-squared independence test. Results: The frequency of treponemic antibodies was 22.8%. The HIV infected individuals registered the highest frequency (41.7%). Association with antibodies frequency was found for: MSM (men who have sex with men) relationship (p=0,0001), non-use of condom during commercial sex purchase (p=0,031) and record of psychoactive consumption (p=0,029). The reis evidence that having reported previously STI slikegonorrhea (p=0,013) and HIV (p=0,010) are associated to syphilis infection. Conclusion: We found a high frequency of antibodies against Treponema pallidum and risk factors associated with the presence of these in the studied population.
Introduction: Syphilis is a sexual transmitted infection (STI) with high incidence and prevalence. In Colombia gestational and congenital syphilis are under surveillance but there are not official reports for general population, neither for population on risk. Objective: To determine the treponemic and non treponemic antibodies frequency as well to describe the infection risk behaviors on patients from three health institutes at Barranquilla district during 2014-2016 period. Methodology: A transversal descriptive study was conducted in 158 subjects in cluding psychoactive substances consumers, HIV infected and homeless condition individuals. The information was collected through a capture format designed for the study, which was previously validated. The association of socio-demographic variables and risk behaviors with treponemic (SD BIOLINE Syphilis 3.0) and non treponemic (VDRL) antibodies presence was made using chi-squared independence test. Results: The frequency of treponemic antibodies was 22.8%. The HIV infected individuals registered the highest frequency (41.7%). Association with antibodies frequency was found for: MSM (men who have sex with men) relationship (p=0,0001), non-use of condom during commercial sex purchase (p=0,031) and record of psychoactive consumption (p=0,029). The reis evidence that having reported previously STI slikegonorrhea (p=0,013) and HIV (p=0,010) are associated to syphilis infection. Conclusion: We found a high frequency of antibodies against Treponema pallidum and risk factors associated with the presence of these in the studied population.
Descripción
Palabras clave
Sífilis, Treponema pallidum, Anticuerpo, Reaginas, Syphilis, Antibody, Reagins