Validation of a score for the prediction of serious infection in patients with systemic lupus erythematosus: data from a latin american lupus cohort

Quintana, Rosana; Pons-Estel, Guillermo; Roberts, Karen; Palacios Santillán, Erika; Rúa-Figueroa, Iñigo; Pego-Reigosa, José M.; Ibañez, Pablo; Berbotto, Leonel Ariel; Bertolaccini, Maria Constanza; Micelli, Marina Laura; Pisoni, Cecilia; de Souza Barbosa, Vitalina; de Ataíde Mariz, Henrique; Machado Ribeiro, Francinne; P.C. Seguro, Luciana; Inoue Sato, Emilia; Mimica Davet, Milena; Aroca-Martinez, Gustavo; Bonilla-Abadía, Fabio; Quintana-López, Gerardo; Sánchez Briones, Reyna Elizabeth; Pérez Cristóbal, Mario; Silveira, Luis H.; García-De la Torre, Ignacio; Morales Avendaño, Ivan; Gámez Siller, Pablo; Paats Nicora, Astrid; Cieza Calderón, Jorge; Mendoza Maldonado, Andy Armando; Rebella, Martin; Silveira, Gonzalo; Jaramillo, John Fredy; Sánchez, Mónica; Sbarigia, Urbano; Orillion, Ashley; Zazzetti, Federico; Alarcón, Graciela S.; Pons-Estel, Bernardo

Validation of a score for the prediction of serious infection in patients with systemic lupus erythematosus: data from a latin american lupus cohort

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PDF.pdf (811.52 KB)

Fecha

2025

Autores

Quintana, Rosana

Pons-Estel, Guillermo

Roberts, Karen

Palacios Santillán, Erika

Rúa-Figueroa, Iñigo

Pego-Reigosa, José M.

Ibañez, Pablo

Berbotto, Leonel Ariel

Bertolaccini, Maria Constanza

Micelli, Marina Laura

Editor

Gladel

Resumen

Patients with systemic lupus erythematosus (SLE) are at increased risk of serious infections, which in turn, are associated with morbidity and mortality. The Systemic Lupus Erythematosus Registry of the Spanish Society of Rheumatology (RELESSER) group has developed and internally validated a tool for prediction of serious infections in SLE, with a recently improved version (SLE SI Score Revised or SLESIS-R), being an accurate and reliable instrument. SLESIS-R includes age, previous SLE-related hospitalization, previous serious infection, and glucocorticoid dose. This study aimed to validate SLESIS-R in a multi-ethnic, multi-national Latin-American (LA) SLE cohort.