Gestational diabetes and thyroid disorders in pregnant women in a specialized maternal-child diagnostic center
| datacite.rights | http://purl.org/coar/access_right/c_abf2 | eng |
| dc.contributor.author | Sierra-Castrillo, Jhoalmis | |
| dc.contributor.author | Perdomo Dominguez, Yojanna | |
| dc.contributor.author | Villamizar Carvajal, Jeferson Adrián | |
| dc.contributor.author | Muñoz-Bravo, Adriana | |
| dc.contributor.author | Gómez-Rave, Lyz Jenny | |
| dc.contributor.author | Bermúdez, Valmore | |
| dc.date.accessioned | 2023-08-17T18:57:08Z | |
| dc.date.available | 2023-08-17T18:57:08Z | |
| dc.date.issued | 2022 | |
| dc.description.abstract | Introduction: gestational diabetes mellitus (GDM) commonly appears between the second and third trimesters of pregnancy as a result of hormonal changes that induce a transitory state of insulin resistance (IR) in the mother, allowing a greater supply of glucose to the fetus. After GDM, thyroid disease is the most common endocrine disorder in obstetrics, with an incidence of 5-10%. Some studies speak of the existence of a relationship between diabetes and thyroid disorders (TA) but the results remain controversial, limiting the analysis of the effects that both diseases could have on the development of pregnancy. Therefore, the identification of patients at risk, prevention and timely treatment, constitute one of the priority issues in public health. Objective: in this study, the prevalence of GDM and AT in pregnant women attended in a specialized center for maternal and child diagnosis was analyzed. Materials and methods: retrospective research, based on the exploration of medical records in the period from 2016 to 2020, with a probabilistic sample of 388 pregnant women (n=388). For the diagnosis of GDM, the results of the O'sullivan test, oral glucose tolerance test (OGTT) and fasting blood glucose were taken into account. Thyroid alteration was identified from TSH values, but only 120 pregnant women reported results for this test (n=120). Descriptive measures and simple frequency distributions were calculated. To establish the relationship between GDM and AT, the chi-square test was applied with a statistical significance of p=0.05. Results:the prevalence of GDM was 10.6% (n=41) and of AT 17.5% (n=21). 19% of the pregnant women simultaneously presented GDM and AT with a predominance of a tendency to hyperthyroidism. No significant association was found between GDM and AT (p=0.537). Conclusion: This pilot study confirms that GDM and AT are conditions frequently present in pregnant women. Although there could be a risk of developing GDM in patients with AT, studies with a larger sample number are suggested to clarify this relationship. | eng |
| dc.description.abstract | Introducción: comúnmente la diabetes mellitus gestacio nal (DMG) suele aparecer entre el segundo y tercer trimes tre del embarazo como consecuencia de cambios hormo nales que inducen en la madre un estado transitorio de re sistencia a la insulina (IR), permitiendo un mayor aporte de glucosa al feto. Después de la DMG, la patología tiroidea es la alteración endocrina más frecuente en obstetricia, con una incidencia de 5-10%. Algunos estudios hablan de la existencia de una relación entre diabetes y alteración tiroidea (AT) pero los resultados siguen siendo controverti dos, limitando el análisis de los efectos que ambas enfer medades podrían tener en el desarrollo del embarazo. Por ello, la identificación de pacientes en riesgo, la prevención y el tratamiento oportuno, constituyen uno de los temas prioritarios en salud pública. Objetivo: en este estudio se analizó la prevalencia de DMG y de AT en gestantes aten didas en un centro especializado de diagnóstico materno infantil. Materiales y métodos: investigación retrospectiva, a partir de la exploración de historias clínicas en el periodo de 2016 al 2020, con una muestra probabilística de 388 gestantes (n=388). Para el diagnóstico de DMG se tuvier on en cuenta resultados del Test de O’sullivan, prueba de tolerancia oral a la glucosa (PTOG) y glucemia en ayunas. La alteración tiroidea se identificó a partir de valores de TSH, pero sólo 120 gestantes reportaron resultados para esta prueba (n=120). Se calcularon medidas descriptivas y distribuciones de frecuencia simple. Para establecer la relación entre DMG y AT se aplicó la prueba chi-cuadrado con una significancia estadística p=0,05. Resultados: la prevalencia de DMG fue del 10,6% (n=41) y de AT 17,5% (n=21). El 19% de las gestantes presentaron de mane ra simultánea DMG y AT con predominio de tendencia a hipertiroidismo. No se logró evidenciar asociación sig nificativa entre DMG y AT (p=0,537). Conclusión: este estudio piloto ratifica que la DMG y la AT son condiciones presentadas con frecuencia en gestantes. Aunque podría existir riesgo de desarrollo de DMG en paciente con AT, se sugieren estudios con mayor número de muestra que permitan esclarecer esta relación. | spa |
| dc.format.mimetype | spa | |
| dc.identifier.citation | Jhoalmis Sierra-Castrillo, Yojanna Perdomo Dominguez, Jeferson Adrian Villamizar Carvajal, Adriana Muñoz-Bravo, Lyz Jenny Gómez-Rave, & Valmore Bermudez. (2022). Gestational diabetes and thyroid disorders in pregnant women in a specialized maternal-child diagnostic center. https://doi.org/10.5281/zenodo.7415235 | eng |
| dc.identifier.doi | https://doi.org/10.5281/zenodo.7415235 | |
| dc.identifier.issn | 26107996 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12442/13155 | |
| dc.language.iso | eng | eng |
| dc.publisher | Sociedad Latinoamericana de Hipertensión | spa |
| dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 Internacional | eng |
| dc.rights.accessrights | info:eu-repo/semantics/openAccess | eng |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.source | Revista Latinoamericana de Hipertensión | spa |
| dc.source | Vol. 17, No. 6 (2022) | |
| dc.subject | Diabetes gestational | eng |
| dc.subject | Thyroid disease | eng |
| dc.subject | Pregnancy | eng |
| dc.subject | Prevalence | eng |
| dc.subject | Diabetes gestacional | spa |
| dc.subject | Enfermedades de la tiroides | spa |
| dc.subject | Embarazo | spa |
| dc.subject | Prevalencia | spa |
| dc.title | Gestational diabetes and thyroid disorders in pregnant women in a specialized maternal-child diagnostic center | eng |
| dc.title.translated | Diabetes gestacional y alteraciones tiroideas en gestantes de un centro especializado de diagnóstico materno-infantil | spa |
| dc.type.driver | info:eu-repo/semantics/article | eng |
| dc.type.spa | Artículo científico | spa |
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| oaire.version | info:eu-repo/semantics/publishedVersion | eng |