Análisis del citoma de células bucales y biomarcadores en orina de individuos expuestos a minería de carbón en la Loma-Cesar
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Fecha
2022
Autores
Pérez Pérez, José Dionisio
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Ediciones Universidad Simón Bolívar
Facultad de Ciencias Básicas y Biomédicas
Facultad de Ciencias Básicas y Biomédicas
Resumen
La minería de carbón en términos económicos es una fuente de empleo que proporciona una cantidad considerable de recursos económicos a los países que poseen grandes reservas de este mineral, lo desfavorable de las actividades mineras está en la contaminación que ocasiona el coctel de compuestos que son liberados al medio ambiente, los cuales tienen un impacto negativo sobre la salud humana.
El objetivo general de esta investigación fue analizar los biomarcadores de citotoxicidad, genotoxicidad, proliferación celular de células bucales y biomarcadores en orina de individuos crónicamente expuestos a minería de carbón en la Loma-Cesar. Para alcanzar los objetivo de esta investigación, se seleccionaron 70 personas expuestas a residuos de minería de carbón en el corregimiento de la Loma-Cesar y 70 personas no expuestas a residuos de carbón de la ciudad de Barranquilla (grupo control), ambos grupos se les aplicaron los criterios de inclusión y exclusión, los participantes seleccionados firmaron el consentimiento informado, diligenciaron un cuestionario con datos sociodemográficos y seguidamente se procedió con la toma de muestra.
Coal mining in economic terms is a source of employment that provides a considerable amount of economic resources to countries that have large reserves of this mineral, the disadvantage of mining activities is in the pollution caused by the cocktail of compounds that are released to the environment, which have a negative impact on human health. The general objective of this research was to analyze the biomarkers of cytotoxicity, genotoxicity, cellular proliferation of buccal cells and biomarkers in urine of individuals chronically exposed to coal mining in Loma-Cesar. To achieve the objective of this research, 70 people exposed to coal mining residues in the village of Loma-Cesar and 70 people not exposed to coal residues in the city of Barranquilla (control group) were selected; both groups were The inclusion and exclusion criteria were applied, the selected participants signed the informed consent, filled out a questionnaire with sociodemographic data, and then the sample was taken.
Coal mining in economic terms is a source of employment that provides a considerable amount of economic resources to countries that have large reserves of this mineral, the disadvantage of mining activities is in the pollution caused by the cocktail of compounds that are released to the environment, which have a negative impact on human health. The general objective of this research was to analyze the biomarkers of cytotoxicity, genotoxicity, cellular proliferation of buccal cells and biomarkers in urine of individuals chronically exposed to coal mining in Loma-Cesar. To achieve the objective of this research, 70 people exposed to coal mining residues in the village of Loma-Cesar and 70 people not exposed to coal residues in the city of Barranquilla (control group) were selected; both groups were The inclusion and exclusion criteria were applied, the selected participants signed the informed consent, filled out a questionnaire with sociodemographic data, and then the sample was taken.
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Palabras clave
Carbón, Riesgo, Residuos de minería, Daño oxidativo, ADN, Biomarcadores, Genotoxicidad, Coal, Risk, Mining residues, Oxidative damage, DNA, Biomarkers, Genotoxicity
