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Perirenal fat thickness is associated with metabolic risk factors in patients with chronic kidney disease

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dc.contributor.authorD´Marco, Luisspa
dc.contributor.authorSalazar, Juanspa
dc.contributor.authorCortez, Mariespa
dc.contributor.authorSalazar, Maríaspa
dc.contributor.authorWettel, Marjorieeng
dc.contributor.authorLima-Martínez, Marcosspa
dc.contributor.authorRojas, Edwardspa
dc.contributor.authorRoque, Willyspa
dc.contributor.authorBermúdez, Valmorespa
dc.date.accessioned2019-08-08T15:03:04Z
dc.date.available2019-08-08T15:03:04Z
dc.date.issued2019
dc.description.abstractAdipose tissue accumulation in specific body compartments has been associated with diabetes, hypertension and dyslipidemia. Perirenal fat (PRF) may lead to have direct lipotoxic effects on renal function and intrarenal hydrostatic pressure. This study was undertaken to explore the association of PRF with cardiovascular risk factors and different stages of chronic kidney disease (CKD). We studied 103 patients with CKD of different stages (1 to 5). PRF was measured by B-mode renal ultrasonography in the distal third between the cortex and the hepatic border and/or spleen. The PRF thickness was greater in CKD patients with impaired fasting glucose than in those with normal glucose levels (1.10 ± 0.40 cm vs. 0.85 ± 0.39 cm, P < 0.01). Patients in CKD stages 4 and 5 (glomerular filtration rate [GFR] < 30 mL/min/1.73 m2) had the highest PRF thickness. Serum triglyceride levels correlated positively with the PRF thickness; the PRF thickness was greater in patients with triglyceride levels ≥ 150 mg/dL (1.09 ± 0.40 cm vs. 0.86 ± 0.36 cm, P < 0.01). In patients with a GFR < 60 mL/min/1.73 m2, uric acid levels correlated positively with the PRF thickness (P < 0.05). In CKD patients, the PRF thickness correlated significantly with metabolic risk factors that could affect kidney function.eng
dc.identifier.issn22119132
dc.identifier.urihttps://hdl.handle.net/20.500.12442/3660
dc.language.isoengeng
dc.publisherThe Korean Society of Nephrologyeng
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.accessrightsinfo:eu-repo/semantics/closedAccessspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.source.urihttps://doi.org/10.23876/j.krcp.18.0155eng
dc.subjectCardiovasculareng
dc.subjectChronic kidney diseaseeng
dc.subjectDiabetesspa
dc.subjectMetabolic riskeng
dc.subjectPerirenal fateng
dc.subjectRenal insufficiencyeng
dc.titlePerirenal fat thickness is associated with metabolic risk factors in patients with chronic kidney diseaseeng
dc.typearticleeng
dcterms.referencesLevey AS, de Jong PE, Coresh J, et al. The definition, classification, and prognosis of chronic kidney disease: a KDIGO Controversies Conference report. Kidney Int 2011;80:17-28.eng
dcterms.referencesKDIGO CKD Work Group. Kidney Disease: Improving Global Outcomes (KDIGO) CKD Work Group. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney Int Suppl 2013;3:1-150.eng
dcterms.referencesTonelli M, Wiebe N, Culleton B, et al. Chronic kidney disease and mortality risk: a systematic review. J Am Soc Nephrol 2006;17:2034-2047.eng
dcterms.referencesGo AS, Chertow GM, Fan D, McCulloch CE, Hsu CY. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 2004;351:1296- 1305.eng
dcterms.referencesLeavey SF, McCullough K, Hecking E, Goodkin D, Port FK, Young EW. Body mass index and mortality in ‘healthier’ as compared with ‘sicker’ haemodialysis patients: results from the Dialysis Outcomes and Practice Patterns Study (DOPPS). Nephrol Dial Transplant 2001;16:2386-2394.eng
dcterms.referencesKalaitzidis RG, Siamopoulos KC. The role of obesity in kidney disease: recent findings and potential mechanisms. Int Urol Nephrol 2011;43:771-784.eng
dcterms.referencesHsu CY, McCulloch CE, Iribarren C, Darbinian J, Go AS. Body mass index and risk for end-stage renal disease. Ann Intern Med 2006;144:21-28.eng
dcterms.referencesWang Y, Chen X, Song Y, Caballero B, Cheskin LJ. Association between obesity and kidney disease: a systematic review and meta-analysis. Kidney Int 2008;73:19-33.eng
dcterms.referencesGarofalo C, Borrelli S, Minutolo R, Chiodini P, De Nicola L, Conte G. A systematic review and meta-analysis suggests obesity predicts onset of chronic kidney disease in the general population. Kidney Int 2017;91:1224-1235.eng
dcterms.referencesSpeliotes EK, Massaro JM, Hoffmann U, et al. Fatty liver is associated with dyslipidemia and dysglycemia independent of visceral fat: the Framingham Heart Study. Hepatology 2010;51:1979-1987.eng
dcterms.referencesMeshkani R, Adeli K. Hepatic insulin resistance, metabolic syndrome and cardiovascular disease. Clin Biochem 2009;42:1331-1346.eng
dcterms.referencesIacobellis G, Bianco AC. Epicardial adipose tissue: emerging physiological, pathophysiological and clinical features. Trends Endocrinol Metab 2011;22:450-457.eng
dcterms.referencesBettencourt N, Toschke AM, Leite D, et al. Epicardial adipose tissue is an independent predictor of coronary atherosclerotic burden. Int J Cardiol 2012;158:26-32.eng
dcterms.referencesD’Marco LG, Bellasi A, Kim S, Chen Z, Block GA, Raggi P. Epicardial adipose tissue predicts mortality in incident hemodialysis patients: a substudy of the Renagel in New Dialysis trial. Nephrol Dial Transplant 2013;28:2586-2595.eng
dcterms.referencesKarohl C, D’Marco L, Bellasi A, Raggi P. Hybrid myocardial imaging for risk stratification prior to kidney transplantation: added value of coronary calcium and epicardial adipose tissue. J Nucl Cardiol 2013;20:1013-1020.eng
dcterms.referencesRea DJ, Heimbach JK, Grande JP, et al. Glomerular volume and renal histology in obese and non-obese living kidney donors. Kidney Int 2006;70:1636-1641.eng
dcterms.referencesChughtai HL, Morgan TM, Rocco M, et al. Renal sinus fat and poor blood pressure control in middle-aged and elderly individuals at risk for cardiovascular events. Hypertension 2010;56:901-906.eng
dcterms.referencesMontani JP, Carroll JF, Dwyer TM, Antic V, Yang Z, Dulloo AG. Ectopic fat storage in heart, blood vessels and kidneys in the pathogenesis of cardiovascular diseases. Int J Obes Relat Metab Disord 2004;28 Suppl 4:S58-S65.eng
dcterms.referencesVogt FM, Ruehm S, Hunold P, et al. [Rapid total body fat measurement by magnetic resonance imaging: quantification and topography]. Rofo 2007;179:480-486. German.eng
dcterms.referencesTokunaga K, Matsuzawa Y, Ishikawa K, Tarui S. A novel technique for the determination of body fat by computed tomography. Int J Obes 1983;7:437-445.eng
dcterms.referencesStallone DD, Stunkard AJ, Wadden TA, Foster GD, Boorstein J, Arger P. Weight loss and body fat distribution: a feasibility study using computed tomography. Int J Obes 1991;15:775- 780.eng
dcterms.referencesArmellini F, Zamboni M, Rigo L, et al. The contribution of sonography to the measurement of intra-abdominal fat. J Clin Ultrasound 1990;18:563-567.eng
dcterms.referencesKawasaki S, Aoki K, Hasegawa O, et al. Sonographic evaluation of visceral fat by measuring para- and perirenal fat. J Clin Ultrasound 2008;36:129-133.eng
dcterms.referencesSun X, Han F, Miao W, Hou N, Cao Z, Zhang G. Sonographic evaluation of para- and perirenal fat thickness is an independent predictor of early kidney damage in obese patients. Int Urol Nephrol 2013;45:1589-1595.eng
dcterms.referencesLamacchia O, Nicastro V, Camarchio D, et al. Para- and perirenal fat thickness is an independent predictor of chronic kidney disease, increased renal resistance index and hyperuricaemia in type-2 diabetic patients. Nephrol Dial Transplant 2011;26:892-898.eng
dcterms.referencesWeisinger JR, Kempson RL, Eldridge FL, Swenson RS. The nephrotic syndrome: a complication of massive obesity. Ann Intern Med 1974;81:440-447.eng
dcterms.referencesSchiffrin EL, Lipman ML, Mann JF. Chronic kidney disease: effects on the cardiovascular system. Circulation 2007;116:85-97.eng
dcterms.referencesde Boer IH, Sibley SD, Kestenbaum B, et al; Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study Research Group. Central obesity, incident microalbuminuria, and change in creatinine clearance in the epidemiology of diabetes interventions and complications study. J Am Soc Nephrol 2007;18:235-243.eng
dcterms.referencesValensi P, Assayag M, Busby M, Pariès J, Lormeau B, Attali JR. Microalbuminuria in obese patients with or without hypertension. Int J Obes Relat Metab Disord 1996;20:574-579.eng
dcterms.referencesKim H, Kim HJ, Shin N, et al. Visceral obesity is associated with microalbuminuria in nondiabetic Asians. Hypertens Res 2014;37:679-684.eng
dcterms.referencesDrüeke TB, Massy ZA. Atherosclerosis in CKD: differences from the general population. Nat Rev Nephrol 2010;6:723- 735.eng
dcterms.referencesRitz E, Wanner C. Lipid abnormalities and cardiovascular risk in renal disease. J Am Soc Nephrol 2008;19:1065-1070.eng
dcterms.referencesScarpioni R, Ricardi M, Melfa L, Cristinelli L. Dyslipidemia in chronic kidney disease: are statins still indicated in reduction cardiovascular risk in patients on dialysis treatment? Cardiovasc Ther 2010;28:361-368.eng
dcterms.referencesWanner C, Krane V. Uremia-specific alterations in lipid metabolism. Blood Purif 2002;20:451-453.eng
dcterms.referencesAdánez G, Castells MT, García Pérez B, et al. Effects of atorvastatin on progression-regression of renal injury in hyperlipidemic chickens. Histol Histopathol 2008;23:1131-1142.eng
dcterms.referencesFeig DI, Kang DH, Johnson RJ. Uric acid and cardiovascular risk. N Engl J Med 2008;359:1811-1821.eng
dcterms.referencesKivity S, Kopel E, Maor E, et al. Association of serum uric acid and cardiovascular disease in healthy adults. Am J Cardiol 2013;111:1146-1151.eng
dcterms.referencesLv Q, Meng XF, He FF, et al. High serum uric acid and increased risk of type 2 diabetes: a systemic review and meta-analysis of prospective cohort studies. PLoS One 2013;8:e56864.eng
dcterms.referencesObermayr RP, Temml C, Gutjahr G, Knechtelsdorfer M, Oberbauer R, Klauser-Braun R. Elevated uric acid increases the risk for kidney disease. J Am Soc Nephrol 2008;19:2407- 2413.eng
dcterms.referencesZoccali C, Maio R, Mallamaci F, Sesti G, Perticone F. Uric acid and endothelial dysfunction in essential hypertension. J Am Soc Nephrol 2006;17:1466-1471.eng

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