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Perirenal fat thickness is associated with metabolic risk factors in patients with chronic kidney disease

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dc.contributor.authorD´Marco, Luisspa
dc.contributor.authorSalazar, Juanspa
dc.contributor.authorCortez, Mariespa
dc.contributor.authorSalazar, Maríaspa
dc.contributor.authorWettel, Marjorieeng
dc.contributor.authorLima-Martínez, Marcosspa
dc.contributor.authorRojas, Edwardspa
dc.contributor.authorRoque, Willyspa
dc.contributor.authorBermúdez, Valmorespa
dc.date.accessioned2019-08-08T15:03:04Z
dc.date.available2019-08-08T15:03:04Z
dc.date.issued2019
dc.description.abstractAdipose tissue accumulation in specific body compartments has been associated with diabetes, hypertension and dyslipidemia. Perirenal fat (PRF) may lead to have direct lipotoxic effects on renal function and intrarenal hydrostatic pressure. This study was undertaken to explore the association of PRF with cardiovascular risk factors and different stages of chronic kidney disease (CKD). We studied 103 patients with CKD of different stages (1 to 5). PRF was measured by B-mode renal ultrasonography in the distal third between the cortex and the hepatic border and/or spleen. The PRF thickness was greater in CKD patients with impaired fasting glucose than in those with normal glucose levels (1.10 ± 0.40 cm vs. 0.85 ± 0.39 cm, P < 0.01). Patients in CKD stages 4 and 5 (glomerular filtration rate [GFR] < 30 mL/min/1.73 m2) had the highest PRF thickness. Serum triglyceride levels correlated positively with the PRF thickness; the PRF thickness was greater in patients with triglyceride levels ≥ 150 mg/dL (1.09 ± 0.40 cm vs. 0.86 ± 0.36 cm, P < 0.01). In patients with a GFR < 60 mL/min/1.73 m2, uric acid levels correlated positively with the PRF thickness (P < 0.05). In CKD patients, the PRF thickness correlated significantly with metabolic risk factors that could affect kidney function.eng
dc.identifier.issn22119132
dc.identifier.urihttps://hdl.handle.net/20.500.12442/3660
dc.language.isoengeng
dc.publisherThe Korean Society of Nephrologyeng
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacionaleng
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacionaleng
dc.rights.accessrightsinfo:eu-repo/semantics/closedAccessspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.source.urihttps://doi.org/10.23876/j.krcp.18.0155eng
dc.subjectCardiovasculareng
dc.subjectChronic kidney diseaseeng
dc.subjectDiabetesspa
dc.subjectMetabolic riskeng
dc.subjectPerirenal fateng
dc.subjectRenal insufficiencyeng
dc.titlePerirenal fat thickness is associated with metabolic risk factors in patients with chronic kidney diseaseeng
dc.typearticleeng
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