Reset osmostat
| datacite.rights | http://purl.org/coar/access_right/c_abf2 | |
| dc.contributor.author | Avallay, Flavia Paola | |
| dc.contributor.author | Musso Enz, Victoria Paula | |
| dc.contributor.author | Aroca-Martinez, Gustavo | |
| dc.contributor.author | Musso, Carlos | |
| dc.date.accessioned | 2025-06-09T22:22:25Z | |
| dc.date.available | 2025-06-09T22:22:25Z | |
| dc.date.issued | 2025 | |
| dc.description.abstract | Introduction: Reset osmostat (RO) is a common syndrome, making up about 30 % of patients with hyponatremia. Objective: Conduct a comprehensive review of osmostat reset, describing its clinical, pathophy siologic, diagnostic, and therapeutic aspects. Methodology: A narrative review was conducted based on the main articles published in the medical literature. Results: Reset osmostat has a low plasma osmolality threshold, which consequently leads to an elevation in antidiuretic hormone at a lower plasma osmolarity, along with normal water load excretion and intact urine diluting ability, while maintaining normal sodium balance. Reset osmostat can be observed in pregnancy, older age, quadriplegia, psychosis, cerebral hemorrhage, encephalitis, dementia, alcoholism, malnutrition, malignancy, and particular infectious diseases. Conclusions: Reset osmostat often resets to normal if it is the consequence of a reversible cli nical setting; however, this normalization might not happen if it is secondary to an irreversible condition. In such cases, treatment is required similar to that of any hyponatremia in order to avoid its negative consequences. | eng |
| dc.description.abstract | Introducción: el reset del osmostato (RO) es un síndrome común que representa aproximadamente el 30 % de los pacientes con hiponatremia. Objetivo: realizar una revisión exhaustiva sobre el reset del osmostato, describiendo sus aspectos clínicos, fisiopatológicos, diagnósticos y terapéuticos. Metodología: se realizó una revisión narrativa basada en los principales artículos publicados en la literatura médica. Resultados: el reset del osmostato tiene un umbral de osmolalidad plasmática bajo que, en consecuen cia, conduce a una elevación de la hormona antidiurética y a una osmolaridad plasmática más baja, junto con una capacidad intacta para diluir la orina y mantener el equilibrio normal de sodio. El reset del osmostato se puede observar en el embarazo, la vejez, la cuadriplejía, la psicosis, la hemorragia cerebral, la encefalitis, la demencia, el alcoholismo, la desnutrición, las enfermedades malignas y en determinadas enfermedades infecciosas. Conclusión: el reset del osmostato a menudo se restablece a la normalidad si ha sido inducido por una enfermedad reversible; sin embargo, puede no normalizarse si lo induce una condición irreversible. En tales casos, se requiere un tratamiento similar al de cualquier hiponatremia para evitar sus consecuencias negativas. | spa |
| dc.format.mimetype | ||
| dc.identifier.citation | Avallay FP, Musso-Enz VP, Aroca-Martinez G, Musso CG. Reset osmostat. Rev.Colomb. Nefrol. 2025;12(2), e784. https://doi.org/10.22265/acnef.12.2.784 | |
| dc.identifier.doi | http://doi.org/10.22265/acnef.12.2.784 | |
| dc.identifier.issn | 25005006 (Electrónico) | |
| dc.identifier.issn | 23897708 (Impreso) | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12442/16658 | |
| dc.identifier.url | https://revistanefrologia.org/index.php/rcn/article/view/784 | |
| dc.language.iso | eng | |
| dc.publisher | Asociación Colombiana de Nefrología e Hipertensión Arterial | spa |
| dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | eng |
| dc.rights.accessrights | info:eu-repo/semantics/openAccess | |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.source | Revista Colombiana de Nefrología | spa |
| dc.source | Rev. Colomb. Nefrol. | eng |
| dc.source | Vol. 12 No. 2, (2025) | spa |
| dc.subject | Hiponatremia | spa |
| dc.subject | Reset del osmostato | spa |
| dc.subject | Diagnóstico | spa |
| dc.subject | Concentración osmolar | spa |
| dc.subject | Vasopresinas | spa |
| dc.subject | Enfermedades transmisibles | spa |
| dc.subject.keywords | Hyponatremia | eng |
| dc.subject.keywords | Reset osmostat | eng |
| dc.subject.keywords | Diagnosis | eng |
| dc.subject.keywords | Osmolar concentration | eng |
| dc.subject.keywords | Vasopressins | eng |
| dc.subject.keywords | Communicable diseases | eng |
| dc.title | Reset osmostat | eng |
| dc.type.driver | info:eu-repo/semantics/article | |
| dc.type.spa | Artículo científico | |
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| oaire.version | info:eu-repo/semantics/publishedVersion |