Desenlaces clínicos en pacientes con lesión cerebral aguda no traumática y variación del diámetro de la vaina del nervio óptico en una unidad de cuidado intensivo de Barranquilla desde diciembre del año 2023 hasta diciembre del 2024
| datacite.rights | http://purl.org/coar/access_right/c_16ec | |
| dc.contributor.advisor | Rebolledo Maldonado, Carlos | |
| dc.contributor.author | González González, Ivonne del Carmen | |
| dc.contributor.author | Forero Palacio, Víctor Alfonso | |
| dc.date.accessioned | 2025-07-09T13:30:11Z | |
| dc.date.available | 2025-07-09T13:30:11Z | |
| dc.date.issued | 2025 | |
| dc.description.abstract | Introducción: Las lesiones cerebrales agudas no traumáticas (LCA-NT) constituyen una causa frecuente de ingreso a UCI. El monitoreo no invasivo del estado neurológico mediante el diámetro de la vaina del nervio óptico (DVNO) se ha propuesto como una herramienta útil para detectar hipertensión endocraneana. Objetivo: Evaluar la asociación entre el DVNO y los desenlaces clínicos en pacientes con LCA-NT en una UCI de cuarto nivel en Barranquilla. Métodos: Estudio prospectivo, descriptivo y de cohorte longitudinal. Se incluyeron pacientes adultos con diagnóstico confirmado de LCA-NT entre diciembre de 2023 y diciembre del 2024. Se realizaron mediciones seriadas del DVNO a las 24, 48 y 72 horas. Se evaluaron la mortalidad intrahospitalaria, la necesidad de ventilación mecánica invasiva (VMI), la duración de estancia hospitalaria y estancia en UCI. Se aplicaron pruebas univariadas y regresión logística multivariada. Resultados: Se analizaron 82 pacientes. Un DVNO ≥ 5 mm a las 24 horas se asoció significativamente con mayor mortalidad intrahospitalaria ((OR = 2.56; p = 0.008; IC 95%: 1.28–5.12), necesidad de VMI (OR = 2.30; p = 0.012; IC 95%: 1.20–4.40). La estancia hospitalaria y en UCI fue significativamente más prolongada en los pacientes que presentaron desenlace fatal. Conclusiones: El DVNO es un biomarcador accesible, no invasivo y de utilidad pronóstica en pacientes con LCA-NT. Su inclusión en los algoritmos clínicos permite anticipar complicaciones graves, especialmente en contextos sin monitoreo invasivo de la PIC. | spa |
| dc.description.abstract | Introduction: Non-traumatic acute brain injury (NT-ABI) is a frequent and complex condition in intensive care units. Non-invasive neurological monitoring using optic nerve sheath diameter (ONSD) has emerged as a promising surrogate for estimating intracranial pressure (ICP). Objective: To evaluate the association between ONSD and clinical outcomes in NT-ABI patients admitted to a fourth-level ICU in Barranquilla, Colombia. Methods: Prospective, descriptive, longitudinal study. Adult patients diagnosed with NT-ABI between December 2023 and December 2024 were included. Serial ONSD measurements were taken at 24, 48, and 72 hours. Outcomes included in-hospital mortality, need for invasive mechanical ventilation (IMV), hospital stay and ICU length of stay. Univariate analysis and multivariate logistic regression were applied. Results: A total of 82 patients were analyzed. An ONSD ≥ 5 mm at 24 hours was significantly associated with higher in-hospital mortality (adjusted OR: 2.56; p = 0.008; IC 95%: 1.28–5.12), increased need for IMV (adjusted OR: 2.30; p = 0.012; IC 95%: 1.20–4.40). Patients who died had significantly longer hospital and ICU stays. Conclusions: ONSD is a reliable, non-invasive prognostic biomarker in NT-ABI. Its integration into critical care protocols may improve early decision-making and reduce complications from unrecognized intracranial hypertension. | eng |
| dc.format.mimetype | ||
| dc.identifier.uri | https://hdl.handle.net/20.500.12442/16812 | |
| dc.language.iso | spa | |
| dc.publisher | Ediciones Universidad Simón Bolívar | spa |
| dc.publisher | Facultad de Ciencias de la Salud | spa |
| dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | eng |
| dc.rights.accessrights | info:eu-repo/semantics/restrictedAccess | |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.subject | Lesión cerebral aguda | spa |
| dc.subject | Diámetro de la vaina del nervio óptico | spa |
| dc.subject | Ultrasonografía | spa |
| dc.subject | Presión intracraneana | spa |
| dc.subject | Cuidados intensivos | spa |
| dc.subject | Monitoreo no invasivo | spa |
| dc.subject.keywords | Acute brain injury | eng |
| dc.subject.keywords | Optic nerve sheath diameter | eng |
| dc.subject.keywords | Ultrasonography | eng |
| dc.subject.keywords | Intracranial pressure | eng |
| dc.subject.keywords | Intensive care | eng |
| dc.subject.keywords | Non-invasive monitoring | eng |
| dc.title | Desenlaces clínicos en pacientes con lesión cerebral aguda no traumática y variación del diámetro de la vaina del nervio óptico en una unidad de cuidado intensivo de Barranquilla desde diciembre del año 2023 hasta diciembre del 2024 | spa |
| dc.type.driver | info:eu-repo/semantics/other | |
| dc.type.spa | Otros | |
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| oaire.version | info:eu-repo/semantics/acceptedVersion | |
| sb.programa | Especialización en Medicina Crítica y Cuidados Intensivos | spa |
| sb.sede | Sede Barranquilla | spa |
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