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La velocidad de onda de pulso y el envejecimiento arterial en sujetos con y sin diabetes mellitus tipo 2

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dc.contributor.authorBuelvas-Herazo, Jannes
dc.contributor.authorUrina-Triana, Miguel
dc.contributor.authorMantilla- Morrón, Mirary
dc.contributor.authorUrina-Jassir, Daniela
dc.contributor.authorGaleano-Muñoz, Luisa
dc.contributor.authorUrina-Triana, Manuel
dc.contributor.authorQuintero-Baiz, Adalberto
dc.date.accessioned2019-01-16T14:04:53Z
dc.date.available2019-01-16T14:04:53Z
dc.date.issued2018
dc.description.abstractIntroducción y Objetivos: La velocidad de onda de pulso (VOP) es un procedimiento para evaluar la rigidez arterial con utilidad pronostica cardiovascular. En este estudio comparamos la VOP entre sujetos con y sin Diabetes Mellitus tipo 2 (DM2) para conocer sus diferencias y cuáles son los factores que las ocasionan. Métodos y Materiales: Estudio de cohorte en 39 sujetos (12 con DM2 y 27 sin DM2). Después de reposo de 15 minutos, se midió en la arteria braquial en forma oscilométrica la VOP mediante dispositivo Mobil-O-Graph, y con dos tomas consecutivas se obtuvo el promedio. El valor obtenido se comparó contra los valores normales esperados de referencia de acuerdo con la edad. Se calculó la edad arterial aproximada. Se utilizó SPSS para Mac versión 24 para hacer los análisis y se consideró significancia estadística a una p<0.05. Resultados: Los sujetos con DM2 tuvieron mayor VOP que los sujetos sin DM2 (p=0.02); a mayor tiempo de evolución de la DM2 mayor fue la VOP (p=0.01). La correlación bivariada bilateral (correlación de Pearson) entre edad cronológica y edad arterial aproximada calculada por el Mobil-O-Graph fue 0,957 (p=0.00) y entre la VOP y la edad cronológica fue de 0,914 (p=0,000). Conclusiones: La VOP aumentada está relacionada con el tiempo de evolución de la DM2 y existió correlación positiva con la edad cronológica. Más estudios se necesitan para definir valores de referencia y de normalidad del VOP y debería ser una herramienta de evaluación cardiovascular en el sujeto con DM2.spa
dc.description.abstractIntroduction and Objectives: Pulse wave velocity (PWV) is a measure of arterial stiffness which has been used to determine cardiovascular prognosis. In this study, we compared PWV between patients with and without Diabetes Mellitus type 2 (DM2) in order to identify their differences and associated factors. Methods and Materials: This was a cohort study where 39 subjects were enrolled (12 with DM2 and 27 without DM2). PWV was measured in the brachial artery through oscillometry using a Mobil-O-Graph device after 15 minutes of rest. An average value was obtained from two consecutive measurements. We compared this measurement with the normal expected values of reference according to patient’s age. The approximate arterial age was also calculated. SPSS for Mac version 24 was used to make the analyzes and statistical significance was considered a p value <0.05. Results: Subjects with DM2 had higher PWV than subjects without DM2 (p = 0.02). Additionally, the longer time with DM2 a higher PWV was seen (p = 0.01). Bilateral bivariate correlation (Pearson correlation) between chronological age and approximate arterial age was 0.957 (p = 0.00) whereas between PWV and chronological age was 0.914 (p = 0.000). Conclusions: We concluded that higher levels of PWV are correlated to the time of evolution of DM2. PWV has also a positive correlation with chronological age. More studies with bigger populations are yet needed to determine reference and normal values of PWV, as it may be used as a tool for cardiovascular assessment in patients with DM2.eng
dc.identifier.issn18564550
dc.identifier.urihttp://hdl.handle.net/20.500.12442/2445
dc.language.isospaspa
dc.publisherCooperativa servicios y suministros 212518 RSspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.sourceRevista Latinoamericana de Hipertensiónspa
dc.sourceVol. 13, No. 4 (2018)spa
dc.source.urihttp://www.revhipertension.com/rlh_4_2018/14_velocidad_onda_pulso.pdfspa
dc.subjectRigidez vascularspa
dc.subjectDiabetes Mellitusspa
dc.subjectVelocidad de onda de pulsospa
dc.subjectVascular rigidityeng
dc.subjectDiabetes Mellituseng
dc.subjectPulse wave velocityeng
dc.titleLa velocidad de onda de pulso y el envejecimiento arterial en sujetos con y sin diabetes mellitus tipo 2spa
dc.title.alternativePulse wave velocity and arterial aging in subjects with and without type 2 diabetes mellituseng
dc.typearticlespa
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