DNA damage, salivary cortisol levels, and cognitive parameters in a nursing team

dc.contributor.authorBortolotto, Iranez
dc.contributor.authorScherer de Brum, Ana Paula
dc.contributor.authorNikolova Guecheva, Temenouga
dc.contributor.authorMilano de Souza, Larissa
dc.contributor.authorLia de Paula-Ramos, Ana Ligia
dc.contributor.authorTrindade, Cristiano
dc.contributor.authorRosat Consiglio, Angelica
dc.description.abstractIn a cross-sectional study of women in a nursing team at a university hospital in southern Brazil, we studied DNA damage, salivary cortisol levels, and cognition. DNA damage was measured in blood leukocytes with the comet assay and the micronucleus test. Salivary cortisol levels were determined upon waking, 30 min later, and at bedtime. Cognition was evaluated according to the Stroop, Digit span and Word span tests. Cortisol levels on waking up were associated negatively with the number of years the employee worked at the institution and positively with the DNA damage in comet assay. Cognitive scores were lower when the cortisol levels were low at awakening and high at bedtime; and were associated positively with educational level. Cortisol status may influence overall health as well as essential work skills, such as attention.eng
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.sourceMutation Research/Genetic Toxicology and Environmental Mutagenesiseng
dc.sourceVol. 861-862 (2021)
dc.subjectComet assayeng
dc.subjectMicronucleus testeng
dc.subjectOccupational healtheng
dc.titleDNA damage, salivary cortisol levels, and cognitive parameters in a nursing teameng
dc.type.spaArtículo científicospa
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