Characterization of patients with diabetic kidney disease nonalbuminuric phenotype. A single-center observational study

Introduction: The phenotypes with albuminuria and the nonalbuminuric phenotype in diabetic kidney disease (DKD) are known. The nonalbuminuric phenotype is defined with an estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m2 associated with km il.;p.albuminuria- creatinuria ratio (ACR) less than 30 mg/gr. The objective of the present study was to describe the clinical characteristics of patients with DKD nonalbuminuric phenotype (nADKD). Methods: This is an observational, descriptive study of patients treated at an IPS in Cartagena, Colombia, from 2021 to 2022. Results: Of a total of 7698 patients with DKD criteria, 1714 patients (22.3%) had nA-DKD criteria, with a median age of 69 years (IQR 62-76), and women (75.73%). A total of 85% had hypertension, (22.3%) dyslipidemia, and the average BMI was in the overweight range. 9.5% had a history of smoking. Little presence of diabetic retinopathy was found. Conclusion: Nonalbuminuric phenotype diabetic kidney disease is not uncommon in our environment. In general, the characteristics of our patients are very similar to those reported in other series.

Citación

Salas Carmona YH, Serpa Diaz D, Salas Carmona YC, Ramos Clason E, Raad Sarabia M, Daza Arnedo R, Cardona Blanco M, Parra Sánchez P, Rico Fontalvo J. Characterization of patients with diabetic kidney disease nonalbuminuric phenotype. A single-center observational study. REV SEN 2024;12(2):121-130.