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Importance of high triglycerides levels between novel coronary risk factors

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dc.contributor.authorBermúdez, Valmore
dc.contributor.authorSalazar, Juan
dc.contributor.authorCalvo, María
dc.contributor.authorMartínez, María
dc.contributor.authorAñez, Roberto
dc.contributor.authorRivas-Ríos, José
dc.contributor.authorChacín, Maricarmen
dc.contributor.authorHernández, Juan
dc.contributor.authorGraterol, Modesto
dc.contributor.authorRojas, Joselyn
dc.date.accessioned2018-03-13T15:33:45Z
dc.date.available2018-03-13T15:33:45Z
dc.date.issued2017-11
dc.description.abstractIntroduction: The analysis of new cardiovascular risk factors is under an extensive debate in the cardiology and metabolic research fields. Objective: To determine the main factors that contribute to the classification of individuals with higher coronary risk in the adult population from Maracaibo, Venezuela. Methods: A descriptive, cross-sectional study with multistage random sampling in 1379 individuals belonging to the Maracaibo City Metabolic Syndrome Prevalence Study (MMSPS) was performed. They were classified according to the coronary risk by Framingham-Wilson equation adapted to our population. The association between various risk factors was evaluated by ordinal logistic regression models. Results: 1,379 subjects (females 55.9%; n = 771) were evaluated, 66.2% (n = 913) were classified with low coronary risk. In univariate ( 2 = 112.35; p < 0.00001) and multivariate analysis [OR: 3.98 (2.39-6.63); p < 0.01], the main factors associated to be classified as the highest risk category were hypertriglyceridemia. Conclusion: There are several factors that should be included in predictive models use worldwide. The most important in our population were dyslipidemia such as hypertriglyceridemia, hyperlipoproteinemia (a) and insulin resistance.eng
dc.description.abstractIntroducción: El análisis de nuevos factores de riesgo cardiovascular constituye un tema de amplio debate en la investigación cardio-metabólica. Objetivo: Determinar los principales factores que contribuyen a la clasificación de sujetos en las categorías de mayor riesgo coronario en individuos adultos de la ciudad de Maracaibo, Venezuela. Métodos: Estudio descriptivo, trasversal con muestreo aleatorio multietapas en 1.379 individuos pertenecientes al Estudio de Prevalencia de Síndrome Metabólico de la Ciudad de Maracaibo (EPSMM). Estos fueron clasificaron de acuerdo con el riesgo coronario mediante la fórmula Framingham-Wilson adaptada para nuestra población. Se evaluó la asociación entre diversos factores de riesgo mediante un modelo de regresión logística ordinal. Resultados: Se evaluaron 1.379 sujetos (mujeres: 55,9%; n = 771), de los cuales un 66,2% (n = 913) fueron clasificados en riesgo coronario bajo. Tanto en el contexto univariante ( 2 = 112,35; p < 0,00001) como multivariante [OR: 3,98 (2,39-6,63); p < 0,01] el principal factor asociado para ser clasificado en las categorías de riesgo más elevado fue la hipertrigliceridemia. Conclusión: Existen numerosos factores que deberían ser incluidos en los modelos de predicción empleados en el mundo, en cuyo caso las dislipidemias: hipertrigliceridemia, hiperlipoproteinemia (a), e insulinorresistencia son las más importantes en nuestra población.spa
dc.identifier.issn23573260
dc.identifier.urihttp://hdl.handle.net/20.500.12442/1861
dc.language.isoengspa
dc.publisherSociedad Colombiana de Cardiología y Cirugía Cardiovascular.spa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.licenseLicencia de Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacionalspa
dc.sourceRevista Colombiana de Cardiologíaspa
dc.sourceVol. 24, No.6 (2017)spa
dc.source.urihttp://www.elsevier.es/es-revista-revista-colombiana-cardiologia-203-articulo-importance-high-triglycerides-levels-between-S0120563317300396
dc.subjectLipidseng
dc.subjectInsulineng
dc.subjectRisk factorseng
dc.subjectPreventioneng
dc.subjectLípidosspa
dc.subjectInsulinaspa
dc.subjectFactores de riesgospa
dc.subjectPrevenciónspa
dc.titleImportance of high triglycerides levels between novel coronary risk factorseng
dc.title.alternativeImportancia de niveles elevados de triglicéridos entre los factores de riesgo coronario nuevosspa
dc.typearticlespa
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