Computational assessment of stomach tumor volume from multi-slice computerized tomography images in presence of type 2 cancer [version 2; referees: 1 approved, 1 not approved]

dc.contributor.authorChacón, Gerardo
dc.contributor.authorRodríguez, Johel E.
dc.contributor.authorBermúdez, Valmore
dc.contributor.authorVera, Miguel
dc.contributor.authorHernández, Juan Diego
dc.contributor.authorVargas, Sandra
dc.contributor.authorPardo, Aldo
dc.contributor.authorLameda, Carlos
dc.contributor.authorMadriz, Delia
dc.contributor.authorBravo, Antonio J.
dc.date.accessioned2018-11-13T22:04:48Z
dc.date.available2018-11-13T22:04:48Z
dc.date.issued2018-07
dc.description.abstractBackground: The multi–slice computerized tomography (MSCT) is a medical imaging modality that has been used to determine the size and location of the stomach cancer. Additionally, MSCT is considered the best modality for the staging of gastric cancer. One way to assess the type 2 cancer of stomach is by detecting the pathological structure with an image segmentation approach. The tumor segmentation of MSCT gastric cancer images enables the diagnosis of the disease condition, for a given patient, without using an invasive method as surgical intervention. Methods: This approach consists of three stages. The initial stage, an image enhancement, consists of a method for correcting non homogeneities present in the background of MSCT images. Then, a segmentation stage using a clustering method allows to obtain the adenocarcinoma morphology. In the third stage, the pathology region is reconstructed and then visualized with a three–dimensional (3–D) computer graphics procedure based on marching cubes algorithm. In order to validate the segmentations, the Dice score is used as a metric function useful for comparing the segmentations obtained using the proposed method with respect to ground truth volumes traced by a clinician. Results: A total of 8 datasets available for patients diagnosed, from the cancer data collection of the project, Cancer Genome Atlas Stomach Adenocarcinoma (TCGASTAD) is considered in this research. The volume of the type 2 stomach tumor is estimated from the 3–D shape computationally segmented from the each dataset. These 3–D shapes are computationally reconstructed and then used to assess the morphopathology macroscopic features of this cancer. Conclusions: The segmentations obtained are useful for assessing qualitatively and quantitatively the stomach type 2 cancer. In addition, this type of segmentation allows the development of computational models that allow the planning of virtual surgical processes related to type 2 cancer.eng
dc.identifier.issn20461402
dc.identifier.urihttp://hdl.handle.net/20.500.12442/2350
dc.language.isoengeng
dc.publisherF1000 Research Ltda.eng
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.rights.licenseLicencia de Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacionalspa
dc.sourceF1000 Researcheng
dc.sourceVol. 7, No.1098 (2018)spa
dc.source.urihttps://f1000researchdata.s3.amazonaws.com/manuscripts/18013/b79a3338-adf4-4ee7-bdb2-6cde1e2e3ced_14491_-_gerardo_chacon_v2.pdf?doi=10.12688/f1000research.14491.2&numberOfBrowsableCollections=14&numberOfBrowsableGateways=22eng
dc.subjectStomach tumoreng
dc.subjectType 2 cancereng
dc.subjectMedical imagingeng
dc.subjectMulti–slice computerized tomographyeng
dc.subjectImage enhancementeng
dc.subjectRegion growing methodeng
dc.subjectMarching cubeseng
dc.subjectThree-dimensional reconstructioneng
dc.titleComputational assessment of stomach tumor volume from multi-slice computerized tomography images in presence of type 2 cancer [version 2; referees: 1 approved, 1 not approved]eng
dc.typearticleeng
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