Síntesis y caracterización de una nueva metaloporfirina de Co3+ derivada de la 5,10 15,20-tetrakis-(4-etilfenil)porfirina.

Gómez Galindo, Gisell Marlens; Acuña Cabarcas, Kelly Jhoana; Pernett De La Rosa, Santiago

Síntesis y caracterización de una nueva metaloporfirina de Co3+ derivada de la 5,10 15,20-tetrakis-(4-etilfenil)porfirina.

datacite.rights	http://purl.org/coar/access_right/c_f1cf
dc.contributor.advisor	Espitia Almeida, Fabián Andrés
dc.contributor.advisor	Barragán Avilez, Clara Milena
dc.contributor.advisor	Navarro Gómez, Sirlhey Janety
dc.contributor.author	Gómez Galindo, Gisell Marlens
dc.contributor.author	Acuña Cabarcas, Kelly Jhoana
dc.contributor.author	Pernett De La Rosa, Santiago
dc.date.accessioned	2025-06-16T21:31:46Z
dc.date.available	2025-06-16T21:31:46Z
dc.date.issued	2025
dc.description.abstract	Las porfirinas y metaloporfirinas tienen amplias aplicaciones debido a su versatilidad. En la naturaleza, participan en el transporte de oxígeno (hemoglobina y mioglobina), la fotosíntesis (clorofila) y la catálisis enzimática (citocromo P450). En tecnología y medicina, se usan en la terapia fotodinámica antimicrobiana, conversión de energía y en catálisis. Su capacidad para coordinar metales y generar reacciones específicas las hace esenciales en procesos biológicos y aplicaciones avanzadas. Objetivo. Sintetizar y caracterizar una nueva metaloporfirina de cobalto Co3+ derivada de la 5, 10, 15, 20-tetrakis(4- etilfenil)porfirina.	spa
dc.description.abstract	Porphyrins and metalloporphyrins have wide-ranging applications due to their versatility. In nature, they participate in oxygen transport (hemoglobin and myoglobin), photosynthesis (chlorophyll), and enzymatic catalysis (cytochrome P450). In technology and medicine, they are used in antimicrobial photodynamic therapy, energy conversion, and catalysis. Their ability to coordinate metals and promote specific reactions makes them essential in biological processes and advanced applications. Objective. To synthesize and characterize a new cobalt (III) metalloporphyrin derived from 5,10,15,20-tetrakis(4- ethylphenyl) porphyrin.	eng
dc.format.mimetype	pdf
dc.identifier.uri	https://hdl.handle.net/20.500.12442/16683
dc.language.iso	spa
dc.publisher	Ediciones Universidad Simón Bolívar	spa
dc.publisher	Facultad de Ciencias Básicas y Biomédicas	spa
dc.rights	Attribution-NonCommercial-NoDerivatives 4.0 International	eng
dc.rights.accessrights	info:eu-repo/semantics/embargoedAccess
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject	Metaloporfirina	spa
dc.subject	Porfirina	spa
dc.subject	Cobalto	spa
dc.subject	Síntesis	spa
dc.subject	Caracterización	spa
dc.subject	UVVis	spa
dc.subject	FTIR-ATR	spa
dc.subject.keywords	Metalloporphyrin	eng
dc.subject.keywords	Porphyrin	eng
dc.subject.keywords	Cobalt	eng
dc.subject.keywords	Synthesis	eng
dc.subject.keywords	Characterization	eng
dc.subject.keywords	UV-Vis	eng
dc.subject.keywords	FTIR-ATR	eng
dc.title	Síntesis y caracterización de una nueva metaloporfirina de Co3+ derivada de la 5,10 15,20-tetrakis-(4-etilfenil)porfirina.	spa
dc.type.driver	info:eu-repo/semantics/other
dc.type.spa	Trabajo de grado - pregrado
dcterms.references	Abada, Z., Ferrié, L., Akagah, B., Lormier, A. T., & Figadère, B. (2012). Synthesis and characterization of original N-meso chiral substituted diarylporphyrins. Tetrahedron Letters. 53(51), 6961. https://doi.org/10.1016/j.tetlet.2012.10.041	eng
dcterms.references	Arredondo Espinoza, E. U. (2014). Síntesis de porfirinas y metaloporfirinas no simétricas funcionalizadas con L-glutamato y evaluación de sus propiedades fotodinámicas y anticancerígenas (Tesis doctoral, Universidad Autónoma de Nuevo León).	spa
dcterms.references	Baran, E. J. (2018). Cobalto: un elemento crítico y estratégico. Anales de la Academia Nacional de Ciencias Exactas, Físicas y Naturales, 70, 77–106. https://doi.org/10.31404/anales.70.77	spa
dcterms.references	Bilanin Artigado, C. (2020). Metaloporfirinas: Síntesis, actividad catalítica y soporte en materiales 2D [Tesis de maestría o doctoral, institución no especificada].	spa
dcterms.references	Espitia-Almeida, F., Díaz-Uribe, C., Vallejo, W., Gómez-Camargo, D., Bohórquez, A. R. R., Zarate, X., & Schott, E. (2022). Photophysical characterization and in vitro antileishmanial effect of 5,10,15,20-tetrakis(4-fluorophenyl) porphyrin and the metal (Zn(II), Sn(IV), Mn(III), and V(IV)) derivatives. Biometals, 35, 503–515. https://doi.org/10.1007/s10534-022-00384-z	eng
dcterms.references	Espitia-Almeida, F., Díaz-Uribe, C., Vallejo, W., Peña, O., Gómez-Camargo, D., Bohórquez, A. R. R., ... Schott, E. (2021a). Photodynamic effect of 5,10,15,20-tetrakis(4- carboxyphenyl) porphyrin and (Zn²⁺ and Sn⁴⁺) derivatives against Leishmania spp in the promastigote stage: Experimental and DFT study. Chemical Papers, 75(9), 4817–4829. https://doi.org/10.1007/s11696-021-01600-2	eng
dcterms.references	Espitia-Almeida, F., Díaz-Uribe, C., Vallejo, W., Gómez-Camargo, D., RomeroBohorquez, A. R., Schott, E., & Zarate, X. (2019). Synthesis and characterization of 5,10,15,20-tetrakis(4-ethylphenyl) porphyrin and (Zn²⁺, Mn²⁺, Sn²⁺, Ni²⁺, Al³⁺, V³⁺) derivatives: Photophysical and DFT study. ChemistrySelect, 4(20), 6290–6294. https://doi.org/10.1002/slct.201901252	eng
dcterms.references	Espitia-Almeida, F., Vallejo, W., Díaz-Uribe, C., & Gómez-Camargo, D. (2021b). Evaluación fototóxica in vitro de fotosensibilizadores tipo porfirina y metaloporfirina frente a parásitos del género Leishmania. Recuperado de https://www.researchgate.net/publication/351638411	spa
dcterms.references	Espitia-Almeida, F., Valle-Molinares, R., Navarro Quiroz, E., Pacheco-Londoño, L. C., & Galán-Freyle, N. J. (2023). Photodynamic antimicrobial activity of a novel 5,10,15,20- tetrakis(4-ethylphenyl) porphyrin against clinically important bacteria. Pharmaceuticals, 16(8), 1059. https://doi.org/10.3390/ph16081059	eng
dcterms.references	Espitia-Almeida, F., Díaz-Uribe, C., Vallejo, W., Gómez-Camargo, D., Bohórquez, A. R. R., & Linares-Flores, C. (2021c). Photophysical study and in vitro approach against Leishmania panamensis of dicloro-5,10,15,20-tetrakis(4-bromophenyl) porphyrinato Sn(IV). F1000Research, 10, 462. https://doi.org/10.12688/f1000research.52853.1	eng
dcterms.references	Espitia-Almeida, F., Díaz-Uribe, C., Vallejo, W., Gómez-Camargo, D., RomeroBohórquez, A. R., Schott, E., & Zárate, X. (2020). In vitro anti-leishmanial effect of metallic meso-substituted porphyrin derivatives against Leishmania braziliensis and Leishmania panamensis promastigotes properties. Molecules, 25(8), 1887. https://doi.org/10.3390/molecules25081887	eng
dcterms.references	Garcia, F. D. (2020). Síntese, caracterização e estudo fotofísico de novas calcogenoporfirinas derivadas da 5,10,15,20–tetrakis(4-bromometilfenil) porfirina (Tesis doctoral, Universidade Federal de Santa Maria).	ptg
dcterms.references	Goh, Y. M., & Brückner, C. (2007). A metalloporphyrin catalyzed reaction. Inorganic Chemistry, 46(1), 145–156. https://doi.org/10.1021/ic0616354	eng
dcterms.references	Gomes, M.L., Defreitas-Silva, G., Dos Reis, P.G., Melo, M.N., Frézard, F., Demicheli, C., & Idemori, Y.M. (2015). Synthesis and characterization of bismuth(III) and antimony(V) porphyrins: high antileishmanial activity against antimony-resistant parasite. Journal of Biological Inorganic Chemistry. 20(5), 771. https://doi.org/10.1007/s00775-015- 1264-4	eng
dcterms.references	Marin Dawn, Payerpaj Sonia, Collier Graham, Ortiz Angy, Singh Gaurav, Jonesa Marcus, & Walter Michael. (2015). Efficient intersystem crossing using singly halogenated carbomethoxyphenyl porphyrins measured using delayed fluorescence, chemical quenching, and singlet oxygen emission. Phys Chem Chem Phys. 17, 29090. https://doi.org/10.1039/C5CP04359J	eng
dcterms.references	Ortiz et al., 2015 Ortiz Angy, Collier Graham, Marin Dawn, Kassel Jennifer, Ivins Reynolds, Grubicha Nicholas, & Walter Michael. (2014). The effects of heavy atoms on the exciton diffusion properties in photoactive thin films of tetrakis(4- carbomethoxyphenyl)porphyrins. J Mater Chem C. 3, 1243. DOI https://doi.org/10.1039/C4TC02232G	eng
dcterms.references	Tamayo-Carreño, A. P., Espitia-Almeida, F., Díaz-Uribe, C., Vallejo, W., RomeroBohórquez, A. R., Toro-Hernández, R. A., & Henao-Martínez, J. A. (2021). Crystal structure, Hirshfeld surfaces and energy frameworks of 5,10,15,20-tetrakis(4-ethylphenyl) porphyrin. Chemical Data Collections, 32, 100649. https://doi.org/10.1016/j.cdc.2021.100649	eng
dcterms.references	Zheng, W., Shan, N., YU, L., & Wang, X. (2008). UV–visible, fluorescence and EPR properties of porphyrins and metalloporphyrins. Dyes and Pigments. 77(1), 153. https://doi.org/10.1016/j.dyepig.2007.04.007	eng
dcterms.references	Zoltan, T., Vargas, F., López, V., Chávez, V., Rivas, C., & Ramírez, Á. H. (2015). Influence of charge and metal coordination of meso-substituted porphyrins on bacterial photoinactivation. Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy. 135, 747. https://doi.org/10.1016/j.saa.2014.07.053	eng
oaire.version	info:eu-repo/semantics/acceptedVersion
sb.programa	Química y Farmacia	spa
sb.sede	Sede Barranquilla	spa