Seroprevelencia de la infección por dengue en pacientes del Centro de Investigaciones Endocrino-Metabólicas Dr. Félix Gómez, Venezuela
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Fecha
2019
Autores
Gotera, Jennifer Lucila
Valero, Nereida Josefina
Ávila, Ayari Guadalupe
Linares, Johan Carlos
Chacín, Maricarmen
Bermúdez, Valmore
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Editor
Sociedad Venezolana de Farmacología Clínica y Terapéutica
Resumen
Introducción: El dengue un grave problema de salud pública para Venezuela, una infección viral sistémica, autolimitada y transmitida por mosquitos. En los últimos 50 años, a nivel mundial, aumentó la incidencia 30 veces, con circulación de los cuatro serotipos virales. Objetivo: Determinar la seroprevalencia de anticuerpos IgM e IgG contra el virus del dengue en los pacientes que acuden al Instituto de Investigaciones Endocrino-Metabólicas Dr. Félix Gómez, Venezuela. Materiales y Métodos: Se realizó un estudio descriptivo, transversal, donde fueron incluidos 214 individuos sin discriminación de edad y sexo, a los cuales se les tomó una muestra de sangre por venopunción para determinar anticuerpos IgG e IgM contra el virus del dengue. Resultados: La seroprevalencia en la población estudiada de anticuerpos IgG anti dengue fue de 95,7 %; y de anticuerpos IgM de 21,7%. Conclusión: Se evidenció una alta prevalencia de anticuerpos IgG e IgM en la población estudiada. En todos los grupos de edad se encontraron personas seropositivas para IgM. Es necesario impulsar estrategias multisectoriales para el control de la transmisión del dengue.
Introduction: Dengue is a systemic, self-limited and mosqui to-borne viral infection and a serious public health in Venezu ela, In the last 50 years, the worldwide incidence increased 30 times with the four viral serotypes circulation. Objective: To determine the seroprevalence of IgM and IgG antibodies against dengue virus in patients who attend the Endocrine-Metabolic Research Institute Dr. Félix Gómez, Venezuela. Materials and Methods: A descriptive, cross-sectional study was conducted, which included 214 individuals without dis crimination of age and sex, who were taken a blood sample by venipuncture to determine IgG and IgM antibodies against dengue virus. Results: The seroprevalence in the studied population of anti-dengue IgG antibodies was 95.7%; and of 21.7% for IgM antibodies. Conclusion: A high prevalence of IgG and IgM antibodies was evident in the study population. Seropositive people for IgM were found in all age groups. It is necessary to promote multisectoral strategies for the control of dengue transmission.
Introduction: Dengue is a systemic, self-limited and mosqui to-borne viral infection and a serious public health in Venezu ela, In the last 50 years, the worldwide incidence increased 30 times with the four viral serotypes circulation. Objective: To determine the seroprevalence of IgM and IgG antibodies against dengue virus in patients who attend the Endocrine-Metabolic Research Institute Dr. Félix Gómez, Venezuela. Materials and Methods: A descriptive, cross-sectional study was conducted, which included 214 individuals without dis crimination of age and sex, who were taken a blood sample by venipuncture to determine IgG and IgM antibodies against dengue virus. Results: The seroprevalence in the studied population of anti-dengue IgG antibodies was 95.7%; and of 21.7% for IgM antibodies. Conclusion: A high prevalence of IgG and IgM antibodies was evident in the study population. Seropositive people for IgM were found in all age groups. It is necessary to promote multisectoral strategies for the control of dengue transmission.
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Palabras clave
Dengue, Prevalencia, Anticuerpos, Venezuela, Prevalence, Antibodies