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dc.contributor.authorSierra-Castrillo, Jhoalmis
dc.contributor.authorGómez-Rave, Lyz Jenny
dc.contributor.authorChacín-González, Maricarmen
dc.contributor.authorRojas Quintero, Joselyn
dc.contributor.authorBermúdez-Pirela, Valmore
dc.description.abstractLa diabetes mellitus es una de las enfermedades no transmisibles que causa más defunciones a nivel mundial. Cursa con alteraciones en el metabolismo de la glucosa derivadas de la baja disponibilidad de insulina o resistencia a su acción. Estudios recientes indican que hay una relación entre la diabetes mellitus y la disfunción tiroidea, mediada por disturbios en el eje hipotálamo – hipófisis – tiroides, reducción de la actividad deiodinasa, sinergismo de rutas mitogénicas, aumento del estado inflamatorio, el estrés oxidativo y la resistencia a la insulina. La alteración más frecuente es el hipotiroidismo subclínico y se presenta con mayor frecuencia en el sexo femenino por lo que se sugiere realizar periódicamente el perfil tiroideo a estos pacientes. Es necesario que desde la práctica clínica se tengan en cuenta estas implicaciones para brindar un tratamiento oportuno, mejorar complicaciones derivadas como las enfermedades cardiovasculares y disminuir las cifras de
dc.description.abstractDiabetes mellitus is one of the world’s leading non-communicable diseases. It leads to alterations in glucose metabolism due to the low availability of insulin or resistance to its action. Recent studies indicate that there is a relationship between diabetes mellitus and thyroid dysfunction, mediated by disturbances in the hypothalamus - pituitary - thyroid axis, and reduced deiodinase activity, synergism of mitogenic routes, increased inflammatory status, oxidative stress and insulin resistance. The most frequent alteration is subclinical hypothyroidism and it occurs more frequently in women, so it is suggested to periodically perform the thyroid profile to these patients. It is necessary that in clinical practice these implications are taken into account in order to provide timely treatment, improve complications such as cardiovascular disease and reduce morbidity and mortality rates.eng
dc.publisherCooperativa servicios y suministros 212518 RSspa
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.sourceRevista Latinoamericana de Hipertensiónspa
dc.sourceVol. 14, No. 5 (2019)spa
dc.subjectDiabetes mellitus tipo 2spa
dc.subjectDisfunción tiroideaspa
dc.subjectResistencia a la insulinaspa
dc.subjectThyroid dysfunctioneng
dc.titleAlteraciones tiroideas en diabetes mellitus tipo 2spa
dc.title.alternativeThyroid alterations in type 2 diabetes mellituseng
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