Estudio de utilización de antibióticos en Hospitales de Mediana y Alta Complejidad del Departamento del Atlántico-Colombia entre el 2016 y 2017
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Fecha
2018
Autores
Hernández-Gámez, Orison
Camacho-Romero, Oscar
González-Torres, Henry J.
Pajaro-González, Yina
Silva-Castro, Martha Milena
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Editor
Sociedad Venezolana de Farmacología Clínica y Terapéutica
Resumen
Antecedentes: El uso de los agentes antimicrobianos en la
terapéutica de las enfermedades infecciosas, ha constituido
un acontecimiento sin precedentes, este modificó favorablemente
el panorama de la morbilidad y mortalidad del adulto.
Desde hace unos años existe una gran preocupación por el
incremento de la resistencia a los antimicrobianos, por el uso
excesivo de los mismos en la farmacoterapia.
Objetivo: Describir las características de consumo y los patrones
de prescripción de antibióticos(ATB) del grupo J01 en
los hospitales de mediana y alta complejidad del Departamento
del Atlántico en Colombia.
Métodos: Estudio descriptivo-longitudinal durante un año
de estudio (Junio 2016 a Junio 2017). Se evaluaron Diagnósticos,
Antibióticos prescritos, Calidad de la prescripción y
Duración del tratamiento asociados a la prescripción de antibióticos
del grupo J01. Se realizó un censo en cinco clínicas
del Departamento del Atlántico.
Resultados: Se realizó seguimiento a 8241 pacientes con
tratamiento antibiótico del grupo J01, durante el periodo de
doce (12) meses del estudio. Se identificaron 38 antibióticos
en 12465 prescripciones durante el año de estudio, con al
menos un antibiótico de uso sistémico. La cefredina fue el
antibiótico con mayor porcentaje de prescripciones realizadas,
seguido de las penicilinas. Solo 59,4% de las prescripciones
de antibióticos fueron evaluadas como prescripción
adecuada. La duración del tratamiento antibiótico, 61,2%
tuvo un periodo de uso del antibiótico entre 1 y 5 días, seguida
por el 24,9% que duro entre 6 y 10 días.
Conclusión: Los antibióticos más prescritos corresponden a
cefalosporinas de primera y tercera generación, seguido de
los inhibidores de penicilina+inhibidores de beta-lactamasas.
Background: The use of antimicrobial agents in the treatment of infectious diseases, has been an unprecedented event, this favorably changed the panorama of adult morbidity and mortality. For some years there has been a great concern about the increase in resistance to antimicrobials, due to the excessive use of them in pharmacotherapy. Objective: To describe the characteristics of consumption and prescription patterns of antibiotics (ATB) of group J01 in medium and high complexity hospitals of the Department of Atlántico in Colombia. Methods: Descriptive-longitudinal study during one year of study (June 2016 to June 2017). Diagnostics, prescribed antibiotics, quality of the prescription and duration of treatment associated with the prescription of antibiotics of group J01 were evaluated. A census was conducted in five clinics of the Department of Atlántico. Results: 8241 patients were followed up with antibiotic treatment of group J01, during the twelve (12) month period of the study. 38 antibiotics were identified in 12465 prescriptions during the study year, with at least one antibiotic for systemic use. Cefredine was the antibiotic with the highest percentage of prescriptions performed, followed by penicillins. Only 59.4% of antibiotic prescriptions were evaluated as an adequate prescription. The duration of antibiotic treatment, 61.2% had a period of antibiotic use between 1 and 5 days, followed by 24.9% that lasted between 6 and 10 days. Conclusion: The most prescribed antibiotics correspond to first and third generation cephalosporins, followed by penicillin inhibitors + beta-lactamase inhibitors.
Background: The use of antimicrobial agents in the treatment of infectious diseases, has been an unprecedented event, this favorably changed the panorama of adult morbidity and mortality. For some years there has been a great concern about the increase in resistance to antimicrobials, due to the excessive use of them in pharmacotherapy. Objective: To describe the characteristics of consumption and prescription patterns of antibiotics (ATB) of group J01 in medium and high complexity hospitals of the Department of Atlántico in Colombia. Methods: Descriptive-longitudinal study during one year of study (June 2016 to June 2017). Diagnostics, prescribed antibiotics, quality of the prescription and duration of treatment associated with the prescription of antibiotics of group J01 were evaluated. A census was conducted in five clinics of the Department of Atlántico. Results: 8241 patients were followed up with antibiotic treatment of group J01, during the twelve (12) month period of the study. 38 antibiotics were identified in 12465 prescriptions during the study year, with at least one antibiotic for systemic use. Cefredine was the antibiotic with the highest percentage of prescriptions performed, followed by penicillins. Only 59.4% of antibiotic prescriptions were evaluated as an adequate prescription. The duration of antibiotic treatment, 61.2% had a period of antibiotic use between 1 and 5 days, followed by 24.9% that lasted between 6 and 10 days. Conclusion: The most prescribed antibiotics correspond to first and third generation cephalosporins, followed by penicillin inhibitors + beta-lactamase inhibitors.
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Palabras clave
Consumo de Antibióticos, Comportamiento de prescripción, Profilaxis con antibióticos, Resistencia microbiana a los medicamentos, Antibiotic Consumption, Prescribing behavior, Antibiotic Prophylaxis, Microbial Drug Resistance