Detección de anomalías celulares en mujeres que asisten al control citológico en la liga contra el cáncer en Barranquilla
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Fecha
2016
Autores
Castillo Álvarez, Daniela Melisa
David González, Amet Jesús
Pupo Lara, Jairo Andrés
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Ediciones Universidad Simón Bolívar
Facultad de Ciencias de la Salud
Facultad de Ciencias de la Salud
Resumen
A nivel mundial, anualmente se diagnostican 530.000 casos nuevos de cáncer
cervicouterino (CaCu) presentándose cifras altas de incidencia e incrementando
las tasas de morbilidad y mortalidad. Se ha establecido que el principal factor
etiológico de la causa del CaCu es la infección de diferentes tipos de virus
oncogénicos como el virus del papiloma humano (VPH) en su mayor prevalencia
los tipos 16 y 18.
Para la detección de lecciones escamosas intraepiteliales de alto y bajo grado,
tradicionalmente se ha implementado el test de Papanicolaou, con excelentes
resultados. La presente investigación se llevó a cabo en mujeres que asistieron a
control citológico en la Liga contra el Cáncer de Barranquilla, para determinar la
presencia de algunas anomalías celulares no detectadas en Papanicolaou, y de
algunos biomarcadores llamados micronúcleos los cuales están validados como
indicadores de riesgo de padecer cáncer en humanos.
Globally, every year 530,000 new cases of cervical cancer are diagnosed presenting high rates of incidence and increasing rates of morbidity and mortality. lt has been established that the main etiological factor of the cause of cervical cancer is infection of different types of oncogenic viruses like human papillomavirus (HPV) the most prevalent types 16 and 18. For detection of squamous intraepithelial lessons of high and low grade, traditionally it has been implemented Pap test with excellent results. This research was conducted in women who attended cytological screening in the Cancer League of Barranquilla, to determine the presence of certain cellular abnormalities not detected on Pap smears, and sorne biomarkers called micronuclei which are validated as risk of cancer in humans.
Globally, every year 530,000 new cases of cervical cancer are diagnosed presenting high rates of incidence and increasing rates of morbidity and mortality. lt has been established that the main etiological factor of the cause of cervical cancer is infection of different types of oncogenic viruses like human papillomavirus (HPV) the most prevalent types 16 and 18. For detection of squamous intraepithelial lessons of high and low grade, traditionally it has been implemented Pap test with excellent results. This research was conducted in women who attended cytological screening in the Cancer League of Barranquilla, to determine the presence of certain cellular abnormalities not detected on Pap smears, and sorne biomarkers called micronuclei which are validated as risk of cancer in humans.
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Palabras clave
Riesgo, Micronúcleos, Cáncer Cervicouterino, Citoma, Citología, Risk, Micronuclei, Cervical Cancer, Cytology, Cytoma