Alfaro Eraso, LeidyAlemán García, DanielaFernández Mercado, RobinsonLlinás, FedericoDiaz-Yunez, IsraelDe Nubila, EduardoFranco Novella, Hernando2025-01-312025-01-3120242407-9529 (Electrónico)2408-0071 (Impreso)https://hdl.handle.net/20.500.12442/16188To evaluate the effectiveness of mammography and breast ultrasound in the detection of lesions suspicious of breast cancer (BI-RADS 4 and 5). This cross-sectional study examined 315 cases involving mammographic and ultrasound reports categorised as BI-RADS 4 or 5. These cases underwent image-guided biopsies between 2018 and 2023. Cases involving radiotherapy or chemotherapy were excluded. Data were collected from medical histories and pathology reports from biopsies. The following variables were recorded: age; BI-RADS classification; type of study; and histological type. Descriptive statistics were used and chi-square tests were performed. Statistical significance was considered at p < 0.05. Of the BI-RADS 4 cases, 28.78% were classified by ultrasound and 90% by digital mammography. Seventy-one point twenty-two percent of BI-RADS 5 were detected by ultrasound and 10% by digital mammography. Ultrasound detected 80.98% (n = 166) of malignant cases. Digital mammography identified 23.64% (n = 26) of malignant cases. In subcategory 4A, 13 out of 70 cases (18.5%) were confirmed as cancerous, with a 95% confidence interval (CI) of 10.2% to 29.6%. For BIRADS 4B: In subcategory 4B, 14 out of 70 cases (20.0%) were found to be cancerous, with a 95% confidence interval (CI) ranging from 11.3% to 31.2%. In subcategory 4C, 15 out of 18 cases (83.3%) were confirmed as cancerous, with a 95% confidence interval (CI) ranging from 58.5% to 96.4%. Finally, for the BIRADS 5 category: Of the 157 cases classified as BIRADS 5, 95.5% (150 cases) were found to be cancerous, with a 95% CI ranging from 91% to 98%. Overall, 73.42% (n = 116) of BI-RADS 4 cases were benign, while 95.54% (n = 150) of BI-RADS 5 cases were malignant. The cancer detection rate by ultrasound for BIRADS 4 was 41%, compared to 16.1% for mammography. Ultrasound detected 95.8% of the total number of patients with BIRADS-5, and mammography detected 90.9%. Conclusion: BI-RADS category 5 offers high diagnostic predictability, whereas BI-RADS category 4 still yields a high number of false positives, primarily within subcategories 4a and 4b. Combining ultrasound and digital mammography improves the overall diagnostic capacity.pdfspaAttribution-NonCommercial-NoDerivs 3.0 United Statesinfo:eu-repo/semantics/embargoedAccessinfo:eu-repo/semantics/other10.5281/zenodo.121.126276https://sci-cult.net/index.php/cult/article/view/3184/1921Breast cancerDigital mammographyBreast ultrasoundEffectivenessDiagnosisBiopsyBI-RADS 4BI-RADS 5