Efecto Agudo De La Melatonina Exógena Sobre Funciones Cognitivas, En Jóvenes Adultos Que Consumen Alcohol
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Fecha
2018
Autores
Sánchez-Betancourt, Javier
Avila-Costa, María Rosa
Meza-Amaya, Arturo
Ruiz-Vazquez, Jorge
Muñiz-Salazar, Raquel
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Sociedad Venezolana de Farmacología Clínica y Terapéutica
Resumen
La melatonina es una neurohormona asociada con los ciclos del sueño y como barredor de radicales libres. Recientemente, se ha demostrado que es eficaz para proteger el hipocampo en condiciones de estrés oxidativo, reduciendo el daño celular y promoviendo mejores ejecuciones en las pruebas de memoria. En este estudio, se evaluó si el consumo diario de 10 mg de melatonina podría tener efectos favorables sobre la memoria y el pensamiento abstracto en adultos jóvenes que consumían alcohol. Los participantes fueron evaluados con las pruebas de Memory span y con la prueba de tarjetas de Wisconsin. Los resultados mostraron que el consumo exógeno de melatonina se asoció con una mejora significativa en funciones cognitivas, aun en condiciones de consumo regular de alcohol.
Melatonin is a neurohormone associated with sleep cycles and free radical scavenger. Recently, it has been shown to be effective in protecting the hippocampus under stress conditions, reducing cell damage and promoting better executions in memory tests. In this study, it was tested whether the daily consumption of 10 mg of melatonin could have favorable effects on memory and abstract thinking in adults who consumed alcohol. The participants were evaluated with the "Memory Span" and Wisconsin cards test, The results showed that exogenous melatonin consumption was associated with a significant improvement in cognitive functions, even when alcohol is consumed regularly
Melatonin is a neurohormone associated with sleep cycles and free radical scavenger. Recently, it has been shown to be effective in protecting the hippocampus under stress conditions, reducing cell damage and promoting better executions in memory tests. In this study, it was tested whether the daily consumption of 10 mg of melatonin could have favorable effects on memory and abstract thinking in adults who consumed alcohol. The participants were evaluated with the "Memory Span" and Wisconsin cards test, The results showed that exogenous melatonin consumption was associated with a significant improvement in cognitive functions, even when alcohol is consumed regularly
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Palabras clave
Melatonina, Alcoholismo, Memoria, Pensamiento abstracto, Hipocampo, Melatonin, Alcoholism, Memory, Abstract thinking, Hippocampus