Purpose of Review. Stevia rebaudiana Bertoni is a perennial shrub with zero calorie content that has been increasing in popularity for its potential use as an adjuvant in the treatment of obesity. The level of evidence supporting general benefits to human health is insufficient. We conducted a review of the literature summarizing the current knowledge and role in human disease. Recent Findings. Despite stevia’s minimal systemic absorption, studies have been promising regarding its potential benefits against inflammation, carcinogenesis, ...