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Biochemical and clinical characterization of metabolic phenotypes: a cross-sectional study from Maracaibo city, Venezuela [version 1; referees: awaiting peer review]
(is published by F1000 Research Ltd, 2018-02)
Background: In 1980, Reuben Andresen observed that in certain individuals,
obesity did not increase mortality, introducing an atypical phenotype called
“healthy obese”. Other studies reported that 10-15 % of lean individuals
presented insulin resistance, hyperglycemia and dyslipidemia. The objective of
this study was to evaluate biochemical and clinical characteristics of metabolic
phenotypes in Maracaibo city.
Methods: A descriptive, cross-sectional study with a randomized multistage
sampling was performed including 1226 non diabetic ...