Buscar
Mostrando ítems 1-10 de 12
Metabolic Syndrome and Subclinical Hypothyroidism: A Type 2 Diabetes-Dependent Association
(Hindawi, 2018)
Introduction. Subclinical hypothyroidism (ScH) is an endocrine alteration that is related to cardiovascular risk factors, including those categorized as components of the Metabolic Syndrome (MS). However, findings in prior reports regarding an association between these alterations are inconsistent. The purpose of this study was to determine the relationship between both entities in adult subjects from Maracaibo City, Venezuela. Materials and Methods. The Maracaibo City Metabolic Syndrome Prevalence Study is a descriptive, cross-sectional study ...
Obesidad Infantil: Un problema de pequeños que se está volviendo grande
(Cooperativa servicios y suministros 212518 RS, 2019)
La obesidad es una enfermedad crónica de comportamiento epidemiológico complejo
que se origina de la interacción entre factores genéticos y ambientales, entre los que destacan los patrones de alimentación y el consumo calórico diario, así como el grado de actividad física. Según la Organización Mundial para la Salud (OMS), la obesidad se define como una
acumulación anormal y excesiva de grasa corporal. Para el diagnóstico de esta condición en niños y adolescentes se utilizan tablas diseñadas por la OMS que definen a un individuo con sobrepeso ...
Microbiota and Diabetes Mellitus: Role of Lipid Mediators
(MDPI, 2020)
Diabetes Mellitus (DM) is an inflammatory clinical entity with different mechanisms involved in its physiopathology. Among these, the dysfunction of the gut microbiota stands out. Currently, it is understood that lipid products derived from the gut microbiota are capable of interacting with cells from the immune system and have an immunomodulatory effect. In the presence of dysbiosis, the concentration of lipopolysaccharides (LPS) increases, favoring damage to the intestinal barrier. Furthermore, a pro-inflammatory environment prevails, and a ...
Prevalence of physical inactivity and associated cardiometabolic risk factors: A cross-sectional study
(Saber UCV, Universidad Central de Venezuela, 2020)
Physical inactivity represents a public health problem associated with non-communicable diseases. This study aimed to determine both general and domain-specific prevalence of physical inactivity as well as its association with cardiometabolic factors. Methods: A cross-sectional study was performed, including 2 230 adult individuals from both sexes from Maracaibo city.
Análisis clínico-epidemiológico de las subfracciones HDL2 y HDL3 en adultos de la ciudad de Maracaibo, Venezuela
(Instituto Nacional de Salud. Lima, Perú, 2020)
Objetivo: Realizar un análisis clínico-epidemiológico de las subfracciones de colesterol unido a lipoproteinas de alta densidad (HDL-C, por sus siglas en inglés) en adultos de la ciudad de Maracaibo, Venezuela. Materiales y métodos: Se realizó un estudio descriptivo y transversal de la base de datos del Estudio de Prevalencia de Síndrome Metabólico de Maracaibo, que incluyó 359 individuos de ambos sexos, mayores de 18 años, a quienes se les determinó la concentración sérica de HDL3 y HDL2, así como el índice HDL2/ HDL3; evaluando sus niveles según ...
Metabolic Syndrome: Is It Time to Add the Central Nervous System?
(MDPI, 2021-06)
Metabolic syndrome (MS) is a set of cardio-metabolic risk factors that includes central obesity, hyperglycemia, hypertension, and dyslipidemias. The syndrome affects 25% of adults worldwide. The definition of MS has evolved over the last 80 years, with various classification systems and criteria, whose limitations and benefits are currently the subject of some controversy. Likewise, hypotheses regarding the etiology of MS add more confusion from clinical and epidemiological points of view. The leading suggestion for the pathophysiology of MS is ...
Advanced Glycation End Products: New Clinical and Molecular Perspectives
(MDPI, 2021)
Diabetes mellitus (DM) is considered one of the most massive epidemics of the twenty-first century due to its high mortality rates caused mainly due to its complications; therefore, the early identification of such complications becomes a race against time to establish a prompt diagnosis. The research of complications of DM over the years has allowed the development of numerous alternatives for diagnosis. Among these emerge the quantification of advanced glycation end products (AGEs) given their increased levels due to chronic hyperglycemia, while ...
Lipid Accumulation Product Is More Related to Insulin Resistance than the Visceral Adiposity Index in the Maracaibo City Population, Venezuela
(Hindawi, 2021)
Background. Visceral adiposity is related to insulin resistance (IR), a metabolic state considered as a risk factor for other cardiometabolic diseases. In that matter, mathematical indexes such as the visceral adiposity index (VAI) and the lipid accumulation product (LAP) could indirectly assess IR based on visceral adiposity. Objective. To evaluate the association and diagnostic accuracy of VAI and LAP to diagnose IR in the adult population of Maracaibo city. Methods. This is a cross-sectional descriptive study with multistage sampling. Receiver ...
The Role of the α Cell in the Pathogenesis of Diabetes: A World beyond the Mirror
(MDPI, 2021)
Type 2 Diabetes Mellitus (T2DM) is one of the most prevalent chronic metabolic disorders, and insulin has been placed at the epicentre of its pathophysiological basis. However, the involvement of impaired alpha (α) cell function has been recognized as playing an essential role in several diseases, since hyperglucagonemia has been evidenced in both Type 1 and T2DM. This phenomenon has been attributed to intra-islet defects, like modifications in pancreatic α cell mass or dysfunction in glucagon’s secretion. Emerging evidence has shown that chronic ...
Prevalencia de sobrepeso y obesidad en escolares de San José de Cúcuta, Norte de Santander, Colombia
(Saber UCV, Universidad Central de Venezuela, 2020)
Introducción y Objetivo: El sobrepeso y la obesidad infantil son problemas de salud emergentes en países con un estilo de vida occidental tanto en la niñez como en edad adulta. Debido a la escasa información sobre este tema en nuestra comunidad, el objetivo de este estudio fue determinar la prevalencia de sobrepeso y obesidad en niños de la ciudad de San José de Cúcuta, Colombia.
Materiales y Métodos: estudio piloto de tipo no experimental y transversal con un muestreo no probabilístico, donde se incluyeron escolares con edades comprendidas ...