• Engineering a single-chain antibody against Trypanosoma cruzi metacyclic trypomastigotes to block cell invasion 

      Kalempa Demeu, Lara Maria; Jahn Soares, Rodrigo; Severo Miranda, Juliana; Pacheco-Lugo, Lisandro A.; Gonçalves Oliveira, Kelin; Cortez Plaza, Cristian Andrés; Billiald, Philippe; Ferreira de Moura, Juliana; Yoshida, Nobuko; Magalhães Alvarenga, Larissa; Duarte DaRocha, Wanderson (Javier Marcelo Di Noia, Institut de recherches cliniques de Montreal, CANADA, 2019-10)
      Trypanosoma cruzi is a flagellate protozoan pathogen that causes Chagas disease. Currently there is no preventive treatment and the efficiency of the two drugs available is limited to the acute phase. Therefore, there ...