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Metabolic Syndrome and Subclinical Hypothyroidism: A Type 2 Diabetes-Dependent Association
(Hindawi, 2018)
Introduction. Subclinical hypothyroidism (ScH) is an endocrine alteration that is related to cardiovascular risk factors, including those categorized as components of the Metabolic Syndrome (MS). However, findings in prior reports regarding an association between these alterations are inconsistent. The purpose of this study was to determine the relationship between both entities in adult subjects from Maracaibo City, Venezuela. Materials and Methods. The Maracaibo City Metabolic Syndrome Prevalence Study is a descriptive, cross-sectional study ...
Optimal cutoff for the evaluation of insulin resistance through triglyceride-glucose index: A cross-sectional study in a Venezuelan population [version 1; referees: awaiting peer review]
(F1000 Research Ltd., 2017-08-07)
Background: Insulin resistance (IR) evaluation is a fundamental goal in clinical
and epidemiological research. However, the most widely used methods are
difficult to apply to populations with low incomes. The triglyceride-glucose index
(TGI) emerges as an alternative to use in daily clinical practice. Therefore the
objective of this study was to determine an optimal cutoff point for the TGI in an
adult population from Maracaibo, Venezuela.
Methods: This is a sub-study of Maracaibo City Metabolic Syndrome
Prevalence Study, a descriptive, ...
Biochemical and clinical characterization of metabolic phenotypes: a cross-sectional study from Maracaibo city, Venezuela [version 1; referees: awaiting peer review]
(is published by F1000 Research Ltd, 2018-02)
Background: In 1980, Reuben Andresen observed that in certain individuals,
obesity did not increase mortality, introducing an atypical phenotype called
“healthy obese”. Other studies reported that 10-15 % of lean individuals
presented insulin resistance, hyperglycemia and dyslipidemia. The objective of
this study was to evaluate biochemical and clinical characteristics of metabolic
phenotypes in Maracaibo city.
Methods: A descriptive, cross-sectional study with a randomized multistage
sampling was performed including 1226 non diabetic ...
Insulin resistance indices and coronary risk in adults from Maracaibo city, Venezuela: A cross sectional study [version 1; referees: 1 approved with reservations]
(is published by F1000 Research Ltd, 2018-03)
Background: Insulin resistance (IR) is a metabolic disorder related to
atherosclerosis. Its measurement is of great importance not only as a marker of
diabetes but also for cardiovascular disease. The aim of this research study
was to evaluate the relationship between various IR indices and coronary risk in
an adult population from Maracaibo city, Venezuela.
Methods: The Maracaibo City Metabolic Syndrome Prevalence Study is a
descriptive, cross-sectional study with random and multi-stage sampling. In this
sub study, 1272 individuals of ...
Cigarette smoking and metabolic syndrome components: a cross-sectional study from Maracaibo City, Venezuela [version 1; referees: 1 approved with reservations]
(F1000 Research Ltda, 2018-05-22)
Background: A growing body of evidence suggests that cigarette smoking can
cause the onset of metabolic syndrome prior to cardiovascular diseases.
Therefore, the objective of this study was to evaluate the relationship between
smoking habit and metabolic syndrome components in an adult population from
Maracaibo city, Venezuela.
Methods: The Maracaibo City Metabolic Syndrome Prevalence Study is a
descriptive, cross-sectional study with random and multi-stage sampling. In this
sub-study, 2212 adults from both genders were selected. On the ...
Una introducción a las aplicaciones de la inteligencia artificial en Medicina: Aspectos históricos
(Cooperativa servicios y suministros 212518 RS, 2019)
En un sentido amplio la inteligencia artificial y el aprendizaje automático se ha aplicado a los datos médicos desde los inicios de la informática dado el profundo arraigo de esta área en la innovación, pero los últimos años han sido testigo de una
generación cada vez mayor de datos relacionados con las ciencias de la salud, cuestión que ha dado nacimiento a un nuevo campo de las ciencias de la computación llamado big data. Los datos médicos a gran escala (en forma
de bases de datos estructuradas y no estructuradas) si son apropiadamente ...
Pyoderma gangrenosum in a patient with type 2 diabetes: a case report
(Universidad del Zulia, 2020)
We are presenting a case of patient with type 2 diabetes mellitus that was diagnosed with a soft tissue infection in the lower extremity. This was initially treated as cellulitis and antibiotic treatment was initiated. Due to a poor clinical response, the diagnosis of pyoderma gangrenosum was proposed as part of the differential diagnosis. Skin biopsies and pathology confirmed the diagnosis of pyoderma gangrenosum that had a satisfactory response to steroid treatment.
Obesidad Infantil: Un problema de pequeños que se está volviendo grande
(Cooperativa servicios y suministros 212518 RS, 2019)
La obesidad es una enfermedad crónica de comportamiento epidemiológico complejo
que se origina de la interacción entre factores genéticos y ambientales, entre los que destacan los patrones de alimentación y el consumo calórico diario, así como el grado de actividad física. Según la Organización Mundial para la Salud (OMS), la obesidad se define como una
acumulación anormal y excesiva de grasa corporal. Para el diagnóstico de esta condición en niños y adolescentes se utilizan tablas diseñadas por la OMS que definen a un individuo con sobrepeso ...
Microbiota and Diabetes Mellitus: Role of Lipid Mediators
(MDPI, 2020)
Diabetes Mellitus (DM) is an inflammatory clinical entity with different mechanisms involved in its physiopathology. Among these, the dysfunction of the gut microbiota stands out. Currently, it is understood that lipid products derived from the gut microbiota are capable of interacting with cells from the immune system and have an immunomodulatory effect. In the presence of dysbiosis, the concentration of lipopolysaccharides (LPS) increases, favoring damage to the intestinal barrier. Furthermore, a pro-inflammatory environment prevails, and a ...
Análisis clínico-epidemiológico de las subfracciones HDL2 y HDL3 en adultos de la ciudad de Maracaibo, Venezuela
(Instituto Nacional de Salud. Lima, Perú, 2020)
Objetivo: Realizar un análisis clínico-epidemiológico de las subfracciones de colesterol unido a lipoproteinas de alta densidad (HDL-C, por sus siglas en inglés) en adultos de la ciudad de Maracaibo, Venezuela. Materiales y métodos: Se realizó un estudio descriptivo y transversal de la base de datos del Estudio de Prevalencia de Síndrome Metabólico de Maracaibo, que incluyó 359 individuos de ambos sexos, mayores de 18 años, a quienes se les determinó la concentración sérica de HDL3 y HDL2, así como el índice HDL2/ HDL3; evaluando sus niveles según ...