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Automatic segmentation of a cerebral glioblastoma using a smart computational technique
(Sociedad Venezolana de Farmacología Clínica y Terapéutica, 2018)
We propose an intelligent computational technique for the
image segmentation of a type IV brain tumor, identified as
multiform glioblastoma (MGB), which is present in multi-layer
computed tomography images. This technique consists of
3 stages developed in the three-dimensional domain. They
are: pre-processing, segmentation and validation. During the
validation stage, the Dice coefficient (Dc) is considered in
order to compare the segmentations of the MGB, obtained
automatically, with the segmentations of the MGB generated
manually, by a ...
Smoothing filters in synthetic cerebral magnetic resonance images: A comparative study
(Sociedad Latinoamericana de Hipertensión, 2018)
This paper presents the evaluation of two computational
techniques for smoothing noise that might be present
in synthetic images or numerical phantoms of magnetic
resonance (MRI). The images that will serve as the databases
(DB) during the course of this evaluation are available
freely on the Internet and are reported in specialized
literature as synthetic images called BrainWeb. The
images that belong to this DB were contaminated with
Rician noise, this being the most frequent type of noise
in real MRI images. Also, the techniques that ...
Aproximación al uso de interfaz gráfica en la operatividad de agentes inteligentes con imágenes médicas
(Sociedad Venezolana de Farmacología Clínica y Terapéutica, 2019)
En el presente artículo se da a conocer el estado del arte relativo al desarrollo de interfaz gráfica de usuario para la integración de técnicas de procesamiento de imágenes y operadores basados en máquinas inteligentes, orientada a la construcción de enfoques computacionales útiles en la rutina clínica y/o en la investigación relacionada con el diagnóstico de neoplasias malignas en el sistema gastrointestinal. Para ello, inicialmente se contextualiza a través de una fundamentación teórica la interfaz gráfica en el contexto de las imágenes médicas, ...
La realidad virtual como herramienta en el proceso de aprendizaje del cerebro
(Sociedad Venezolana de Farmacología Clínica y Terapéutica, 2019)
En este artículo se presenta el estudio del cerebro y otras aplicaciones clínicas mediante las herramientas de navegación de la realidad virtual (RV), la capacidad de captar la interacción real por medio de imágenes en 3D, proyectadas a través
de un neuronavegador, entendiéndose por neuronavegación a la producción de imágenes por medio de un programa que sirva como herramienta diagnóstica o terapéutica en neurocirugía u otras áreas médico-quirúrgicas, basándose en un
sistema informático que permite visualizar y dar seguimiento mediante un ...
Pyoderma gangrenosum in a patient with type 2 diabetes: a case report
(Universidad del Zulia, 2020)
We are presenting a case of patient with type 2 diabetes mellitus that was diagnosed with a soft tissue infection in the lower extremity. This was initially treated as cellulitis and antibiotic treatment was initiated. Due to a poor clinical response, the diagnosis of pyoderma gangrenosum was proposed as part of the differential diagnosis. Skin biopsies and pathology confirmed the diagnosis of pyoderma gangrenosum that had a satisfactory response to steroid treatment.
Perirenal fat thickness is associated with metabolic risk factors in patients with chronic kidney disease
(The Korean Society of Nephrology, 2019)
Adipose tissue accumulation in specific body compartments has been associated with diabetes, hypertension and dyslipidemia. Perirenal fat (PRF) may lead to have direct lipotoxic effects on renal function and intrarenal hydrostatic pressure. This study was undertaken to explore the association of PRF with cardiovascular risk factors and different stages of chronic kidney disease (CKD). We studied 103 patients with CKD of different stages (1 to 5). PRF was measured by B-mode renal ultrasonography in the distal third between the cortex and the hepatic ...
Obesidad Infantil: Un problema de pequeños que se está volviendo grande
(Cooperativa servicios y suministros 212518 RS, 2019)
La obesidad es una enfermedad crónica de comportamiento epidemiológico complejo
que se origina de la interacción entre factores genéticos y ambientales, entre los que destacan los patrones de alimentación y el consumo calórico diario, así como el grado de actividad física. Según la Organización Mundial para la Salud (OMS), la obesidad se define como una
acumulación anormal y excesiva de grasa corporal. Para el diagnóstico de esta condición en niños y adolescentes se utilizan tablas diseñadas por la OMS que definen a un individuo con sobrepeso ...
Prevalence of physical inactivity and associated cardiometabolic risk factors: A cross-sectional study
(Saber UCV, Universidad Central de Venezuela, 2020)
Physical inactivity represents a public health problem associated with non-communicable diseases. This study aimed to determine both general and domain-specific prevalence of physical inactivity as well as its association with cardiometabolic factors. Methods: A cross-sectional study was performed, including 2 230 adult individuals from both sexes from Maracaibo city.
Microbiota and Diabetes Mellitus: Role of Lipid Mediators
(MDPI, 2020)
Diabetes Mellitus (DM) is an inflammatory clinical entity with different mechanisms involved in its physiopathology. Among these, the dysfunction of the gut microbiota stands out. Currently, it is understood that lipid products derived from the gut microbiota are capable of interacting with cells from the immune system and have an immunomodulatory effect. In the presence of dysbiosis, the concentration of lipopolysaccharides (LPS) increases, favoring damage to the intestinal barrier. Furthermore, a pro-inflammatory environment prevails, and a ...
Is “Leptin Resistance” Another Key Resistance to Manage Type 2 Diabetes?
(Bentham Science Publishers, 2020)
Although novel pharmacological options for the treatment of type 2 diabetes mellitus (DM2) have been observed to modulate the functionality of several key organs in glucose homeostasis, successful regulation of insulin resistance (IR), body weight management, and pharmacological treatment of obesity remain notable problems in endocrinology. Leptin may be a pivotal player in this scenario, as an adipokine which centrally regulates appetite and energy balance. In obesity, excessive caloric intake promotes a low-grade inflammatory response, which ...