Buscar
Mostrando ítems 1-2 de 2
Data Mining and Endocrine Diseases: A New Way to Classify?
(Elsevier, 2018-04)
Data mining consists of using large database analysis to detect patterns, relationships and
models in order to describe (or even predict) the appearance of a future event; to accomplish
this, it uses classification methods, rules of association, regression patterns, link and
cluster analyses. Recently this approach has been used to propose a new diabetes mellitus
classification, using information analysis techniques through which the selection bias
minimally influences categorization, this new focus that includes data mining previously
implemented ...
Is “Leptin Resistance” Another Key Resistance to Manage Type 2 Diabetes?
(Bentham Science Publishers, 2020)
Although novel pharmacological options for the treatment of type 2 diabetes mellitus (DM2) have been observed to modulate the functionality of several key organs in glucose homeostasis, successful regulation of insulin resistance (IR), body weight management, and pharmacological treatment of obesity remain notable problems in endocrinology. Leptin may be a pivotal player in this scenario, as an adipokine which centrally regulates appetite and energy balance. In obesity, excessive caloric intake promotes a low-grade inflammatory response, which ...