Introduction. Subclinical hypothyroidism (ScH) is an endocrine alteration that is related to cardiovascular risk factors, including those categorized as components of the Metabolic Syndrome (MS). However, findings in prior reports regarding an association between these alterations are inconsistent. The purpose of this study was to determine the relationship between both entities in adult subjects from Maracaibo City, Venezuela. Materials and Methods. The Maracaibo City Metabolic Syndrome Prevalence Study is a descriptive, cross-sectional study ...

Introducción: La obesidad se considera una epidemia global, cuya prevalencia se estima que aumente drásticamente en los próximos años. Por otra parte, la actividad física ha demostrado múltiples beneficios, entre los cuales se encuentran el ser un factor protector de riesgo cardiometabólico. Sin embargo en las parroquias rurales de Cuenca-Ecuador no se ha evaluado el impacto que tiene la actividad física sobre la obesidad. Materiales y métodos: Se realizó un estudio de campo, descriptivo y transversal en 530 individuos mayores a 18 años ...

El alcohol es una sustancia que ha generado alto impacto en la salud pública y daños cognitivos. El objetivo es describir las diferencias existentes en el desempeño cognitivo, de estudiantes universitarios según el grado de consumo de alcohol. Por lo cual, se realizó un estudio descriptivo-comparativo, de corte transversal con 43 estudiantes universitarios divido en tres grupos según el patrón de consumo. Se implementó el AUDIT y un protocolo neuropsicológico. No se evidenciaron diferencias estadísticamente significativas entre los distintos ...

Background: Adrenal incidentaloma refers to the incidental finding of a tumor in the adrenal gland, where nonfunctional forms are the most common variant. Myelolipoma is a rare (0.08-0.4%) occurrence characterized by adipose and hematopoietic tissue. The aim of this case report is to describe the diagnosis and appropriate management of a myelolipoma in an asymptomatic patient, which was originally considered an incidental hepatic hemangioma prior to being identified as a giant adrenal adenoma. Case description: The patient was a 54 year ...

Background: Insulin resistance (IR) evaluation is a fundamental goal in clinical and epidemiological research. However, the most widely used methods are difficult to apply to populations with low incomes. The triglyceride-glucose index (TGI) emerges as an alternative to use in daily clinical practice. Therefore the objective of this study was to determine an optimal cutoff point for the TGI in an adult population from Maracaibo, Venezuela. Methods: This is a sub-study of Maracaibo City Metabolic Syndrome Prevalence Study, a descriptive, ...

Background: Insulin resistance (IR) is a metabolic disorder related to atherosclerosis. Its measurement is of great importance not only as a marker of diabetes but also for cardiovascular disease. The aim of this research study was to evaluate the relationship between various IR indices and coronary risk in an adult population from Maracaibo city, Venezuela. Methods: The Maracaibo City Metabolic Syndrome Prevalence Study is a descriptive, cross-sectional study with random and multi-stage sampling. In this sub study, 1272 individuals of ...

We are presenting a case of patient with type 2 diabetes mellitus that was diagnosed with a soft tissue infection in the lower extremity. This was initially treated as cellulitis and antibiotic treatment was initiated. Due to a poor clinical response, the diagnosis of pyoderma gangrenosum was proposed as part of the differential diagnosis. Skin biopsies and pathology confirmed the diagnosis of pyoderma gangrenosum that had a satisfactory response to steroid treatment.

Introducción: El hiperparatiroidismo primario es el aumento en los niveles de paratohormona (PTH), su cuadro clínico se caracteriza por síntomas de hipercalcemia, nefrolitiasis, enfermedad mineral ósea, síntomas neuromusculares, también existen cuadros asintomáticos; la nefrolitiasis ocurre en un 4 a 15% de los pacientes, y esta enfermedad suele aparecer en mujeres en la menopausia. Caso Clínico: Paciente femenina de 65 años de edad, que presenta cuadro clínico caracterizado por dolor en hipogastrio de leve intensidad que se irradia a región ...

La obesidad es una enfermedad crónica de comportamiento epidemiológico complejo que se origina de la interacción entre factores genéticos y ambientales, entre los que destacan los patrones de alimentación y el consumo calórico diario, así como el grado de actividad física. Según la Organización Mundial para la Salud (OMS), la obesidad se define como una acumulación anormal y excesiva de grasa corporal. Para el diagnóstico de esta condición en niños y adolescentes se utilizan tablas diseñadas por la OMS que definen a un individuo con sobrepeso ...

Diabetes Mellitus (DM) is an inflammatory clinical entity with different mechanisms involved in its physiopathology. Among these, the dysfunction of the gut microbiota stands out. Currently, it is understood that lipid products derived from the gut microbiota are capable of interacting with cells from the immune system and have an immunomodulatory effect. In the presence of dysbiosis, the concentration of lipopolysaccharides (LPS) increases, favoring damage to the intestinal barrier. Furthermore, a pro-inflammatory environment prevails, and a ...