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Fto gene: historic background and its relationship with chronic-degenerative diseasesGene FTO: Aspectos históricos y su relación con enfermedades crónicas no comunicables
(Sociedad Latinoamericana de Hipertención, 2018-07-15)
Alteraciones en el desarrollo de la atención
y la organización conductual pueden
configurar cuadros clínicos como
el trastorno déficit de atención (TDA) que puede estar
acompañado o no de hiperactividad (TDAH), este último
parece tener una relación directa con otros diagnósticos
de tipo endocrino como la obesidad. El objetivo del estudio
es analizar la relación que existe entre el TDAH y la
obesidad. Es por ello que se realiza una revisión sistemática
de estudios científicos revelando relaciones y diferencias
entre ambos trastornos desde ...
Insulin resistance indices and coronary risk in adults from Maracaibo city, Venezuela: A cross sectional study [version 1; referees: 1 approved with reservations]
(is published by F1000 Research Ltd, 2018-03)
Background: Insulin resistance (IR) is a metabolic disorder related to
atherosclerosis. Its measurement is of great importance not only as a marker of
diabetes but also for cardiovascular disease. The aim of this research study
was to evaluate the relationship between various IR indices and coronary risk in
an adult population from Maracaibo city, Venezuela.
Methods: The Maracaibo City Metabolic Syndrome Prevalence Study is a
descriptive, cross-sectional study with random and multi-stage sampling. In this
sub study, 1272 individuals of ...
Pyoderma gangrenosum in a patient with type 2 diabetes: a case report
(Universidad del Zulia, 2020)
We are presenting a case of patient with type 2 diabetes mellitus that was diagnosed with a soft tissue infection in the lower extremity. This was initially treated as cellulitis and antibiotic treatment was initiated. Due to a poor clinical response, the diagnosis of pyoderma gangrenosum was proposed as part of the differential diagnosis. Skin biopsies and pathology confirmed the diagnosis of pyoderma gangrenosum that had a satisfactory response to steroid treatment.
Microbiota and Diabetes Mellitus: Role of Lipid Mediators
(MDPI, 2020)
Diabetes Mellitus (DM) is an inflammatory clinical entity with different mechanisms involved in its physiopathology. Among these, the dysfunction of the gut microbiota stands out. Currently, it is understood that lipid products derived from the gut microbiota are capable of interacting with cells from the immune system and have an immunomodulatory effect. In the presence of dysbiosis, the concentration of lipopolysaccharides (LPS) increases, favoring damage to the intestinal barrier. Furthermore, a pro-inflammatory environment prevails, and a ...
Análisis clínico-epidemiológico de las subfracciones HDL2 y HDL3 en adultos de la ciudad de Maracaibo, Venezuela
(Instituto Nacional de Salud. Lima, Perú, 2020)
Objetivo: Realizar un análisis clínico-epidemiológico de las subfracciones de colesterol unido a lipoproteinas de alta densidad (HDL-C, por sus siglas en inglés) en adultos de la ciudad de Maracaibo, Venezuela. Materiales y métodos: Se realizó un estudio descriptivo y transversal de la base de datos del Estudio de Prevalencia de Síndrome Metabólico de Maracaibo, que incluyó 359 individuos de ambos sexos, mayores de 18 años, a quienes se les determinó la concentración sérica de HDL3 y HDL2, así como el índice HDL2/ HDL3; evaluando sus niveles según ...
Age-specific waist circumference cutoff-points for abdominal obesity diagnosis: a personalized strategy for a large Venezuelan population
(Springer, 2021)
Background
Evidence shows that the ageing process is a determining factor in fat distribution, composition, and functionality. The goal of this research was to determine cut-off points for waist circumference according to age in the adult population from Maracaibo city, Venezuela.
Methodology
The Metabolic Syndrome Prevalence Study is a descriptive, cross-sectional study with multi-stage randomized sampling. In this post-hoc analysis 1902 individuals ≥18 years and from both sexes were evaluated. Waist circumference ROC curves were built for ...