• Advanced Glycation End Products: New Clinical and Molecular Perspectives 

      Salazar, Juan; Navarro, Carla; Ortega, Ángel; Nava, Manuel; Morillo, Daniela; Torres, Wheeler; Hernández, Marlon; Cabrera, Mayela; Angarita, Lissé; Ortiz, Rina; Chacín, Maricarmen; D'Marco, Luis; Bermúdez, Valmore (MDPI, 2021)
      Diabetes mellitus (DM) is considered one of the most massive epidemics of the twenty-first century due to its high mortality rates caused mainly due to its complications; therefore, the early identification of such ...
    • Insulin Withdrawal in Diabetic Kidney Disease: What Are We Waiting for? 

      Morillas, Carlos; D'Marco, Luis; Puchadas, María Jesús; Solá-Izquierdo, Eva; Gorriz-Zambrano, Carmen; Bermúdez, Valmore; Gorriz, José Luis (MDPI, 2021)
      The prevalence of type 2 diabetes mellitus worldwide stands at nearly 9.3% and it is estimated that 20–40% of these patients will develop diabetic kidney disease (DKD). DKD is the leading cause of chronic kidney disease ...
    • Is “Leptin Resistance” Another Key Resistance to Manage Type 2 Diabetes? 

      Salazar, Juan; Chávez-Castillo, Mervin; Rojas, Joselyn; Ortega, Ángel; Nava, Manuel; Pérez, José; Rojas, Milagros; Espinoza, Cristobal; Chacín, Maricarmen; Herazo, Yaneth; Angarita, Lissé; Rojas, Diana Marcela; D'Marco, Luis; Bermúdez, Valmore (Bentham Science Publishers, 2020)
      Although novel pharmacological options for the treatment of type 2 diabetes mellitus (DM2) have been observed to modulate the functionality of several key organs in glucose homeostasis, successful regulation of insulin ...
    • The Role of the α Cell in the Pathogenesis of Diabetes: A World beyond the Mirror 

      Martínez, María Sofía; Manzano, Alexander; Olivar, Luis Carlos; Nava, Manuel; Salazar, Juan; D'Marco, Luis; Ortiz, Rina; Chacín, Maricarmen; Guerrero-Wyss, Marion; Cabrera de Bravo, Mayela; Cano, Clímaco; Bermúdez, Valmore; Angarita, Lisse (MDPI, 2021)
      Type 2 Diabetes Mellitus (T2DM) is one of the most prevalent chronic metabolic disorders, and insulin has been placed at the epicentre of its pathophysiological basis. However, the involvement of impaired alpha (α) cell ...
    • The Sick Adipose Tissue: New Insights Into Defective Signaling and Crosstalk With the Myocardium 

      Bermúdez, Valmore; Durán, Pablo; Rojas, Edward; Díaz, María P.; Rivas, José; Nava, Manuel; Chací, Maricarmen; Cabrera de Bravo, Mayela; Carrasquero, Rubén; Cano Ponce, Clímaco; Górriz, José Luis; D'Marco, Luis (Frontiers Media, 2021)
      Adipose tissue (AT) biology is linked to cardiovascular health since obesity is associated with cardiovascular disease (CVD) and positively correlated with excessive visceral fat accumulation. AT signaling to myocardial ...